Question 1

Serotonergic neurons in the cat dorsal raphe nucleus stop firing during which behavioral state?

Accepted Answer

A)  REM sleep 
B)  Active waking 
C)  Slow-wave sleep 
D)  Quiet waking 
A)  REM sleep 
B)  Active waking 
C)  Slow-wave sleep 
D)  Quiet waking

Question 2

All serotonin receptors are _______ except for the _______ receptor, which is _______.

Accepted Answer

A)  metabotropic; 5-HT5B; ionotropic 
B)  metabotropic; 5-HT3; ionotropic 
C)  ionotropic; 5-HT2C; metabotropic 
D)  ionotropic; 5-HT1C; metabotropic 
A)  metabotropic; 5-HT5B; ionotropic 
B)  metabotropic; 5-HT3; ionotropic 
C)  ionotropic; 5-HT2C; metabotropic 
D)  ionotropic; 5-HT1C; metabotropic

Question 3

Activation of 5HT1A serotonin receptors can result in all of the following except a(n)

Accepted Answer

A)  increase in Na+ conductance across the cell membrane. 
B)  reduction in cAMP synthesis. 
C)  increase in K+ conductance. 
D)  decrease in firing of the serotonergic neuron. 
A)  increase in Na+ conductance across the cell membrane. 
B)  reduction in cAMP synthesis. 
C)  increase in K+ conductance. 
D)  decrease in firing of the serotonergic neuron.

Question 4

MDMA was originally synthesized by the Merck pharmaceutical company as part of a project to find new substances that would

Accepted Answer

A)  reduce appetite. 
B)  stop bleeding. 
C)  reduce anxiety or nervousness. 
D)  increase energy. 
A)  reduce appetite. 
B)  stop bleeding. 
C)  reduce anxiety or nervousness. 
D)  increase energy.

Question 5

All of the following drugs result in an increase in serotonin levels except

Accepted Answer

A)  DOI. 
B)  MDMA. 
C)  fenfluramine. 
D)  fluoxetine. 
A)  DOI. 
B)  MDMA. 
C)  fenfluramine. 
D)  fluoxetine.

Question 6

Activation of 5HT1A serotonin receptors causes the neuronal membrane to be _______ because _______ channels are opened.

Accepted Answer

A)  hyperpolarized; K+ 
B)  depolarized; K+ 
C)  hyperpolarized; Ca2+ 
D)  depolarized; Na+ 
A)  hyperpolarized; K+ 
B)  depolarized; K+ 
C)  hyperpolarized; Ca2+ 
D)  depolarized; Na+

Question 7

Findings based on ATD and tyrosine hydroxylase inhibitor depletion studies support the theory that the underlying causes of differing symptoms among people with mood or anxiety disorders may be related to abnormalities in

Accepted Answer

A)  signaling among peptide hormones. 
B)  the parasympathetic versus the sympathetic nervous systems. 
C)  the limbic system. 
D)  the serotonergic versus the catecholaminergic systems. 
A)  signaling among peptide hormones. 
B)  the parasympathetic versus the sympathetic nervous systems. 
C)  the limbic system. 
D)  the serotonergic versus the catecholaminergic systems.

Question 8

Where does gut serotonin come from, what triggers its release, and what is its function?

Accepted Answer

The answer of Where does gut serotonin come from, what...

Question 9

Which statement about MDMA is false?

Accepted Answer

A)  It produces an altered state of consciousness. 
B)  It has been proposed as an adjunct to psychotherapy because it can enhance empathy. 
C)  It has definitively been shown to produce degeneration of nerve fibers in all human users. 
D)  It is considered a Schedule I substance according to the DEA. 
A)  It produces an altered state of consciousness. 
B)  It has been proposed as an adjunct to psychotherapy because it can enhance empathy. 
C)  It has definitively been shown to produce degeneration of nerve fibers in all human users. 
D)  It is considered a Schedule I substance according to the DEA.

