Question 1

Turner syndrome is an example of a __________ condition.

Accepted Answer

A)  monosomic 
B)  disomic 
C)  trisomic 
D)  polyploid 
E)  fragile site 
A)  monosomic 
B)  disomic 
C)  trisomic 
D)  polyploid 
E)  fragile site

Question 2

MATCHING
Match the genetic disease with the molecular defect
a.Phenylketonuria
d.Tays Sach Disease
b.Sickle cell anemia
e.Hemophilia A
c.Cystic fibrosis
-absence of an enzyme to break down normal membrane lipid

Accepted Answer

The answer of MATCHING
Match the genetic disease with the molecular...

Question 3

Sickle cell anemia and cystic fibrosis are examples of homozygote advantage.
_________________

Accepted Answer

A) True 
 B)False

Question 4

In a chromosomal inversion a segment of a chromosome is:

Accepted Answer

A)  reversed. 
B)  duplicated. 
C)  lost. 
D)  attached to a nonhomologous chromosome. 
E)  deleted 
A)  reversed. 
B)  duplicated. 
C)  lost. 
D)  attached to a nonhomologous chromosome. 
E)  deleted

Question 5

In fragile X syndrome, the fragile X gene contains the nucleotide triplet CGG that repeats 200-1000 times.

Accepted Answer

A) True 
 B)False

Question 6

Hemophilia A is an example of __________ disease and is characterized by a lack of blood-clotting factor __________.

Accepted Answer

A)  an X-linked; VIII 
B)  a sex-linked recessive; V 
C)  an autosomal dominant; VIII 
D)  a sex-linked dominant; V 
E)  an autosomal recessive; VIII 
A)  an X-linked; VIII 
B)  a sex-linked recessive; V 
C)  an autosomal dominant; VIII 
D)  a sex-linked dominant; V 
E)  an autosomal recessive; VIII

Question 7

Maternal PKU can result in serious effects in fetuses.This problem occurs because:

Accepted Answer

A)  the fetus is homozygous for PKU and therefore cannot metabolize phenylalanine. 
B)  the fetus is usually homozygous dominant and therefore has PKU. 
C)  the mother is heterozygous for PKU and therefore cannot metabolize phenylalanine. 
D)  the mother is homozygous dominant for PKU and cannot metabolize phenylalanine. 
E)  the mother is homozygous recessive and cannot metabolize phenylalanine. 
A)  the fetus is homozygous for PKU and therefore cannot metabolize phenylalanine. 
B)  the fetus is usually homozygous dominant and therefore has PKU. 
C)  the mother is heterozygous for PKU and therefore cannot metabolize phenylalanine. 
D)  the mother is homozygous dominant for PKU and cannot metabolize phenylalanine. 
E)  the mother is homozygous recessive and cannot metabolize phenylalanine.

Question 8

Colchicine is a drug that:

Accepted Answer

A)  arrests cells in mitotic telophase. 
B)  stimulates meiosis. 
C)  prevents DNA replication. 
D)  arrests cells in mitotic metaphase. 
E)  prevents cells from entering prophase. 
A)  arrests cells in mitotic telophase. 
B)  stimulates meiosis. 
C)  prevents DNA replication. 
D)  arrests cells in mitotic metaphase. 
E)  prevents cells from entering prophase.

Question 9

Individuals who are __________ for sickle cell hemoglobin tend to be __________ resistant to falciparum malaria, but do not experience the effects of sickled red blood cells.

Accepted Answer

A)  homozygous dominant; more 
B)  homozygous dominant; less 
C)  homozygous recessive; less 
D)  heterozygous; more 
E)  heterozygous; less 
A)  homozygous dominant; more 
B)  homozygous dominant; less 
C)  homozygous recessive; less 
D)  heterozygous; more 
E)  heterozygous; less

Question 10

The normal human karyotype contains __________ chromosomes.

Accepted Answer

A)  22 
B)  23 
C)  44 
D)  46 
E)  54 
A)  22 
B)  23 
C)  44 
D)  46 
E)  54

Question 11

What are the predicted phenotypes of the children from a union of a woman who is heterozygous for hemophilia and a man who is normal? (Use the Punnett square to verify your answer.)

