Question 1

Which statement is false about giant cell tumors?

Accepted Answer

A)  They are an overexpression of genes including osteoprotegerin ligand (OPGL) 
B)  They are malignant,solitary,irregularly shaped tumors 
C)  They are typically located in the epiphysis in the femur,tibia,radius,and humerus 
D)  They are slow-growing tumors,which extend over the articular cartilage 
A)  They are an overexpression of genes including osteoprotegerin ligand (OPGL) 
B)  They are malignant,solitary,irregularly shaped tumors 
C)  They are typically located in the epiphysis in the femur,tibia,radius,and humerus 
D)  They are slow-growing tumors,which extend over the articular cartilage

Question 2

The calcium crystals that appear in the cartilage,synovial membranes,tendons,and soft tissue of people with chronic gout are called tophi.

Accepted Answer

A) True 
 B)False

Question 3

What do acute alcoholic myopathy,McArdle disease,and disorders of lipid metabolism in muscles have in common?

Accepted Answer

A)  They all are autoimmune diseases. 
B)  They all are deposit immune complexes in muscles. 
C)  They all are a cause in myoglobinuria. 
D)  They all cause progressive muscle weakness. 
A)  They all are autoimmune diseases. 
B)  They all are deposit immune complexes in muscles. 
C)  They all are a cause in myoglobinuria. 
D)  They all cause progressive muscle weakness.

Question 4

What is the most common clinical manifestation of osteoporosis?

Accepted Answer

A)  Bone deformity 
B)  Bone pain 
C)  Pathologic fracture 
D)  Muscle strain 
A)  Bone deformity 
B)  Bone pain 
C)  Pathologic fracture 
D)  Muscle strain

Question 5

MATCHING
Match the phrases with the corresponding characteristics.
-Rhabdomyolysis

Accepted Answer

A) Caused by sedatives and narcotics,particularly street heroin 
B) Caused by viruses,bacteria,and parasites 
C) Exercise intolerance with normal production of lactic acid 
D) Impairs the breakdown of glycogen and production of lactic acid 
E) Autoimmune disease 
A) Caused by sedatives and narcotics,particularly street heroin 
B) Caused by viruses,bacteria,and parasites 
C) Exercise intolerance with normal production of lactic acid 
D) Impairs the breakdown of glycogen and production of lactic acid 
E) Autoimmune disease

Question 6

By the time osteoporosis is visible on x-ray,up to ____% of bone has been lost.

Accepted Answer

A)  30 
B)  40 
C)  50 
D)  60 
A)  30 
B)  40 
C)  50 
D)  60

Question 7

People with gout are at high risk for:

Accepted Answer

A)  renal calculi. 
B)  joint trauma. 
C)  anemia. 
D)  hearing loss. 
A)  renal calculi. 
B)  joint trauma. 
C)  anemia. 
D)  hearing loss.

Question 8

MATCHING
Match the phrases with the corresponding characteristics.
-McArdle disease

Accepted Answer

A) Caused by sedatives and narcotics,particularly street heroin 
B) Caused by viruses,bacteria,and parasites 
C) Exercise intolerance with normal production of lactic acid 
D) Impairs the breakdown of glycogen and production of lactic acid 
E) Autoimmune disease 
A) Caused by sedatives and narcotics,particularly street heroin 
B) Caused by viruses,bacteria,and parasites 
C) Exercise intolerance with normal production of lactic acid 
D) Impairs the breakdown of glycogen and production of lactic acid 
E) Autoimmune disease

Question 9

What characterizes rhabdomyolysis?

Accepted Answer

A)  Paralysis of skeletal muscles resulting from impaired nerve supply 
B)  Smooth muscle degeneration resulting from ischemia 
C)  Lysis of skeletal muscle cells through the initiation of the complement cascade 
D)  Release of myoglobin from damaged striated muscle cells 
A)  Paralysis of skeletal muscles resulting from impaired nerve supply 
B)  Smooth muscle degeneration resulting from ischemia 
C)  Lysis of skeletal muscle cells through the initiation of the complement cascade 
D)  Release of myoglobin from damaged striated muscle cells

Question 10

MATCHING
Match the phrases with the corresponding characteristics.
-Polymyositis

Accepted Answer

A) Caused by sedatives and narcotics,particularly street heroin 
B) Caused by viruses,bacteria,and parasites 
C) Exercise intolerance with normal production of lactic acid 
D) Impairs the breakdown of glycogen and production of lactic acid 
E) Autoimmune disease 
A) Caused by sedatives and narcotics,particularly street heroin 
B) Caused by viruses,bacteria,and parasites 
C) Exercise intolerance with normal production of lactic acid 
D) Impairs the breakdown of glycogen and production of lactic acid 
E) Autoimmune disease

Question 11

What are clinical manifestations of fibromyalgia?