Question 10

Which statement regarding 5-HT3 receptors is false?

Accepted Answer

A)  Some of them are located on peripheral terminals of the vagus nerve. 
B)  Activation of these receptors inhibits the vomiting center in the brainstem. 
C)  Drugs that block this receptor subtype are used to treat nausea in cancer chemotherapy patients. 
D)  Ondansetron, granisetron, and palonosetron are all 5-HT3 receptor antagonists. 
A)  Some of them are located on peripheral terminals of the vagus nerve. 
B)  Activation of these receptors inhibits the vomiting center in the brainstem. 
C)  Drugs that block this receptor subtype are used to treat nausea in cancer chemotherapy patients. 
D)  Ondansetron, granisetron, and palonosetron are all 5-HT3 receptor antagonists.

Question 11

Which type of aggression has not been observed in animals?

Accepted Answer

A)  Premeditated aggression 
B)  Predatory aggression 
C)  Maternal aggression 
D)  Irritable aggression 
A)  Premeditated aggression 
B)  Predatory aggression 
C)  Maternal aggression 
D)  Irritable aggression

Question 12

What type of meal is most likely to increase brain levels of tryptophan in animals?

Accepted Answer

A)  High carbohydrate, high protein 
B)  High carbohydrate, low protein 
C)  Low carbohydrate, low protein 
D)  Low carbohydrate, high protein 
A)  High carbohydrate, high protein 
B)  High carbohydrate, low protein 
C)  Low carbohydrate, low protein 
D)  Low carbohydrate, high protein

Question 13

If a researcher was exploring a possible link between the activity of serotonergic neurons and behavioral traits in a group of people with personality disorders, she might measure in _______ in these subjects.

Accepted Answer

A)  levels of 5-HIAA in the CSF 
B)  levels of 5-HIAA in the bloodstream 
C)  levels of 5-HT in the CSF 
D)  activity of SERT 
A)  levels of 5-HIAA in the CSF 
B)  levels of 5-HIAA in the bloodstream 
C)  levels of 5-HT in the CSF 
D)  activity of SERT

Question 14

Describe the synthesis of serotonin and explain why tryptophan levels in the brain increase after consumption of a high-carbohydrate, low-protein meal.

Accepted Answer

The answer of Describe the synthesis of serotonin and explain...

Question 15

Mice genetically engineered to lack central serotonin

Accepted Answer

A)  do not survive to birth. 
B)  demonstrate little to no aggressive behavior. 
C)  have difficulty with thermoregulation. 
D)  breathe at a faster rate than wild-type mice. 
A)  do not survive to birth. 
B)  demonstrate little to no aggressive behavior. 
C)  have difficulty with thermoregulation. 
D)  breathe at a faster rate than wild-type mice.

Question 16

Autoreceptors on serotonin terminals are of the _______ subtype, while somatodendritic autoreceptors are of the _______ subtype.

Accepted Answer

A)  5-HT1A; 5-HT3 
B)  5-HT1A; 5-HT1B or 5-HT1D 
C)  5-HT1B or 5-HT1D; 5-HT1A 
D)  5-HT3; 5-HT1A 
A)  5-HT1A; 5-HT3 
B)  5-HT1A; 5-HT1B or 5-HT1D 
C)  5-HT1B or 5-HT1D; 5-HT1A 
D)  5-HT3; 5-HT1A

Question 17

Researchers study the effects of serotonin depletion in human subjects by inducing _______, which is accomplished by _______.

Accepted Answer

A)  LNAA; using the synthesis-blocking drug PCPA 
B)  ATD; administering a special milkshake that is rich in tryptophan hydroxylase 
C)  LNAA; injecting subjects with insulin to alter the ratio of amino acids in the blood 
D)  ATD; administering a "cocktail" of amino acids that compete with tryptophan for entry into the brain 
A)  LNAA; using the synthesis-blocking drug PCPA 
B)  ATD; administering a special milkshake that is rich in tryptophan hydroxylase 
C)  LNAA; injecting subjects with insulin to alter the ratio of amino acids in the blood 
D)  ATD; administering a "cocktail" of amino acids that compete with tryptophan for entry into the brain

Question 18

Experiments with mice show that slow, tonic firing of DRN neurons promotes _______, while burst firing of these neurons promotes _______.

