Exam 11: Viral Molecular Biology

The figure below shows the structures involved in attachment of HIV to a host cell. The protein gp120 is represented by the number ________; CCR5 is indicated by ________ and CD4 by ________.

Antiviral agents have been synthesized against specific processes of HIV. Which of the following is a mismatched pair?

Control proteins Cro and CII lead to lysis or lysogeny, respectively. What environmental signal in the host contributes to regulate the amount of CII by influencing the activity of the protease HflB?

Retroelements and transposons compose about what percentage of the sequence of the human genome.

What is an oncolytic virus? Give an example.

Integrated retroviral genomes that have accumulated mutations and can no longer generate virions are known as ________ retroviruses.

Which of the following primers for nucleic acid replication is linked to the appropriate virus?

Explain what happens in individuals infected with HIV who are homozygous for functional CCR5, heterozygous for a CCR5 deletion, or homozygous for a CCR5 deletion.

Describe the replication process of the human immunodeficiency virus (HIV).

Sequences of endogenous retroviruses (HERVs) are remnants of retroviral infections. HERVs have accumulated over millions of years and comprise about 8% of the human genome. Briefly describe the evidence for the expression of HERV-K proteins and virus-like particles in the human embryo. What are the implications of HERV-K products interacting with embryonic factors?