Question 1

Match the disease with its chromosomal abnormality.
-An additional chromosome joining the normal homologous pair

Accepted Answer

A) Down Syndrome 
B) Fragile X syndrome 
C) Klinefelter syndrome 
D) Turner syndrome 
E) Cri du chat 
A) Down Syndrome 
B) Fragile X syndrome 
C) Klinefelter syndrome 
D) Turner syndrome 
E) Cri du chat

Question 2

What is transcription?

Accepted Answer

A)  It is the process by which DNA polymerase binds to the promoter site on RNA. 
B)  It is the process by which RNA directs the synthesis of polypeptides for protein synthesis. 
C)  It is the process by which RNA is synthesized from a DNA template. 
D)  It is the process of a mutation of the amino acid sequence by a base pair substitution. 
A)  It is the process by which DNA polymerase binds to the promoter site on RNA. 
B)  It is the process by which RNA directs the synthesis of polypeptides for protein synthesis. 
C)  It is the process by which RNA is synthesized from a DNA template. 
D)  It is the process of a mutation of the amino acid sequence by a base pair substitution.

Question 3

A genetically normal male is always _____ for genes on the X chromosome.

Accepted Answer

A)  homozygous 
B)  heterozygous 
C)  hemizygous 
D)  ambizygous 
A)  homozygous 
B)  heterozygous 
C)  hemizygous 
D)  ambizygous

Question 4

The sequence of bases in DNA is complementary to the bases in the messenger RNA (mRNA)with the exception of:

Accepted Answer

A)  uracil instead of thymine. 
B)  adenine instead of cytosine. 
C)  cytosine instead of guanine. 
D)  guanine instead of uracil. 
A)  uracil instead of thymine. 
B)  adenine instead of cytosine. 
C)  cytosine instead of guanine. 
D)  guanine instead of uracil.

Question 5

What is the genotype for the person who has sickle cell trait?

Accepted Answer

A)  DD 
B)  Dd 
C)  dd 
A)  DD 
B)  Dd 
C)  dd

Question 6

What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent homologous X chromosome with only a single X chromosome present? Her features include a short stature,widely spaced nipples,reduced carrying angle at the elbow and sparse body hair.

Accepted Answer

A)  Down syndrome 
B)  Cri du chat syndrome 
C)  Turner syndrome 
D)  Klinefelter syndrome 
A)  Down syndrome 
B)  Cri du chat syndrome 
C)  Turner syndrome 
D)  Klinefelter syndrome

Question 7

A child born with an autosomal dominant disease was most likely produced by the union of a normal parent with an affected heterozygous parent.

Accepted Answer

A) True 
 B)False

Question 8

For which disease has the chromosomal location NOT been identified?

Accepted Answer

A)  Huntington disease 
B)  Hemophilia A 
C)  Sickle cell disease 
D)  Cystic fibrosis 
A)  Huntington disease 
B)  Hemophilia A 
C)  Sickle cell disease 
D)  Cystic fibrosis

Question 9

What is the role of DNA polymerase in DNA replication?

Accepted Answer

A)  This enzyme travels along the single DNA strand adding the correct nucleotide to the new strand. 
B)  This enzyme travels along the double strand of DNA to unwind the nucleotides of the double helix. 
C)  This enzyme holds the double strand apart while the correct nucleotides are added to the strand. 
D)  This enzyme transports the double strand of DNA from the nucleus to the cytoplasm for protein formation. 
A)  This enzyme travels along the single DNA strand adding the correct nucleotide to the new strand. 
B)  This enzyme travels along the double strand of DNA to unwind the nucleotides of the double helix. 
C)  This enzyme holds the double strand apart while the correct nucleotides are added to the strand. 
D)  This enzyme transports the double strand of DNA from the nucleus to the cytoplasm for protein formation.

Question 10

What is the second most commonly recognized genetic cause of mental retardation?

Accepted Answer

A)  Down syndrome 
B)  Fragile X syndrome 
C)  Klinefelter syndrome 
D)  Turner syndrome 
A)  Down syndrome 
B)  Fragile X syndrome 
C)  Klinefelter syndrome 
D)  Turner syndrome

Exam 4: Genes and Genetic Diseases

Match the disease with its chromosomal abnormality. -An additional chromosome joining the normal homologous pair

What is transcription?

A genetically normal male is always _____ for genes on the X chromosome.

The sequence of bases in DNA is complementary to the bases in the messenger RNA (mRNA)with the exception of:

What is the genotype for the person who has sickle cell trait?

What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent homologous X chromosome with only a single X chromosome present? Her features include a short stature,widely spaced nipples,reduced carrying angle at the elbow and sparse body hair.

A child born with an autosomal dominant disease was most likely produced by the union of a normal parent with an affected heterozygous parent.

For which disease has the chromosomal location NOT been identified?

What is the role of DNA polymerase in DNA replication?

What is the second most commonly recognized genetic cause of mental retardation?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment

Genes, Environment-Lifestyle, and Common Diseases

Innate Immunity Including Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation Including Hypersensitivies

Infection Including Hivaids

Stress and Disease

Biology of Cancer

Tumor Invasion and Metastasis

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Concepts of Neurologic Dysfunction

Disorders of Neurologic Function

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Reproductive Systems

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations in Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Pulmonary Function in Children

Filters