Question 1

What effect does aspirin have on platelets?

Accepted Answer

A)  Prevents release of ATP 
B)  Prevents platelet adhesion 
C)  Prevents platelet aggregation 
D)  Inhibits antigen expression 
A)  Prevents release of ATP 
B)  Prevents platelet adhesion 
C)  Prevents platelet aggregation 
D)  Inhibits antigen expression C

Question 2

Which immunoadsorbent has an affinity for IgG classes 1, 2, and 4 and their immune complexes?

Accepted Answer

A)  Charcoal 
B)  Staphylococcal protein A 
C)  DNA 
D)  A antigen 
A)  Charcoal 
B)  Staphylococcal protein A 
C)  DNA 
D)  A antigen B

Question 3

What other technique is available for neonates with sepsis when apheresis is unavailable?

Accepted Answer

A)  A buffy coat prepared from plasma less than 12 hours old 
B)  A buffy coat prepared from red blood cells less than 12 hours old 
C)  A buffy coat prepared from a whole blood unit less than 12 hours old 
D)  A buffy coat prepared from platelets less than 12 hours old 
A)  A buffy coat prepared from plasma less than 12 hours old 
B)  A buffy coat prepared from red blood cells less than 12 hours old 
C)  A buffy coat prepared from a whole blood unit less than 12 hours old 
D)  A buffy coat prepared from platelets less than 12 hours old C

Question 4

A person participating in a serial apheresis program would not:

Accepted Answer

A)  donate more frequently than every 4 weeks. 
B)  lose more than 25 mL of red blood cells per week. 
C)  be monitored for weight loss. 
D)  donate every 72 hours. 
A)  donate more frequently than every 4 weeks. 
B)  lose more than 25 mL of red blood cells per week. 
C)  be monitored for weight loss. 
D)  donate every 72 hours.

Question 5

The specific cell product used for treating sepsis is the:

Accepted Answer

A)  lymphocyte. 
B)  granulocyte. 
C)  monocyte. 
D)  plasmacyte. 
A)  lymphocyte. 
B)  granulocyte. 
C)  monocyte. 
D)  plasmacyte.

Question 6

The hematopoietic progenitor cells that eventually repopulate the bone marrow and also circulate in the blood are called:

Accepted Answer

A)  peripheral blood stem cells (PBS
C) . 
B)  hematopoietic stem cells (HS
C) . 
C)  myeloid stem cells (MS
C) . 
D)  lymphoid stem cells. 
A)  peripheral blood stem cells (PBS
C) . 
B)  hematopoietic stem cells (HS
C) . 
C)  myeloid stem cells (MS
C) . 
D)  lymphoid stem cells.

Question 7

Plasma exchange is most effective when_____  is considered the pathological substance.

Accepted Answer

A)  IgG 
B)  IgM 
C)  IgA 
D)  IgE 
A)  IgG 
B)  IgM 
C)  IgA 
D)  IgE

Question 8

What is the primary anticoagulant used in pheresis procedures?

Accepted Answer

A)  CPDA-1 
B)  Heparin 
C)  Citrate 
D)  EDTA 
A)  CPDA-1 
B)  Heparin 
C)  Citrate 
D)  EDTA

Question 9

Erythrocytapheresis is successful in which of the following conditions?

Accepted Answer

A)  Leukemia 
B)  Colon/rectal cancer 
C)  Malaria 
D)  Waldenstrom's macroglobulinemia 
A)  Leukemia 
B)  Colon/rectal cancer 
C)  Malaria 
D)  Waldenstrom's macroglobulinemia

Question 10

The removal of red blood cells in a hemapheresis procedure is called:

Accepted Answer

A)  thrombocytapheresis. 
B)  plasmapheresis. 
C)  erythrocytapheresis. 
D)  leukapheresis. 
A)  thrombocytapheresis. 
B)  plasmapheresis. 
C)  erythrocytapheresis. 
D)  leukapheresis.

Question 11

Compatibility testing is required for granulocyte concentration if the red blood cell contamination is greater than:

Accepted Answer

A)  20 mL. 
B)  10 mL. 
C)  5 mL. 
D)  15 mL. 
A)  20 mL. 
B)  10 mL. 
C)  5 mL. 
D)  15 mL.

Question 12

Plasmapheresis is synonymous with what term?

Accepted Answer

A)  Plasma exchange 
B)  Antibody exchange 
C)  Plasma dilution 
D)  Antibody dilution 
A)  Plasma exchange 
B)  Antibody exchange 
C)  Plasma dilution 
D)  Antibody dilution

Question 13

In plateletpheresis, which blood component is returned to the donor?