Accepted Answer

A)  hyperactivity; sedation 
B)  aggression; fear 
C)  sleep; wakefulness 
D)  anorexia; feeding behavior 
A)  hyperactivity; sedation 
B)  aggression; fear 
C)  sleep; wakefulness 
D)  anorexia; feeding behavior

Question 19

Signaling between the gut 5-HT and the brain is supported by several studies, one of which showed that firing rate of vagal afferents from the gut was increased by administration

Accepted Answer

A)  of a catecholamine reuptake inhibitor, but not by an SSRI. 
B)  of an SSRI, but not by a catecholamine reuptake inhibitor. 
C)  of PCPA, but not by a catecholamine reuptake inhibitor. 
D)  of MDMA, but not by a catecholamine reuptake inhibitor. 
A)  of a catecholamine reuptake inhibitor, but not by an SSRI. 
B)  of an SSRI, but not by a catecholamine reuptake inhibitor. 
C)  of PCPA, but not by a catecholamine reuptake inhibitor. 
D)  of MDMA, but not by a catecholamine reuptake inhibitor.

Question 20

Most of the tryptophan obtained through diet is converted to _______, through the actions of _______.

Accepted Answer

A)  glucose; MAO and IDO 
B)  kynurenine; IDO or TDO 
C)  glucose; MAO or COMT 
D)  kynurenine; COMT or TDO 
A)  glucose; MAO and IDO 
B)  kynurenine; IDO or TDO 
C)  glucose; MAO or COMT 
D)  kynurenine; COMT or TDO

Serotonergic neurons in the cat dorsal raphe nucleus stop firing during which behavioral state?

All serotonin receptors are ___ except for the _ receptor, which is _____.

Activation of 5HT_1A serotonin receptors can result in all of the following except a(n)

MDMA was originally synthesized by the Merck pharmaceutical company as part of a project to find new substances that would

All of the following drugs result in an increase in serotonin levels except

Activation of 5HT_1A serotonin receptors causes the neuronal membrane to be _ because _ channels are opened.

Findings based on ATD and tyrosine hydroxylase inhibitor depletion studies support the theory that the underlying causes of differing symptoms among people with mood or anxiety disorders may be related to abnormalities in

Where does gut serotonin come from, what triggers its release, and what is its function?

Which statement about MDMA is false?

Which statement regarding 5-HT₃ receptors is false?

Which type of aggression has not been observed in animals?

What type of meal is most likely to increase brain levels of tryptophan in animals?

If a researcher was exploring a possible link between the activity of serotonergic neurons and behavioral traits in a group of people with personality disorders, she might measure in _______ in these subjects.

Describe the synthesis of serotonin and explain why tryptophan levels in the brain increase after consumption of a high-carbohydrate, low-protein meal.

Mice genetically engineered to lack central serotonin

Autoreceptors on serotonin terminals are of the _ subtype, while somatodendritic autoreceptors are of the _ subtype.

Researchers study the effects of serotonin depletion in human subjects by inducing _, which is accomplished by _.

Experiments with mice show that slow, tonic firing of DRN neurons promotes _, while burst firing of these neurons promotes _.

Signaling between the gut 5-HT and the brain is supported by several studies, one of which showed that firing rate of vagal afferents from the gut was increased by administration

Most of the tryptophan obtained through diet is converted to _, through the actions of _.

