Question 1

All living organisms use the same DNA codes to specify proteins.

Accepted Answer

A) True 
 B)False  True

Question 2

What is the most clinically useful technique for prenatal diagnosis of chromosomal abnormalities at 2 months' gestation?

Accepted Answer

A)  Gene mapping 
B)  Linkage analysis 
C)  Amniocentesis 
D)  Chorionic villi biopsy 
A)  Gene mapping 
B)  Linkage analysis 
C)  Amniocentesis 
D)  Chorionic villi biopsy D

Question 3

DNA formation and protein synthesis occur in the cell nucleus.

Accepted Answer

A) True 
 B)False  False

Question 4

MATCHING
Match the genetic terms with the corresponding diseases.(Terms can be used more than once. )
-Huntington disease

Accepted Answer

A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive 
A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive

Question 5

Males are affected more often by X-linked recessive genes than females.

Accepted Answer

A) True 
 B)False

Question 6

Match the disease with its chromosomal abnormality.
-Single X chromosome with no homologous X or Y chromosome

Accepted Answer

A) Down Syndrome 
B) Fragile X syndrome 
C) Klinefelter syndrome 
D) Turner syndrome 
E) Cri du chat 
A) Down Syndrome 
B) Fragile X syndrome 
C) Klinefelter syndrome 
D) Turner syndrome 
E) Cri du chat

Question 7

MATCHING
Match the genetic terms with the corresponding diseases.(Terms can be used more than once. )
-Phenylketonuria (PKU)

Accepted Answer

A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive 
A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive

Question 8

Deoxyribonucleic acid (DNA)directs the synthesis of all of the body's proteins.

Accepted Answer

A) True 
 B)False

Question 9

Frameshift mutation has no impact on amino acid sequence in protein synthesis.

Accepted Answer

A) True 
 B)False

Question 10

RNA polymerase is the most important protein in DNA replication.

Accepted Answer

A) True 
 B)False

Question 11

In most cases of recessive disease,both parents of affected individuals are heterozygous carriers.

Accepted Answer

A) True 
 B)False

Question 12

A couple has two children with a genetic disease.What is the probability that the next child will have the same genetic disease?

Accepted Answer

A)  One sixth 
B)  One fourth 
C)  One third 
D)  One half 
A)  One sixth 
B)  One fourth 
C)  One third 
D)  One half

Question 13

If a boy who has hemophilia A inherited it from his:

Accepted Answer

A)  father. 
B)  mother. 
C)  mother and father. 
A)  father. 
B)  mother. 
C)  mother and father.

Question 14

Which of the following disorders has a mode of inheritance similar to hemophilia A?

Accepted Answer

A)  Cri du chat syndrome 
B)  Duchenne muscular dystrophy (DM
D)  
C)  Polycystic kidney 
D)  Down syndrome 
A)  Cri du chat syndrome 
B)  Duchenne muscular dystrophy (DM
D)  
C)  Polycystic kidney 
D)  Down syndrome

Question 15

Match the disease with its chromosomal abnormality.
-Two X chromosomes and one Y chromosome

Accepted Answer

A) Down Syndrome 
B) Fragile X syndrome 
C) Klinefelter syndrome 
D) Turner syndrome 
E) Cri du chat 
A) Down Syndrome 
B) Fragile X syndrome 
C) Klinefelter syndrome 
D) Turner syndrome 
E) Cri du chat

Question 16

If a boy inherits a disease that is autosomal recessive,he inherited it from his:

Accepted Answer

A)  father. 
B)  mother. 
C)  father and mother. 
A)  father. 
B)  mother. 
C)  father and mother.

Question 17

MATCHING
Match the genetic terms with the corresponding diseases.(Terms can be used more than once. )
-Sickle cell disease

Accepted Answer

A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive 
A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive

Question 18

Inserting bone marrow cells into an individual who produces abnormal erythrocytes is an example of what therapy?

Accepted Answer

A)  Somatic cell therapy 
B)  Germ cell therapy 
C)  Genetic engineering therapy 
D)  Recombinant DNA therapy 
A)  Somatic cell therapy 
B)  Germ cell therapy 
C)  Genetic engineering therapy 
D)  Recombinant DNA therapy

Question 19

MATCHING
Match the genetic terms with the corresponding diseases.(Terms can be used more than once. )
-Achondroplasia

Accepted Answer

A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive 
A) Autosomal dominant 
B) Autosomal recessive 
C) X-linked dominant 
D) X-linked recessive

Question 20

What is the chromosomal variation that causes Klinefelter syndrome?

Accepted Answer

A)  Nondisjunction of the X chromosome in the father 
B)  Translocation of the X chromosome in the mother 
C)  Nondisjunction of X chromosomes in the mother 
D)  Translocation of the Y chromosome in the father 
A)  Nondisjunction of the X chromosome in the father 
B)  Translocation of the X chromosome in the mother 
C)  Nondisjunction of X chromosomes in the mother 
D)  Translocation of the Y chromosome in the father

Exam 4: Genes and Genetic Diseases

All living organisms use the same DNA codes to specify proteins.

What is the most clinically useful technique for prenatal diagnosis of chromosomal abnormalities at 2 months' gestation?

DNA formation and protein synthesis occur in the cell nucleus.

MATCHING Match the genetic terms with the corresponding diseases.(Terms can be used more than once. ) -Huntington disease

Males are affected more often by X-linked recessive genes than females.

Match the disease with its chromosomal abnormality. -Single X chromosome with no homologous X or Y chromosome

MATCHING Match the genetic terms with the corresponding diseases.(Terms can be used more than once. ) -Phenylketonuria (PKU)

Deoxyribonucleic acid (DNA)directs the synthesis of all of the body's proteins.

Frameshift mutation has no impact on amino acid sequence in protein synthesis.

RNA polymerase is the most important protein in DNA replication.

In most cases of recessive disease,both parents of affected individuals are heterozygous carriers.

A couple has two children with a genetic disease.What is the probability that the next child will have the same genetic disease?

If a boy who has hemophilia A inherited it from his:

Which of the following disorders has a mode of inheritance similar to hemophilia A?

Match the disease with its chromosomal abnormality. -Two X chromosomes and one Y chromosome

If a boy inherits a disease that is autosomal recessive,he inherited it from his:

MATCHING Match the genetic terms with the corresponding diseases.(Terms can be used more than once. ) -Sickle cell disease

Inserting bone marrow cells into an individual who produces abnormal erythrocytes is an example of what therapy?

MATCHING Match the genetic terms with the corresponding diseases.(Terms can be used more than once. ) -Achondroplasia

What is the chromosomal variation that causes Klinefelter syndrome?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment

Genes, Environment-Lifestyle, and Common Diseases

Innate Immunity Including Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation Including Hypersensitivies

Infection Including Hivaids

Stress and Disease

Biology of Cancer

Tumor Invasion and Metastasis

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Concepts of Neurologic Dysfunction

Disorders of Neurologic Function

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Reproductive Systems

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations in Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Pulmonary Function in Children

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