Accepted Answer

A)  100% normal 
B)  75% hemophilia: 25 % normal 
C)  50% hemophilia: 50% normal 
D)  25 % hemophilia: 75% normal 
E)  100% hemophilia 
A)  100% normal 
B)  75% hemophilia: 25 % normal 
C)  50% hemophilia: 50% normal 
D)  25 % hemophilia: 75% normal 
E)  100% hemophilia

Question 12

A genetic counselor would know that the probability of having a child affected with a condition inherited as an autosomal recessive would be:

Accepted Answer

A)  0.5 or 50% if both parents were homozygous normal. 
B)  0.5 or 50% if both parents were heterozygous. 
C)  0.25 or 25% if both parents were homozygous normal. 
D)  0.25 or 25% if both parents were heterozygous. 
E)  0% if both parents were heterozygous. 
A)  0.5 or 50% if both parents were homozygous normal. 
B)  0.5 or 50% if both parents were heterozygous. 
C)  0.25 or 25% if both parents were homozygous normal. 
D)  0.25 or 25% if both parents were heterozygous. 
E)  0% if both parents were heterozygous.

Question 13

A couple in which the woman is homozygous dominant and the man has hemophilia A will produce:

Accepted Answer

A)  carrier daughters and affected sons. 
B)  affected daughters and affected sons. 
C)  carrier daughters and normal sons. 
D)  normal daughters and normal sons. 
E)  offspring of unknown genotype for this gene. 
A)  carrier daughters and affected sons. 
B)  affected daughters and affected sons. 
C)  carrier daughters and normal sons. 
D)  normal daughters and normal sons. 
E)  offspring of unknown genotype for this gene.

Question 14

Human genetics can be effectively studied using:

Accepted Answer

A)  offspring raised under controlled conditions. 
B)  experimental matings between true-breeding strains. 
C)  controlled matings. 
D)  population studies of large extended families. 
E)  population studies of small extended families. 
A)  offspring raised under controlled conditions. 
B)  experimental matings between true-breeding strains. 
C)  controlled matings. 
D)  population studies of large extended families. 
E)  population studies of small extended families.

Question 15

Which statement is true regarding the ethical considerations surrounding human genetics?

Accepted Answer

A)  Genetic discrimination is not a concern in the US with the scant genetic information known now. 
B)  Genetic discrimination is not possible when all the genetic information and its effects are known. 
C)  In the current ethical climate genetic privacy is not a significant concern. 
D)  Consanguineous matings increase the chances of the inheritances of autosomal recessive alleles. 
E)  Insurance companies have no arguments for wanting genetic information on their policy holders. 
A)  Genetic discrimination is not a concern in the US with the scant genetic information known now. 
B)  Genetic discrimination is not possible when all the genetic information and its effects are known. 
C)  In the current ethical climate genetic privacy is not a significant concern. 
D)  Consanguineous matings increase the chances of the inheritances of autosomal recessive alleles. 
E)  Insurance companies have no arguments for wanting genetic information on their policy holders.

Question 16

Cri du chat syndrome arises from:

Accepted Answer

A)  trisomy for chromosome 5. 
B)  deletion of part of chromosome 5. 
C)  a 14/21reciprocal translocation. 
D)  nondisjunction. 
E)  a duplication of part of chromosome 15. 
A)  trisomy for chromosome 5. 
B)  deletion of part of chromosome 5. 
C)  a 14/21reciprocal translocation. 
D)  nondisjunction. 
E)  a duplication of part of chromosome 15.

Question 17

What is the role of heterozygote advantage in maintaining high frequencies of mutant alleles in populations?

Accepted Answer

Concepts to Consider: Heterozygotes for

Question 18

Figure 16-2
Use the figure to answer the corresponding question(s).  
-The inheritance pattern demonstrated by the pedigree in Figure 16-2 is:

Accepted Answer

A)  autosomal recessive. 
B)  autosomal dominant. 
C)  X-linked recessive. 
D)  X-linked dominant. 
E)  unknown from these data. 
A)  autosomal recessive. 
B)  autosomal dominant. 
C)  X-linked recessive. 
D)  X-linked dominant. 
E)  unknown from these data.

