Question 1

Which of the following Rh-negative patients may be transfused with Rh-positive units when few O-negative units are available in an emergency?

Accepted Answer

A)  Pregnant woman 
B)  Middle-aged male 
C)  25-year-old female 
D)  Neonate 
A)  Pregnant woman 
B)  Middle-aged male 
C)  25-year-old female 
D)  Neonate

Question 2

Neonatal exchange transfusion is performed using which blood preservative?

Accepted Answer

A)  AS-1 
B)  Citrate-phosphate-dextrose (CP
D)  
C)  Citrate-phosphate-dextrose adenine (CPDA-1) 
D)  Both B and C can be safely used 
A)  AS-1 
B)  Citrate-phosphate-dextrose (CP
D)  
C)  Citrate-phosphate-dextrose adenine (CPDA-1) 
D)  Both B and C can be safely used

Question 3

Antithrombin III concentrates are used in the treatment of:

Accepted Answer

A)  dysfibrinogenemia. 
B)  acquired antithrombin III deficiency caused by DIC. 
C)  hereditary antithrombin III deficiency caused by venous thrombosis. 
D)  All of the above 
A)  dysfibrinogenemia. 
B)  acquired antithrombin III deficiency caused by DIC. 
C)  hereditary antithrombin III deficiency caused by venous thrombosis. 
D)  All of the above

Question 4

Which component(s) provide(s) a concentrated source of fibrinogen?

Accepted Answer

A)  Fresh or frozen RBCs and FFP 
B)  FFP and cryoprecipitate 
C)  Cryoprecipitate 
D)  Random donor platelets and plasma 
A)  Fresh or frozen RBCs and FFP 
B)  FFP and cryoprecipitate 
C)  Cryoprecipitate 
D)  Random donor platelets and plasma

Question 5

How is donor platelet survival determined in the recipient?

Accepted Answer

A)  Platelet count increment (1 hour after transfusion) 
B)  Radiolabeled metals 
C)  Antiplatelet antibody detection 
D)  None of the above 
A)  Platelet count increment (1 hour after transfusion) 
B)  Radiolabeled metals 
C)  Antiplatelet antibody detection 
D)  None of the above

Question 6

Which of the following is not an indication for transfusing platelets?

Accepted Answer

A)  Thrombocytopenia with bleeding or invasive procedure 
B)  Disseminated intravascular coagulation 
C)  Chemotherapy for malignancy 
D)  Massive transfusion, platelet count 250,000/µL 
A)  Thrombocytopenia with bleeding or invasive procedure 
B)  Disseminated intravascular coagulation 
C)  Chemotherapy for malignancy 
D)  Massive transfusion, platelet count 250,000/µL

Question 7

How is a coagulation factor unit defined?

Accepted Answer

A)  Activity in 1 mL of pooled plasma 
B)  100% activity in 1 unit/L 
C)  Activity in 100 units/mL 
D)  All of the above 
A)  Activity in 1 mL of pooled plasma 
B)  100% activity in 1 unit/L 
C)  Activity in 100 units/mL 
D)  All of the above

Question 8

Persons making pre-deposit donations for planned surgery will take iron supplements to replenish iron and stimulate:

Accepted Answer

A)  myelopoiesis. 
B)  erythropoiesis. 
C)  thrombopoiesis. 
D)  lymphopoiesis. 
A)  myelopoiesis. 
B)  erythropoiesis. 
C)  thrombopoiesis. 
D)  lymphopoiesis.

Question 9

Which type of autologous transfusion, successful in liver transplants, involves collecting 1 to 2 units from the patient before surgery, using crystalloid to replace blood volume and reinfusing blood at the end of surgery?

Accepted Answer

A)  Intraoperative hemodilution 
B)  Pre-deposit donation 
C)  Intraoperative salvage 
D)  Postoperative salvage 
A)  Intraoperative hemodilution 
B)  Pre-deposit donation 
C)  Intraoperative salvage 
D)  Postoperative salvage

Question 10

Why is it essential that irradiated blood components be used in bone marrow transplant recipients?

Accepted Answer

A)  Irradiation counteracts the effects of neutrophil toxicity. 
B)  Bone marrow recipients demonstrate hyperimmunity to lymphocytes. 
C)  Bone marrow recipients are on immunosuppressive therapy. 
D)  None of the above 
A)  Irradiation counteracts the effects of neutrophil toxicity. 
B)  Bone marrow recipients demonstrate hyperimmunity to lymphocytes. 
C)  Bone marrow recipients are on immunosuppressive therapy. 
D)  None of the above

Question 11

Which type of filter is used in routine blood administration sets to remove gross clots from all blood products?

