Question 1

What causes the paresthesia that occurs in vitamin B12 deficiency anemia?

Accepted Answer

A)  Reduction in acetylcholine receptors in the post-synaptic nerves 
B)  Myelin degeneration in the spinal cord 
C)  Destruction of myelin in peripheral nerves 
D)  Altered function of neurons in the parietal lobe 
A)  Reduction in acetylcholine receptors in the post-synaptic nerves 
B)  Myelin degeneration in the spinal cord 
C)  Destruction of myelin in peripheral nerves 
D)  Altered function of neurons in the parietal lobe

Question 2

Symptoms of polycythemia vera are mainly the result of:

Accepted Answer

A)  a decreased erythrocyte count. 
B)  destruction of erythrocytes. 
C)  increased blood viscosity. 
D)  neurologic involvement. 
A)  a decreased erythrocyte count. 
B)  destruction of erythrocytes. 
C)  increased blood viscosity. 
D)  neurologic involvement.

Question 3

Anemia of chronic disease is a mild to moderate anemia associated with chronic infections,chronic noninfectious inflammatory diseases,and malignancies.Chronic diseases commonly associated with this anemia include all of the following except:

Accepted Answer

A)  rheumatoid arthritis. 
B)  acquired immunodeficiency syndrome (AIDS). 
C)  polycythemia vera. 
D)  systemic lupus erythematosus. 
A)  rheumatoid arthritis. 
B)  acquired immunodeficiency syndrome (AIDS). 
C)  polycythemia vera. 
D)  systemic lupus erythematosus.

Question 4

Which anemia produces small,pale erythrocytes?

Accepted Answer

A)  Folic acid 
B)  Hemolytic 
C)  Iron deficiency 
D)  Pernicious 
A)  Folic acid 
B)  Hemolytic 
C)  Iron deficiency 
D)  Pernicious

Question 5

After a patient has a subtotal gastrectomy,what type of anemia would result?

Accepted Answer

A)  Iron deficiency 
B)  Pernicious 
C)  Folic acid 
D)  Vitamin B12 
A)  Iron deficiency 
B)  Pernicious 
C)  Folic acid 
D)  Vitamin B12

Question 6

MATCHING
Match the phrases with the corresponding terms.(Options may be used more than once. )
-Iron deficiency anemia

Accepted Answer

A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia 
A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia

Question 7

If a man has inherited the gene for sideroblastic anemia,he received it from his:

Accepted Answer

A)  mother. 
B)  father. 
C)  mother and father. 
A)  mother. 
B)  father. 
C)  mother and father.

Question 8

Which of the following anemias is classified as a macrocytic-normochromic anemia?

Accepted Answer

A)  Iron deficiency anemia 
B)  Pernicious anemia 
C)  Sideroblastic anemia 
D)  Hemolytic anemia 
A)  Iron deficiency anemia 
B)  Pernicious anemia 
C)  Sideroblastic anemia 
D)  Hemolytic anemia

Question 9

What is the Schilling test?

Accepted Answer

A)  The administration of radioactive cobalamin and the measurement of its excretion in the urine to test for vitamin B12 deficiency 
B)  The measurement of antigen-antibody immune complexes in the blood to test for hemolytic anemia 
C)  The measurement of serum ferritin and total iron-binding capacity in the blood to test for iron deficiency anemia 
D)  The administration of folate and measurement in 2 hours of its level in a blood sample to test for folic acid deficiency anemia 
A)  The administration of radioactive cobalamin and the measurement of its excretion in the urine to test for vitamin B12 deficiency 
B)  The measurement of antigen-antibody immune complexes in the blood to test for hemolytic anemia 
C)  The measurement of serum ferritin and total iron-binding capacity in the blood to test for iron deficiency anemia 
D)  The administration of folate and measurement in 2 hours of its level in a blood sample to test for folic acid deficiency anemia

Question 10

What is the most common cause of iron deficiency anemia?

Accepted Answer

A)  Decreased dietary intake 
B)  Chronic blood loss 
C)  Vitamin deficiency 
D)  Autoimmune disease 
A)  Decreased dietary intake 
B)  Chronic blood loss 
C)  Vitamin deficiency 
D)  Autoimmune disease

Question 11

In hemolytic anemia,when does jaundice occur?

Accepted Answer

A)  Only when erythrocytes are destroyed in the spleen 
B)  Only when heme destruction exceeds the liver's ability to conjugate and excrete bilirubin 
C)  Only when the patient has elevations in aspartate transaminase (AST)and alanine transaminase (ALT) 
D)  Only when the erythrocytes are coated with an immunoglobulin 
A)  Only when erythrocytes are destroyed in the spleen 
B)  Only when heme destruction exceeds the liver's ability to conjugate and excrete bilirubin 
C)  Only when the patient has elevations in aspartate transaminase (AST)and alanine transaminase (ALT) 
D)  Only when the erythrocytes are coated with an immunoglobulin

Question 12

What is the pathophysiologic process of aplastic anemia?

