Question 1

Which of the following is thought to be responsible for tardive dyskinesia in patients taking antipsychotics?

Accepted Answer

A)  Downregulation of D2 receptors 
B)  Upregulation of D2 receptors 
C)  Downregulation of 5-HT2 receptors 
D)  Upregulation of 5-HT2 receptors 
A)  Downregulation of D2 receptors 
B)  Upregulation of D2 receptors 
C)  Downregulation of 5-HT2 receptors 
D)  Upregulation of 5-HT2 receptors

Question 2

Which of the following is not a dopamine pathway affected by antipsychotic medications?

Accepted Answer

A)  Pathway from hypothalamus to pituitary 
B)  Mesocortical pathway 
C)  Pathway from the thalamus to the cortex 
D)  Nigrostriatal pathway 
A)  Pathway from hypothalamus to pituitary 
B)  Mesocortical pathway 
C)  Pathway from the thalamus to the cortex 
D)  Nigrostriatal pathway

Question 3

Describe the research efforts currently underway to address the cognitive symptoms of schizophrenia, including work focused on dopamine, acetylcholine, and glutamate.

Accepted Answer

The answer of Describe the research efforts currently underway to...

Question 4

Which statement about molecular genetic research on schizophrenia is true?

Accepted Answer

A)  It has moved forward on the assumption that schizophrenia involves a single gene. 
B)  It has identified potential "schizophrenia genes" on chromosomes 10 and 14. 
C)  It involves identifying immune disorders in people with schizophrenia. 
D)  At present, 145 loci have been identified as likely sites for genes that increase the risk for developing schizophrenia 
A)  It has moved forward on the assumption that schizophrenia involves a single gene. 
B)  It has identified potential "schizophrenia genes" on chromosomes 10 and 14. 
C)  It involves identifying immune disorders in people with schizophrenia. 
D)  At present, 145 loci have been identified as likely sites for genes that increase the risk for developing schizophrenia

Question 5

Which statement about the effectiveness of the traditional antipsychotic drugs is false?

Accepted Answer

A)  About one-third of patients respond very well to medications and may achieve a relatively normal life. 
B)  Approximately one-third of patients remain hospitalized due to poor response to medication. 
C)  The main therapeutic effect of these medications is to reduce cognitive deficits and emotional responsivity. 
D)  About one-third of patients improve on medications but suffer relapses and need a great deal of support and assistance to deal with daily stresses. 
A)  About one-third of patients respond very well to medications and may achieve a relatively normal life. 
B)  Approximately one-third of patients remain hospitalized due to poor response to medication. 
C)  The main therapeutic effect of these medications is to reduce cognitive deficits and emotional responsivity. 
D)  About one-third of patients improve on medications but suffer relapses and need a great deal of support and assistance to deal with daily stresses.

Question 6

Explain the current thinking on the biopsychosocial etiology of schizophrenia, including the early, latent, and late stages.

Accepted Answer

The answer of Explain the current thinking on the biopsychosocial...

Question 7

The symptoms of schizophrenia that tend to be more difficult to treat are

Accepted Answer

A)  the positive symptoms. 
B)  the positive and the negative symptoms. 
C)  the negative symptoms and the cognitive symptoms. 
D)  the cognitive symptoms and the positive symptoms. 
A)  the positive symptoms. 
B)  the positive and the negative symptoms. 
C)  the negative symptoms and the cognitive symptoms. 
D)  the cognitive symptoms and the positive symptoms.

Question 8

Describe the findings showing that there may be genetic risk factors that make certain people more predisposed to antipsychotic medication side effects.

Accepted Answer

The answer of Describe the findings showing that there may...

Question 9

Describe the evidence linking glutamate abnormalities to schizophrenia, including findings from studies with PCP. What do these findings suggest for treatment possibilities?

Accepted Answer

It has been argued that glutamate hypofu

Question 10

All of the following evidence supports the idea that there is a strong genetic component to schizophrenia except

Accepted Answer

A)  the monozygotic twin concordance rate is 48% but they share 100% of their genes. 
B)  first-degree relatives of schizophrenics are 12 times more likely than the general population to develop schizophrenia at some point in their lifetimes. 
C)  second-degree relatives of schizophrenics are four times more likely than the general population to develop schizophrenia in their lifetimes. 
D)  even when twins are reared apart, the difference in concordance rates is maintained, with the monozygotic rates always higher than the dizygotic rates. 
A)  the monozygotic twin concordance rate is 48% but they share 100% of their genes. 
B)  first-degree relatives of schizophrenics are 12 times more likely than the general population to develop schizophrenia at some point in their lifetimes. 
C)  second-degree relatives of schizophrenics are four times more likely than the general population to develop schizophrenia in their lifetimes. 
D)  even when twins are reared apart, the difference in concordance rates is maintained, with the monozygotic rates always higher than the dizygotic rates.

Question 11

Which model of schizophrenia integrates the neurochemical data with the neuroanatomical findings concerning the disorder?

Accepted Answer

A)  The dopamine hypothesis 
B)  The glutamate-dopamine model 
C)  The DA imbalance hypothesis 
D)  The neurodevelopmental model 
A)  The dopamine hypothesis 
B)  The glutamate-dopamine model 
C)  The DA imbalance hypothesis 
D)  The neurodevelopmental model

Question 12

The time course of effectiveness for antipsychotic medications has been explained by all of the following observations except that

Accepted Answer

A)  dopamine receptor blockade is not directly linked to clinical improvement. 
B)  chronic dopamine autoreceptor blockade may result in receptor supersensitivity, and hence decreased dopamine turnover. 
C)  a depolarization block can occur in response to increased dopamine turnover, which results from the initial antipsychotic drug blockade of receptors. 
D)  over time, antipsychotics decrease their binding to DA receptors and begin to act at other receptor populations. 
A)  dopamine receptor blockade is not directly linked to clinical improvement. 
B)  chronic dopamine autoreceptor blockade may result in receptor supersensitivity, and hence decreased dopamine turnover. 
C)  a depolarization block can occur in response to increased dopamine turnover, which results from the initial antipsychotic drug blockade of receptors. 
D)  over time, antipsychotics decrease their binding to DA receptors and begin to act at other receptor populations.

