Exam 24: The Adaptive Immune Response

Myasthenia gravis is an autoimmune neuromuscular disease characterized by weakness of the skeletal muscles due to antiacetylcholine receptor antibodies. Thymectomy is a successful treatment for this condition in some patients because it

List the steps for the classical complement cascade. Discuss two ways this cascade results in microbial destruction.

Severe combined immunodeficiency is most commonly caused by

A typical antibody molecule has ________ antigen-binding sites.

If infections are spread by person-to-person contact, what percentage of the population will be protected against herd immunity if people are not vaccinated?

The chickenpox vaccine is created with an attenuated virus, and the rabies vaccine with an inactivated virus. This means that the chickenpox virus is a ________, and the rabies virus is ________.

In 2004, doctors successfully used gene therapy with a severely defective leukemia virus to insert a cytokine receptor gene needed for T-cell development into the bone marrow of four children with severe combined immunodeficiency (SCID). What is SCID, and how did doing this procedure address the disease?

An example of an antigen that could stimulate naïve B-cell proliferation and differentiation without the help of a T cell would be a(n) ________ molecule from ________.

The cells involved in shutting down immune responses that help prevent autoimmunity are

Innate lymphoid cells in the gut can be stimulated by