Accepted Answer

A)  Leukopoor 
B)  170 µm 
C)  100 µm 
D)  50 µm 
A)  Leukopoor 
B)  170 µm 
C)  100 µm 
D)  50 µm

Question 12

For which of the following transfusion candidates would CMV-negative blood be most likely indicated?

Accepted Answer

A)  Renal dialysis patients 
B)  Pregnant women 
C)  Transplant candidates 
D)  CMV seropositive patients 
A)  Renal dialysis patients 
B)  Pregnant women 
C)  Transplant candidates 
D)  CMV seropositive patients

Question 13

Liquid plasma is not indicated for factor_____  deficiency.

Accepted Answer

A)  XI 
B)  V 
C)  II 
D)  X 
A)  XI 
B)  V 
C)  II 
D)  X

Question 14

Which blood product is used in the treatment of DIC?

Accepted Answer

A)  Plasma 
B)  Platelets 
C)  Cryoprecipitate 
D)  All of the above 
A)  Plasma 
B)  Platelets 
C)  Cryoprecipitate 
D)  All of the above

Question 15

All blood components should be transfused within what time period to avoid bacterial contamination issues?

Accepted Answer

A)  4 hours 
B)  6 hours 
C)  8 hours 
D)  24 hours 
A)  4 hours 
B)  6 hours 
C)  8 hours 
D)  24 hours

Question 16

In addition to nonhemolytic febrile transfusion reactions, what other indication exists for washed red blood cells?

Accepted Answer

A)  IgM-deficient patients with anti-IgM 
B)  IgE-deficient patients with anti-IgE 
C)  IgA-deficient patients with anti-IgA 
D)  IgG-deficient patients with anti-IgG 
A)  IgM-deficient patients with anti-IgM 
B)  IgE-deficient patients with anti-IgE 
C)  IgA-deficient patients with anti-IgA 
D)  IgG-deficient patients with anti-IgG

Question 17

The rejection of platelets in multiply transfused patients is called:

Accepted Answer

A)  platelet satellitism. 
B)  stimulation. 
C)  refractoriness. 
D)  urticaria. 
A)  platelet satellitism. 
B)  stimulation. 
C)  refractoriness. 
D)  urticaria.

Question 18

A blood component should be transfused within:

Accepted Answer

A)  1 hour. 
B)  2 hours. 
C)  3 hours. 
D)  4 hours. 
A)  1 hour. 
B)  2 hours. 
C)  3 hours. 
D)  4 hours.

Question 19

Who is at risk for transfusion-associated graft-versus-host disease (TAGVHD)?

Accepted Answer

A)  Hodgkin's lymphoma patients 
B)  Bone marrow transplant recipients 
C)  Persons receiving nonirradiated directed donations 
D)  All of the above 
A)  Hodgkin's lymphoma patients 
B)  Bone marrow transplant recipients 
C)  Persons receiving nonirradiated directed donations 
D)  All of the above

Question 20

What blood component is responsible for most allergic reactions?

Accepted Answer

A)  Platelets 
B)  Plasma 
C)  Red blood cells 
D)  White blood cells 
A)  Platelets 
B)  Plasma 
C)  Red blood cells 
D)  White blood cells

Exam 15: Transfusion Therapy

Which of the following Rh-negative patients may be transfused with Rh-positive units when few O-negative units are available in an emergency?

Neonatal exchange transfusion is performed using which blood preservative?

Antithrombin III concentrates are used in the treatment of:

Which component(s) provide(s) a concentrated source of fibrinogen?

How is donor platelet survival determined in the recipient?

Which of the following is not an indication for transfusing platelets?

How is a coagulation factor unit defined?

Persons making pre-deposit donations for planned surgery will take iron supplements to replenish iron and stimulate:

Which type of autologous transfusion, successful in liver transplants, involves collecting 1 to 2 units from the patient before surgery, using crystalloid to replace blood volume and reinfusing blood at the end of surgery?

Why is it essential that irradiated blood components be used in bone marrow transplant recipients?

Which type of filter is used in routine blood administration sets to remove gross clots from all blood products?

For which of the following transfusion candidates would CMV-negative blood be most likely indicated?

Liquid plasma is not indicated for factor_____ deficiency.

Which blood product is used in the treatment of DIC?

All blood components should be transfused within what time period to avoid bacterial contamination issues?

In addition to nonhemolytic febrile transfusion reactions, what other indication exists for washed red blood cells?

The rejection of platelets in multiply transfused patients is called:

A blood component should be transfused within:

Who is at risk for transfusion-associated graft-versus-host disease (TAGVHD)?

What blood component is responsible for most allergic reactions?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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