Question 13

The most all-encompassing perinatal risk factor for schizophrenia appears to be

Accepted Answer

A)  maternal exposure to second-hand smoke. 
B)  maternal and/or fetal inflammatory responses. 
C)  maternal alcohol consumption during pregnancy. 
D)  age of mother during pregnancy. 
A)  maternal exposure to second-hand smoke. 
B)  maternal and/or fetal inflammatory responses. 
C)  maternal alcohol consumption during pregnancy. 
D)  age of mother during pregnancy.

Question 14

Which statement about tardive dyskinesia (TD) is true?

Accepted Answer

A)  It occurs in about 50% to 60% of people treated with neuroleptic medications. 
B)  Its cause is not well understood, but it may be linked to excess dopamine receptors or a D1-D2 receptor imbalance. 
C)  The incidence of TD tends to decrease with increasing age of patients. 
D)  It is a motor side effect of neuroleptics that goes away when drug treatment is stopped. 
A)  It occurs in about 50% to 60% of people treated with neuroleptic medications. 
B)  Its cause is not well understood, but it may be linked to excess dopamine receptors or a D1-D2 receptor imbalance. 
C)  The incidence of TD tends to decrease with increasing age of patients. 
D)  It is a motor side effect of neuroleptics that goes away when drug treatment is stopped.

Which of the following is thought to be responsible for tardive dyskinesia in patients taking antipsychotics?

Which of the following is not a dopamine pathway affected by antipsychotic medications?

Describe the research efforts currently underway to address the cognitive symptoms of schizophrenia, including work focused on dopamine, acetylcholine, and glutamate.

Which statement about molecular genetic research on schizophrenia is true?

Which statement about the effectiveness of the traditional antipsychotic drugs is false?

Explain the current thinking on the biopsychosocial etiology of schizophrenia, including the early, latent, and late stages.

The symptoms of schizophrenia that tend to be more difficult to treat are

Describe the findings showing that there may be genetic risk factors that make certain people more predisposed to antipsychotic medication side effects.

Describe the evidence linking glutamate abnormalities to schizophrenia, including findings from studies with PCP. What do these findings suggest for treatment possibilities?

All of the following evidence supports the idea that there is a strong genetic component to schizophrenia except

Which model of schizophrenia integrates the neurochemical data with the neuroanatomical findings concerning the disorder?

The time course of effectiveness for antipsychotic medications has been explained by all of the following observations except that

The most all-encompassing perinatal risk factor for schizophrenia appears to be

Which statement about tardive dyskinesia (TD) is true?

Principles of Pharmacology

Structure and Function of the Nervous System

Chemical Signaling by Neurotransmitters and Hormones

Methods of Research in Psychopharmacology

Catecholamines

Serotonin

Acetylcholine

Glutamate and Gaba

Drug Abuse and Addiction

Alcohol

The Opioids

Psychomotor Stimulants: Cocaine, Amphetamine, and Related Drugs

Nicotine and Caffeine

Marijuana and the Cannabinoids

Hallucinogens, Pcp, and Ketamine

Inhalants, Ghb, and Anabolic-Androgenic Steroids

Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These Disorders

Affective Disorders: Antidepressants and Mood Stabilizers

Neurodegenerative Diseases, by Jennifer R : Yates, Lander University

Filters

Exam 19: Schizophrenia: Antipsychotic Drugs

Which of the following is thought to be responsible for tardive dyskinesia in patients taking antipsychotics?

Which of the following is not a dopamine pathway affected by antipsychotic medications?

Describe the research efforts currently underway to address the cognitive symptoms of schizophrenia, including work focused on dopamine, acetylcholine, and glutamate.

Which statement about molecular genetic research on schizophrenia is true?

Which statement about the effectiveness of the traditional antipsychotic drugs is false?

Explain the current thinking on the biopsychosocial etiology of schizophrenia, including the early, latent, and late stages.

The symptoms of schizophrenia that tend to be more difficult to treat are

Describe the findings showing that there may be genetic risk factors that make certain people more predisposed to antipsychotic medication side effects.

Describe the evidence linking glutamate abnormalities to schizophrenia, including findings from studies with PCP. What do these findings suggest for treatment possibilities?

All of the following evidence supports the idea that there is a strong genetic component to schizophrenia except

Which model of schizophrenia integrates the neurochemical data with the neuroanatomical findings concerning the disorder?

The time course of effectiveness for antipsychotic medications has been explained by all of the following observations except that

The most all-encompassing perinatal risk factor for schizophrenia appears to be

Which statement about tardive dyskinesia (TD) is true?

Principles of Pharmacology

Structure and Function of the Nervous System

Chemical Signaling by Neurotransmitters and Hormones

Methods of Research in Psychopharmacology

Catecholamines

Serotonin

Acetylcholine

Glutamate and Gaba

Drug Abuse and Addiction

Alcohol

The Opioids

Psychomotor Stimulants: Cocaine, Amphetamine, and Related Drugs

Nicotine and Caffeine

Marijuana and the Cannabinoids

Hallucinogens, Pcp, and Ketamine

Inhalants, Ghb, and Anabolic-Androgenic Steroids

Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These Disorders

Affective Disorders: Antidepressants and Mood Stabilizers

Neurodegenerative Diseases, by Jennifer R : Yates, Lander University

Filters