Question 19

The Human Genome Project accomplishes all of the following except:

Accepted Answer

A)  sequencing the entire human genome. 
B)  identifying all of the genes in the human genome. 
C)  the foundation for studying gene function in humans. 
D)  basis for studying variations in gene sequences related to illness. 
E)  imprinting a gene with the phenotype of the parent 
A)  sequencing the entire human genome. 
B)  identifying all of the genes in the human genome. 
C)  the foundation for studying gene function in humans. 
D)  basis for studying variations in gene sequences related to illness. 
E)  imprinting a gene with the phenotype of the parent

Question 20

MATCHING
Match the genetic disease with the molecular defect
a.Phenylketonuria
d.Tays Sach Disease
b.Sickle cell anemia
e.Hemophilia A
c.Cystic fibrosis
-Compare and contrast the following three terms: polyploidy, aneuploidy, and nondisjunction.Identify and briefly discuss examples of each of these conditions.

Accepted Answer

Concepts to Consider: Polyploidy is the

Exam 16: Human Genetics and the Human Genome

Turner syndrome is an example of a __________ condition.

MATCHING Match the genetic disease with the molecular defect a.Phenylketonuria d.Tays Sach Disease b.Sickle cell anemia e.Hemophilia A c.Cystic fibrosis -absence of an enzyme to break down normal membrane lipid

Sickle cell anemia and cystic fibrosis are examples of homozygote advantage. _________________

In a chromosomal inversion a segment of a chromosome is:

In fragile X syndrome, the fragile X gene contains the nucleotide triplet CGG that repeats 200-1000 times.

Hemophilia A is an example of __________ disease and is characterized by a lack of blood-clotting factor __________.

Maternal PKU can result in serious effects in fetuses.This problem occurs because:

Colchicine is a drug that:

Individuals who are __________ for sickle cell hemoglobin tend to be __________ resistant to falciparum malaria, but do not experience the effects of sickled red blood cells.

The normal human karyotype contains __________ chromosomes.

What are the predicted phenotypes of the children from a union of a woman who is heterozygous for hemophilia and a man who is normal? (Use the Punnett square to verify your answer.)

A genetic counselor would know that the probability of having a child affected with a condition inherited as an autosomal recessive would be:

A couple in which the woman is homozygous dominant and the man has hemophilia A will produce:

Human genetics can be effectively studied using:

Which statement is true regarding the ethical considerations surrounding human genetics?

Cri du chat syndrome arises from:

What is the role of heterozygote advantage in maintaining high frequencies of mutant alleles in populations?

Figure 16-2 Use the figure to answer the corresponding question(s). -The inheritance pattern demonstrated by the pedigree in Figure 16-2 is:

The Human Genome Project accomplishes all of the following except:

A View of Life

Atoms and Molecules: the Chemical Basis of Life

The Chemistry of Life: Organic Compounds

Organization of the Cell

Biological Membranes

Cell Communication

Energy and Metabolism

How Cells Make Atp: Energy-Releasing Pathways

Photosynthesis: Capturing Light Energy

Chromosomes, Mitosis, and Meiosis

The Basic Principles of Heredity

Dna: the Carrier of Genetic Information

Gene Expression

Gene Regulation

Dna Technology and Genomics

Developmental Genetics

Introduction to Darwinian Evolution

Evolutionary Change in Populations

Speciation and Macroevolution

The Origin and Evolutionary History of Life

The Evolution of Primates

Understanding Diversity: Systematics

Viruses and Subviral Agents

Bacteria and Archaea

Protists

Seedless Plants

Seed Plants

The Fungi

An Introduction to Animal Diversity

Sponges, Cnidarians, Ctenophores, and Protostomes

The Deuterostomes

Plant Structure, Growth, and Development

Leaf Structure and Function

Stem Structure and Transport

Roots and Mineral Nutrition

Reproduction in Flowering Plants

Plant Developmental Responses to External and Internal Signals

Animal Structure and Function: an Introduction

Protection, Support, and Movement

Neural Signaling

Neural Regulation

Sensory Systems

Internal Transport

The Immune System: Internal Defense

Gas Exchange

Processing Food and Nutrition

Osmoregulation and Disposal of Metabolic Wastes

Endocrine Regulation

Reproduction

Animal Development

Animal Behavior

Introduction to Ecology: Population Ecology

Community Ecology

Ecosystems and the Biosphere

Ecology and the Geography of Life

Biological Diversity and Conservation Biology

Filters

Hemophilia A is an example of disease and is characterized by a lack of blood-clotting factor .

Individuals who are for sickle cell hemoglobin tend to be resistant to falciparum malaria, but do not experience the effects of sickled red blood cells.