Exam 21: The Immune System: Innate and Adaptive Body Defensives

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  Figure 21.2Using Figure 21.2, match the following: -Area seeded by immunocompetent B and T cells. Figure 21.2Using Figure 21.2, match the following: -Area seeded by immunocompetent B and T cells.

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D

  Figure 21.2Using Figure 21.2, match the following: -What are monoclonal antibodies? How are they produced, and what are some of their clinical uses? Figure 21.2Using Figure 21.2, match the following: -What are monoclonal antibodies? How are they produced, and what are some of their clinical uses?

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Monoclonal antibodies are pure antibody preparations that exhibit specificity for a single antigenic determinant. They are produced from the progeny of a single B cell hybridoma "clone," prepared by injecting a specific antigen into a lab animal and then harvesting sensitized B cells from its spleen. The cells are mixed with myeloma cells and incubated, and the resulting hybridoma cells (B cells fused with myeloma cells) produce the monoclonal antibody. They are used for the diagnosis of pregnancy, certain sexually transmitted diseases, hepatitis, rabies, and for other purposes.

  Figure 21.1Using Figure 21.1, match the following: -What are two general mechanisms by which autoimmune diseases could arise? Figure 21.1Using Figure 21.1, match the following: -What are two general mechanisms by which autoimmune diseases could arise?

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1) Appearance of new self- proteins in the circulation that have not previously been exposed to the immune system. 2) An immune response to foreign antigens resembling self- antigens.

Which of the following cells is the most critical cell in immunity?

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After receiving penicillin intravenously, a 32- year- old male patient has an anaphylactic reaction. The nurse understands that therapeutic management includes what critical items?

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  Figure 21.1Using Figure 21.1, match the following: -Tom gets a cut on his hand. After several days he notes swelling, pain, heat, and redness. Upon opening the wound to relieve the pressure, the presence of pus is noted. What has happened to the wound? Figure 21.1Using Figure 21.1, match the following: -Tom gets a cut on his hand. After several days he notes swelling, pain, heat, and redness. Upon opening the wound to relieve the pressure, the presence of pus is noted. What has happened to the wound?

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Which of the following would be classified as a delayed hypersensitivity reaction?

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Delayed hypersensitivities .

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  Figure 21.2Using Figure 21.2, match the following: -Children born without a thymus must be kept in a germ- free environment if they are to survive. Explain why this is necessary. Figure 21.2Using Figure 21.2, match the following: -Children born without a thymus must be kept in a germ- free environment if they are to survive. Explain why this is necessary.

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Cellular ingestion and destruction of particulate matter is called phagocytosis.

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Which of the following is associated with passive immunity?

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Cytotoxic T cells .

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What is the role of interferon in defense against disease?

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  Figure 21.2Using Figure 21.2, match the following: -Area where B cells become immunocompetent. Figure 21.2Using Figure 21.2, match the following: -Area where B cells become immunocompetent.

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  Figure 21.1Using Figure 21.1, match the following: -Harmful or disease- causing microorganisms are called . Figure 21.1Using Figure 21.1, match the following: -Harmful or disease- causing microorganisms are called .

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A given pathogen will provoke either a cell- mediated response or an antibody- mediated response but not both.

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Small molecules that bind with self- proteins to produce antigenic substances are called .

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A young girl requires a liver transplant due to failure of her liver to function. What is required for her to have a good prognosis and why?

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Both T cells and B cells must accomplish double recognition: They must simultaneously recognize self and nonself to be activated.

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Which of the statements below does not describe antigens?

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