Question 1

What percentage of the female population is Xg(a+)?

Accepted Answer

A)  50% 
B)  66% 
C)  89% 
D)  40% 
A)  50% 
B)  66% 
C)  89% 
D)  40% C

Question 2

Lutheran antibodies are rarely associated with causing hemolytic disease of the newborn (HDN) for which of the following reasons?

Accepted Answer

A)  Lutheran antigens are poorly developed at birth. 
B)  Maternal Lutheran antibodies are absorbed onto glycoproteins on the placenta, decreasing the likelihood of HDN. 
C)  Lutheran antibodies are generally IgM class and normally do not cross the placenta. 
D)  All of the above 
A)  Lutheran antigens are poorly developed at birth. 
B)  Maternal Lutheran antibodies are absorbed onto glycoproteins on the placenta, decreasing the likelihood of HDN. 
C)  Lutheran antibodies are generally IgM class and normally do not cross the placenta. 
D)  All of the above D

Question 3

Why was U antigen included in the MNSs blood group system?

Accepted Answer

A)  U is enhanced by enzyme treatment. 
B)  All U-negative red blood cells were also S-s-. 
C)  All U-positive red blood cells were also S+s+. 
D)  All U-negative red blood cells were also M-N-. 
A)  U is enhanced by enzyme treatment. 
B)  All U-negative red blood cells were also S-s-. 
C)  All U-positive red blood cells were also S+s+. 
D)  All U-negative red blood cells were also M-N-. B

Question 4

What sequence of antigens coincides with strongest immunogen to weakest immunogen?

Accepted Answer

A)  D, Fya, Fyb, K 
B)  D, K, Fya, Fyb 
C)  Fya, Fyb, D, K 
D)  K, Fya, Fyb, D 
A)  D, Fya, Fyb, K 
B)  D, K, Fya, Fyb 
C)  Fya, Fyb, D, K 
D)  K, Fya, Fyb, D

Question 5

Which of the following distinguishes the recessive LuLu gene from the dominant In(Lu) gene?

Accepted Answer

A)  Normal expression of P1 
B)  Abnormal expression of P1 
C)  Expression of the Lu(a-b-) phenotype 
D)  Expression of trace amounts of i antigen 
A)  Normal expression of P1 
B)  Abnormal expression of P1 
C)  Expression of the Lu(a-b-) phenotype 
D)  Expression of trace amounts of i antigen

Question 6

The Dia and Dib antigens are located on:

Accepted Answer

A)  complement receptor one (CRI). 
B)  erythrocyte acetylcholinesterase. 
C)  the anion exchange molecule (AE-1). 
D)  channel-forming integral protein (CHIP). 
A)  complement receptor one (CRI). 
B)  erythrocyte acetylcholinesterase. 
C)  the anion exchange molecule (AE-1). 
D)  channel-forming integral protein (CHIP).

Question 7

What organism is capable of converting Jk(b-) red blood cells to Jk(b+)?

Accepted Answer

A)  Escherichia coli 
B)  Micrococcus species 
C)  Proteus vulgaris 
D)  Streptococcus pneumoniae 
A)  Escherichia coli 
B)  Micrococcus species 
C)  Proteus vulgaris 
D)  Streptococcus pneumoniae

Question 8

What antibody gives a 1+ reaction in undiluted and diluted samples?

Accepted Answer

A)  High incidence 
B)  Low incidence 
C)  High titer, low avidity 
D)  Low titer, high avidity 
A)  High incidence 
B)  Low incidence 
C)  High titer, low avidity 
D)  Low titer, high avidity

Question 9

Which of the following is true concerning Colton antibodies?

Accepted Answer

A)  Encountered frequently 
B)  Destroyed by enzymes 
C)  React at immediate spin 
D)  Stimulated by red blood cell exposure 
A)  Encountered frequently 
B)  Destroyed by enzymes 
C)  React at immediate spin 
D)  Stimulated by red blood cell exposure

Question 10

A patient was phenotyped for the presence of Lewis antigens (Lea and Leb). A 3+ reaction was observed when patient cells were incubated with anti-Lea. No reaction was observed with anti-Leb. Based on these results, the patient's phenotype is_______________ and the patient is a _______________of ABH substances.

Accepted Answer

A)  Le(a+b-)/secretor 
B)  Le(a-b+)/secretor 
C)  Le(a+b-)/nonsecretor 
D)  Le(a-b+)/nonsecretor 
A)  Le(a+b-)/secretor 
B)  Le(a-b+)/secretor 
C)  Le(a+b-)/nonsecretor 
D)  Le(a-b+)/nonsecretor

Question 11

Where are the Kell blood group antigens found?