Accepted Answer

A)  Hot,tender,and edematous muscle groups bilaterally 
B)  Fasciculations of the upper and lower extremity muscles 
C)  Exercise intolerance and painful muscle cramps 
D)  Burning or gnawing pain at tender points and profound fatigue 
A)  Hot,tender,and edematous muscle groups bilaterally 
B)  Fasciculations of the upper and lower extremity muscles 
C)  Exercise intolerance and painful muscle cramps 
D)  Burning or gnawing pain at tender points and profound fatigue

Question 12

Which disorder is characterized by the formation of abnormal new bone at an accelerated rate beginning with excessive resorption of spongy bone?

Accepted Answer

A)  Osteomalacia 
B)  Paget disease 
C)  Osteoporosis 
D)  Osteosarcoma 
A)  Osteomalacia 
B)  Paget disease 
C)  Osteoporosis 
D)  Osteosarcoma

Question 13

What type of infectious arthritis is described as having a sudden onset of symptoms of a painful,hot swollen joint with decreased range of motion?

Accepted Answer

A)  Viral arthritis 
B)  Lyme arthritis 
C)  Tuberculosis arthritis 
D)  Spondylarthritis 
A)  Viral arthritis 
B)  Lyme arthritis 
C)  Tuberculosis arthritis 
D)  Spondylarthritis

Question 14

In considering osteomyelitis,what is sequestrum?

Accepted Answer

A)  An area of devascularized and devitalized bone 
B)  An enzyme that phagocytizes necrotic bone 
C)  A subperiosteal abscess 
D)  A layer of new bone surrounding the infected bone 
A)  An area of devascularized and devitalized bone 
B)  An enzyme that phagocytizes necrotic bone 
C)  A subperiosteal abscess 
D)  A layer of new bone surrounding the infected bone

Question 15

Bone is unique among body tissue because after a fracture that destroys bone,a new bone is formed,but there is no scar tissue.

Accepted Answer

A) True 
 B)False

Question 16

Which of the following is a fibrous connective tissue that attaches skeletal muscle to bone?

Accepted Answer

A)  Tendon 
B)  Ligament 
C)  Bursa 
D)  Mesentery 
A)  Tendon 
B)  Ligament 
C)  Bursa 
D)  Mesentery

Question 17

Which joint disease is characterized by joint stiffness on movement that dissipates within 30 minutes and joint pain of weight-bearing joints that usually is relieved by rest?

Accepted Answer

A)  Gouty arthritis 
B)  Rheumatoid arthritis 
C)  Osteoarthritis 
D)  Suppurative arthritis 
A)  Gouty arthritis 
B)  Rheumatoid arthritis 
C)  Osteoarthritis 
D)  Suppurative arthritis

Exam 40: Alterations of Musculoskeletal Function

Which statement is false about giant cell tumors?

The calcium crystals that appear in the cartilage,synovial membranes,tendons,and soft tissue of people with chronic gout are called tophi.

What do acute alcoholic myopathy,McArdle disease,and disorders of lipid metabolism in muscles have in common?

What is the most common clinical manifestation of osteoporosis?

MATCHING Match the phrases with the corresponding characteristics. -Rhabdomyolysis

By the time osteoporosis is visible on x-ray,up to ____% of bone has been lost.

People with gout are at high risk for:

MATCHING Match the phrases with the corresponding characteristics. -McArdle disease

What characterizes rhabdomyolysis?

MATCHING Match the phrases with the corresponding characteristics. -Polymyositis

What are clinical manifestations of fibromyalgia?

Which disorder is characterized by the formation of abnormal new bone at an accelerated rate beginning with excessive resorption of spongy bone?

What type of infectious arthritis is described as having a sudden onset of symptoms of a painful,hot swollen joint with decreased range of motion?

In considering osteomyelitis,what is sequestrum?

Bone is unique among body tissue because after a fracture that destroys bone,a new bone is formed,but there is no scar tissue.

Which of the following is a fibrous connective tissue that attaches skeletal muscle to bone?

Which joint disease is characterized by joint stiffness on movement that dissipates within 30 minutes and joint pain of weight-bearing joints that usually is relieved by rest?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment

Genes and Genetic Diseases

Genes, Environment-Lifestyle, and Common Diseases

Innate Immunity Including Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation Including Hypersensitivies

Infection Including Hivaids

Stress and Disease

Biology of Cancer

Tumor Invasion and Metastasis

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Concepts of Neurologic Dysfunction

Disorders of Neurologic Function

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Reproductive Systems

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations in Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Pulmonary Function in Children

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