Exam 12: Gene Expression

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The Gal4p protein can simultaneously regulate the five genes involved in galactose metabolism in Saccharomyces cerevisiae, despite binding to a specific 17-base pair upstream activator sequence (UAS), because

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In eukaryotic genes

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The transcription of a gene in-vitro is activated by protein A. This activation is repressed when protein B is present which is coded for on a different chromosome. Before protein B is added, protein A can be isolated from the reaction mixture, but when protein B is also present, only a much larger protein is able to be isolated. What is the explanation for this observation?

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In eukaryotes, DNA binding domains specifically interact with which gene control regions?

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RNA interference (RNAi) is a process whereby

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Regulation of gene expression is essential to maintain cellular homeostasis. Control of gene expression may be achieved by

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Which of the following is NOT a control point for gene expression

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Which of the following statements about the function of the Dicer RNA endonuclease complex is INCORRECT?

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In the lac operon of E. coli

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Eukaryotic genes

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A mutation occurs in the operator region of the lac operon of E. coli, and the repressor protein is unable to bind. Which of the following would occur?

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Regulation of galactose-metabolising enzymes is achieved by

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Regulation of the genes responsible for galactose metabolism in Saccharomyces cerevisiae

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A regulatory cascade of gene expression is when

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In the regulation of the lac operon in Escherichia coli, if both glucose and lactose were available energy sources for the cell, you would NOT expect that

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DNA-binding regulatory proteins or transcription factors

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If the operator region of the trp operon in Escherichia coli were moved to a different section of the chromosome, but was otherwise unchanged, the most likely result would be that

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Some genes are expressed at constant levels (constitutive) whereas others are expressed at different levels in response to stimuli (differential). What kind of expression would you expect a gene to have if it were involved in the biosynthesis of actin, a component of the cytoskeleton?

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A zinc finger DNA binding domain is

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Regulation of gene expression

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