Accepted Answer

A)  Autoimmune disease against hematopoiesis by activated cytotoxic T cells 
B)  Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells 
C)  Autoimmune disease against hematopoiesis by activated immunoglobulins 
D)  Inherited genetic disorder with recessive x-linked transmission 
A)  Autoimmune disease against hematopoiesis by activated cytotoxic T cells 
B)  Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells 
C)  Autoimmune disease against hematopoiesis by activated immunoglobulins 
D)  Inherited genetic disorder with recessive x-linked transmission

Question 13

Treatment for polycythemia vera involves:

Accepted Answer

A)  therapeutic phlebotomy and radioactive phosphorus. 
B)  restoration of blood volume by plasma expanders. 
C)  the administration of cyanocobalamin. 
D)  iron-replacement therapy. 
E)  blood transfusions. 
A)  therapeutic phlebotomy and radioactive phosphorus. 
B)  restoration of blood volume by plasma expanders. 
C)  the administration of cyanocobalamin. 
D)  iron-replacement therapy. 
E)  blood transfusions.

Question 14

How does atrophy of gastric mucosal cells result in pernicious anemia?

Accepted Answer

A)  Because of erythrocyte destruction 
B)  Because of folic acid malabsorption 
C)  Because of vitamin B12 malabsorption 
D)  Because of poor nutritional intake 
A)  Because of erythrocyte destruction 
B)  Because of folic acid malabsorption 
C)  Because of vitamin B12 malabsorption 
D)  Because of poor nutritional intake

Question 15

The underlying disorder of _____ anemia is defective secretion of intrinsic factor,which is essential for the absorption of vitamin B12.

Accepted Answer

A)  microcytic 
B)  pernicious 
C)  hypochromic 
D)  hemolytic 
A)  microcytic 
B)  pernicious 
C)  hypochromic 
D)  hemolytic

Question 16

When a woman has pernicious anemia,how long will she need to continue this therapy?

Accepted Answer

A)  For 6 to 8 weeks 
B)  For 8 to 12 months 
C)  Until her iron level is normal 
D)  For the rest of her life 
A)  For 6 to 8 weeks 
B)  For 8 to 12 months 
C)  Until her iron level is normal 
D)  For the rest of her life

Question 17

A person with sideroblastic anemia would be likely to have _____ plasma levels of iron.

Accepted Answer

A)  high 
B)  low 
C)  normal 
D)  absent 
A)  high 
B)  low 
C)  normal 
D)  absent

Question 18

Considering oral iron therapy,the ferric form is preferred to the ferrous form because ferric is more readily absorbed.

Accepted Answer

A) True 
 B)False

Question 19

MATCHING
Match the phrases with the corresponding terms.(Options may be used more than once. )
-Aplastic anemia

Accepted Answer

A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia 
A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia

Question 20

Untreated pernicious anemia is fatal,usually because of:

Accepted Answer

A)  brain hypoxiA. 
B)  liver hypoxia. 
C)  heart failure. 
D)  renal failure. 
A)  brain hypoxiA. 
B)  liver hypoxia. 
C)  heart failure. 
D)  renal failure.

Exam 26: Alterations of Erythrocyte Function

What causes the paresthesia that occurs in vitamin B12 deficiency anemia?

Symptoms of polycythemia vera are mainly the result of:

Anemia of chronic disease is a mild to moderate anemia associated with chronic infections,chronic noninfectious inflammatory diseases,and malignancies.Chronic diseases commonly associated with this anemia include all of the following except:

Which anemia produces small,pale erythrocytes?

After a patient has a subtotal gastrectomy,what type of anemia would result?

MATCHING Match the phrases with the corresponding terms.(Options may be used more than once. ) -Iron deficiency anemia

If a man has inherited the gene for sideroblastic anemia,he received it from his:

Which of the following anemias is classified as a macrocytic-normochromic anemia?

What is the Schilling test?

What is the most common cause of iron deficiency anemia?

In hemolytic anemia,when does jaundice occur?

What is the pathophysiologic process of aplastic anemia?

Treatment for polycythemia vera involves:

How does atrophy of gastric mucosal cells result in pernicious anemia?

The underlying disorder of _____ anemia is defective secretion of intrinsic factor,which is essential for the absorption of vitamin B12.

When a woman has pernicious anemia,how long will she need to continue this therapy?

A person with sideroblastic anemia would be likely to have _____ plasma levels of iron.

Considering oral iron therapy,the ferric form is preferred to the ferrous form because ferric is more readily absorbed.

MATCHING Match the phrases with the corresponding terms.(Options may be used more than once. ) -Aplastic anemia

Untreated pernicious anemia is fatal,usually because of:

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment

Genes and Genetic Diseases

Genes, Environment-Lifestyle, and Common Diseases

Innate Immunity Including Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation Including Hypersensitivies

Infection Including Hivaids

Stress and Disease

Biology of Cancer

Tumor Invasion and Metastasis

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Concepts of Neurologic Dysfunction

Disorders of Neurologic Function

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Reproductive Systems

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations in Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Pulmonary Function in Children

Filters

What causes the paresthesia that occurs in vitamin B₁₂ deficiency anemia?

The underlying disorder of _____ anemia is defective secretion of intrinsic factor,which is essential for the absorption of vitamin B₁₂.