Principles of Pharmacology

Structure and Function of the Nervous System

Chemical Signaling by Neurotransmitters and Hormones

Methods of Research in Psychopharmacology

Catecholamines

Acetylcholine

Glutamate and Gaba

Drug Abuse and Addiction

Alcohol

The Opioids

Psychomotor Stimulants: Cocaine, Amphetamine, and Related Drugs

Nicotine and Caffeine

Marijuana and the Cannabinoids

Hallucinogens, Pcp, and Ketamine

Inhalants, Ghb, and Anabolic-Androgenic Steroids

Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These Disorders

Affective Disorders: Antidepressants and Mood Stabilizers

Schizophrenia: Antipsychotic Drugs

Neurodegenerative Diseases, by Jennifer R : Yates, Lander University

Filters

Exam 6: Serotonin

Serotonergic neurons in the cat dorsal raphe nucleus stop firing during which behavioral state?

All serotonin receptors are _______ except for the _______ receptor, which is _______.

Activation of 5HT1A serotonin receptors can result in all of the following except a(n)

MDMA was originally synthesized by the Merck pharmaceutical company as part of a project to find new substances that would

All of the following drugs result in an increase in serotonin levels except

Activation of 5HT1A serotonin receptors causes the neuronal membrane to be _______ because _______ channels are opened.

Findings based on ATD and tyrosine hydroxylase inhibitor depletion studies support the theory that the underlying causes of differing symptoms among people with mood or anxiety disorders may be related to abnormalities in

Where does gut serotonin come from, what triggers its release, and what is its function?

Which statement about MDMA is false?

Which statement regarding 5-HT3 receptors is false?

Which type of aggression has not been observed in animals?

What type of meal is most likely to increase brain levels of tryptophan in animals?

If a researcher was exploring a possible link between the activity of serotonergic neurons and behavioral traits in a group of people with personality disorders, she might measure in _______ in these subjects.

Describe the synthesis of serotonin and explain why tryptophan levels in the brain increase after consumption of a high-carbohydrate, low-protein meal.

Mice genetically engineered to lack central serotonin

Autoreceptors on serotonin terminals are of the _______ subtype, while somatodendritic autoreceptors are of the _______ subtype.

Researchers study the effects of serotonin depletion in human subjects by inducing _______, which is accomplished by _______.

Experiments with mice show that slow, tonic firing of DRN neurons promotes _______, while burst firing of these neurons promotes _______.

Signaling between the gut 5-HT and the brain is supported by several studies, one of which showed that firing rate of vagal afferents from the gut was increased by administration

Most of the tryptophan obtained through diet is converted to _______, through the actions of _______.

Principles of Pharmacology

Structure and Function of the Nervous System

Chemical Signaling by Neurotransmitters and Hormones

Methods of Research in Psychopharmacology

Catecholamines

Acetylcholine

Glutamate and Gaba

Drug Abuse and Addiction

Alcohol

The Opioids

Psychomotor Stimulants: Cocaine, Amphetamine, and Related Drugs

Nicotine and Caffeine

Marijuana and the Cannabinoids

Hallucinogens, Pcp, and Ketamine

Inhalants, Ghb, and Anabolic-Androgenic Steroids

Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These Disorders

Affective Disorders: Antidepressants and Mood Stabilizers

Schizophrenia: Antipsychotic Drugs

Neurodegenerative Diseases, by Jennifer R : Yates, Lander University

Filters

All serotonin receptors are ___ except for the _ receptor, which is _____.

Activation of 5HT_1A serotonin receptors can result in all of the following except a(n)

Activation of 5HT_1A serotonin receptors causes the neuronal membrane to be _ because _ channels are opened.

Which statement regarding 5-HT₃ receptors is false?

Autoreceptors on serotonin terminals are of the _ subtype, while somatodendritic autoreceptors are of the _ subtype.

Researchers study the effects of serotonin depletion in human subjects by inducing _, which is accomplished by _.

Experiments with mice show that slow, tonic firing of DRN neurons promotes _, while burst firing of these neurons promotes _.

Most of the tryptophan obtained through diet is converted to _, through the actions of _.