Exam 12: Tumor Invasion and Metastasis

Cells of the gut,hair follicles,and bone marrow are affected by chemotherapy and radiation because they have high rates of cell division.

Interleukin is used as adjuvant therapy for a patient with metastatic renal cell carcinoma.The goal of this type of therapy is to:

Which cytokine is involved in producing cachexia syndrome?

During metastasis,how do cancer cells cause lysis of the basement membrane of the host cell?

Match the mechanisms causing pain from tumor invasion with the organ commonly involved. -Medullary bone

Cells with mutant p53 genes escape apoptosis.

Which biologic therapy produced by B lymphocytes is capable of binding to target cells?

Infection is the most significant cause of complications and death in cancer patients.

Where does seeding of cancer cells occur?

Basal metabolic rates of people with cancer are usually _____ than normal.

All tumor cells that are released into the blood eventually find a compatible tissue to multiply in and create a tumor.

As a tumor increases in size,some cells undergo apoptosis.The only cells to survive and multiply are those with mutations to one copy of the p53 gene.

MATCHING Match the phrases with the corresponding terms. -Chemotherapy

What is the consequence for cells when the functioning p53 gene is lost due to mutation?

Which cells of the immune system provide defense for the host against circulating tumor cells?

Breast cancer cells metastasize to the bone because the chemokines released by the bone attract breast cells to it

Match the mechanisms causing pain from tumor invasion with the organ commonly involved. -Brain

What protects tumor cells within an emboli from the host defenses and facilitates attachment to vascular epithelium?

MATCHING Match the phrases with the corresponding terms. -Biologic response modifiers

All cancers eventually produce pain.