Accepted Answer

A)  Red blood cells 
B)  Platelets 
C)  Lymphocytes 
D)  All of the above 
A)  Red blood cells 
B)  Platelets 
C)  Lymphocytes 
D)  All of the above

Question 12

What abnormal blood cell morphology is associated with the McLeod phenotype?

Accepted Answer

A)  Spherocytes 
B)  Ovalocytes 
C)  Sickle cells 
D)  Acanthocytes 
A)  Spherocytes 
B)  Ovalocytes 
C)  Sickle cells 
D)  Acanthocytes

Question 13

All of the following characteristics are consistent with benign anti-I except:

Accepted Answer

A)  it is naturally occurring. 
B)  it is IgM. 
C)  it does not bind complement. 
D)  it is reactive at 4°C. 
A)  it is naturally occurring. 
B)  it is IgM. 
C)  it does not bind complement. 
D)  it is reactive at 4°C.

Question 14

The M and N antigens exhibit dosage. Therefore, if a person inherits the homozygous genotype MM, their red blood cells will react_______________ with anti-M than/as those of a person with a heterozygous genotype of MN.

Accepted Answer

A)  stronger 
B)  weaker 
C)  the same 
D)  none of the above 
A)  stronger 
B)  weaker 
C)  the same 
D)  none of the above

Question 15

At birth, infant cells are rich in _______________, and_______________ is nearly undetectable.

Accepted Answer

A)  I/i 
B)  I/H 
C)  i/I 
D)  H/i 
A)  I/i 
B)  I/H 
C)  i/I 
D)  H/i

Question 16

Which of the following statements about the Lewis system is not true?

Accepted Answer

A)  The Lewis phenotype depends on whether the Se gene is present. 
B)  The system is composed of antigen found in secretions 
C)  Genes of the Lewis system are indicated by LE and le. 
D)  Secretion of Lewis substance is controlled by the Se gene 
A)  The Lewis phenotype depends on whether the Se gene is present. 
B)  The system is composed of antigen found in secretions 
C)  Genes of the Lewis system are indicated by LE and le. 
D)  Secretion of Lewis substance is controlled by the Se gene

Question 17

All of the following are characteristics of Kidd antibodies except:

Accepted Answer

A)  IgG immunoglobulins. 
B)  ability to bind complement. 
C)  naturally occurring. 
D)  exhibit dosage. 
A)  IgG immunoglobulins. 
B)  ability to bind complement. 
C)  naturally occurring. 
D)  exhibit dosage.

Question 18

Pregnant women usually express which phenotype?

Accepted Answer

A)  Le(a+b-) 
B)  Le(a+b+) 
C)  Le(a-b-) 
D)  Le(a-b+) 
A)  Le(a+b-) 
B)  Le(a+b+) 
C)  Le(a-b-) 
D)  Le(a-b+)

Question 19

The high-incidence Gya, Hy, and Joa antigens belong to which blood group system?

Accepted Answer

A)  Wr 
B)  DI 
C)  DO 
D)  Sc 
A)  Wr 
B)  DI 
C)  DO 
D)  Sc

Question 20

Which organ removes cells coated with Jk antibodies from circulation?

Accepted Answer

A)  Spleen 
B)  Liver 
C)  Kidneys 
D)  Bone marrow 
A)  Spleen 
B)  Liver 
C)  Kidneys 
D)  Bone marrow

Exam 8: Blood Group Terminology and the Other Blood Groups

What percentage of the female population is Xg(a+)?

Lutheran antibodies are rarely associated with causing hemolytic disease of the newborn (HDN) for which of the following reasons?

Why was U antigen included in the MNSs blood group system?

What sequence of antigens coincides with strongest immunogen to weakest immunogen?

Which of the following distinguishes the recessive LuLu gene from the dominant In(Lu) gene?

The Dia and Dib antigens are located on:

What organism is capable of converting Jk(b-) red blood cells to Jk(b+)?

What antibody gives a 1+ reaction in undiluted and diluted samples?

Which of the following is true concerning Colton antibodies?

Where are the Kell blood group antigens found?

What abnormal blood cell morphology is associated with the McLeod phenotype?

All of the following characteristics are consistent with benign anti-I except:

The M and N antigens exhibit dosage. Therefore, if a person inherits the homozygous genotype MM, their red blood cells will react_______________ with anti-M than/as those of a person with a heterozygous genotype of MN.

At birth, infant cells are rich in _______________, and_______________ is nearly undetectable.

Which of the following statements about the Lewis system is not true?

All of the following are characteristics of Kidd antibodies except:

Pregnant women usually express which phenotype?

The high-incidence Gya, Hy, and Joa antigens belong to which blood group system?

Which organ removes cells coated with Jk antibodies from circulation?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

Filters

The Di^a and Di^b antigens are located on:

At birth, infant cells are rich in _, and_ is nearly undetectable.

The high-incidence Gy^a, Hy, and Jo^a antigens belong to which blood group system?