Accepted Answer

A)  Red blood cells 
B)  Platelets 
C)  White blood cells 
D)  Options A and C 
A)  Red blood cells 
B)  Platelets 
C)  White blood cells 
D)  Options A and C

Question 14

What is the definition of apheresis?

Accepted Answer

A)  The process of freezing RBCs in liquid nitrogen 
B)  Separation or removal of a blood component from whole blood 
C)  The addition of EPO to red blood cells to increase 2,3 DPG levels 
D)  The extraction of plasma from a whole blood unit 
A)  The process of freezing RBCs in liquid nitrogen 
B)  Separation or removal of a blood component from whole blood 
C)  The addition of EPO to red blood cells to increase 2,3 DPG levels 
D)  The extraction of plasma from a whole blood unit

Question 15

What is a disadvantage of choosing fresh frozen plasma for fluid replacement in persons undergoing therapeutic plasmapheresis?

Accepted Answer

A)  Citrate toxicity 
B)  Disease transmission 
C)  ABO incompatibility 
D)  All of the above 
A)  Citrate toxicity 
B)  Disease transmission 
C)  ABO incompatibility 
D)  All of the above

Question 16

What possible risk exists when hydroxyethyl starch (HES) concentration has exceeded the renal threshold and excretion is retarded?

Accepted Answer

A)  Blockage of the reticuloendothelial system 
B)  Blockage of the spleen 
C)  Citrate toxicity 
D)  Infiltration of the liver by activated macrophages 
A)  Blockage of the reticuloendothelial system 
B)  Blockage of the spleen 
C)  Citrate toxicity 
D)  Infiltration of the liver by activated macrophages

Question 17

Which of the following terms is defined as the removal of white blood cells with the return of red blood cells, plasma, and platelets?

Accepted Answer

A)  Leukapheresis 
B)  Erythrocytapheresis 
C)  Plasmapheresis 
D)  Plateletpheresis 
A)  Leukapheresis 
B)  Erythrocytapheresis 
C)  Plasmapheresis 
D)  Plateletpheresis

Question 18

Which of the following incorporates membrane filtration technology with intermittent flow centrifugation (IFC) apheresis?

Accepted Answer

A)  Haemonetics V50 
B)  COBE Spectra 
C)  Fenwal Autopheresis-C 
D)  Haemonetics V30 
A)  Haemonetics V50 
B)  COBE Spectra 
C)  Fenwal Autopheresis-C 
D)  Haemonetics V30

Question 19

Which of the following factors influenced the need for apheresis technology?

Accepted Answer

A)  Marked increase in the number of exchange transfusions 
B)  Amputee patients 
C)  The blood component needs of patients on chemotherapy 
D)  AIDS epidemic 
A)  Marked increase in the number of exchange transfusions 
B)  Amputee patients 
C)  The blood component needs of patients on chemotherapy 
D)  AIDS epidemic

Question 20

Which of the following is not an indication for plasmapheresis?

Accepted Answer

A)  To decrease iron deposition in tissues in chronically transfused patients 
B)  To collect rare red blood cell antibodies 
C)  To increase the inventory of AB plasma 
D)  To manufacture Rh-immune globulin 
A)  To decrease iron deposition in tissues in chronically transfused patients 
B)  To collect rare red blood cell antibodies 
C)  To increase the inventory of AB plasma 
D)  To manufacture Rh-immune globulin

Exam 14: Apheresis

What effect does aspirin have on platelets?

Which immunoadsorbent has an affinity for IgG classes 1, 2, and 4 and their immune complexes?

What other technique is available for neonates with sepsis when apheresis is unavailable?

A person participating in a serial apheresis program would not:

The specific cell product used for treating sepsis is the:

The hematopoietic progenitor cells that eventually repopulate the bone marrow and also circulate in the blood are called:

Plasma exchange is most effective when_____ is considered the pathological substance.

What is the primary anticoagulant used in pheresis procedures?

Erythrocytapheresis is successful in which of the following conditions?

The removal of red blood cells in a hemapheresis procedure is called:

Compatibility testing is required for granulocyte concentration if the red blood cell contamination is greater than:

Plasmapheresis is synonymous with what term?

In plateletpheresis, which blood component is returned to the donor?

What is the definition of apheresis?

What is a disadvantage of choosing fresh frozen plasma for fluid replacement in persons undergoing therapeutic plasmapheresis?

What possible risk exists when hydroxyethyl starch (HES) concentration has exceeded the renal threshold and excretion is retarded?

Which of the following terms is defined as the removal of white blood cells with the return of red blood cells, plasma, and platelets?

Which of the following incorporates membrane filtration technology with intermittent flow centrifugation (IFC) apheresis?

Which of the following factors influenced the need for apheresis technology?

Which of the following is not an indication for plasmapheresis?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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