Question 1

Which of the following age groups normally has the lowest mean red cell values (red cell count, hemoglobin, hematocrit)?

Accepted Answer

A)  Preterm premature 
B)  Full-term newborn 
C)  Normal 2-year-old child 
D)  Normal 30-year-old woman 
A)  Preterm premature 
B)  Full-term newborn 
C)  Normal 2-year-old child 
D)  Normal 30-year-old woman A

Question 2

Why is the white count in a normal full-term newborn elevated shortly after birth?

Accepted Answer

A)  A relative loss of plasma occurs. 
B)  An absolute increase in neutrophils occurs. 
C)  An absolute increase in lymphocytes occurs. 
D)  An absolute increase in both neutrophils and lymphocytes occurs. 
A)  A relative loss of plasma occurs. 
B)  An absolute increase in neutrophils occurs. 
C)  An absolute increase in lymphocytes occurs. 
D)  An absolute increase in both neutrophils and lymphocytes occurs. B

Question 3

All of the following are normal peripheral blood RBC findings at birth in a full-term infant except:

Accepted Answer

A)  Nucleated RBCs 
B)  Mean cell volume (MCV) less than 90 fL 
C)  Reticulocytosis of 5% 
D)  Hemoglobin of 20.2 g/dL 
A)  Nucleated RBCs 
B)  Mean cell volume (MCV) less than 90 fL 
C)  Reticulocytosis of 5% 
D)  Hemoglobin of 20.2 g/dL B

Question 4

What is the most likely reason that the red blood cell (RBC) count remains elevated in a newborn for the first 2 weeks of life?

Accepted Answer

A)  A relative loss of plasma occurs during the birth process. 
B)  A significantly longer RBC life span increases the number of red cells in circulation. 
C)  Partial anoxia exists in utero, and erythropoietin increases. 
D)  The switch from fetal to adult hemoglobin causes number of red cells to increase. 
A)  A relative loss of plasma occurs during the birth process. 
B)  A significantly longer RBC life span increases the number of red cells in circulation. 
C)  Partial anoxia exists in utero, and erythropoietin increases. 
D)  The switch from fetal to adult hemoglobin causes number of red cells to increase.

Question 5

Iron deficiency anemia in older adults is most often a result of:

Accepted Answer

A)  Poor nutritional intake of iron 
B)  Malabsorption of iron 
C)  Decreased ability to transport iron because of a decrease in transferrin 
D)  Bleeding in the gastrointestinal tract 
A)  Poor nutritional intake of iron 
B)  Malabsorption of iron 
C)  Decreased ability to transport iron because of a decrease in transferrin 
D)  Bleeding in the gastrointestinal tract

Question 6

Why is there a relative lymphocytosis in a 2 year old?

Accepted Answer

A)  An absolute neutropenia occurs. 
B)  The absolute number of lymphocytes is increased as the immune system develops. 
C)  A greater proportion of neutrophils are marginated. 
D)  Fewer lymphocytes are marginated. 
A)  An absolute neutropenia occurs. 
B)  The absolute number of lymphocytes is increased as the immune system develops. 
C)  A greater proportion of neutrophils are marginated. 
D)  Fewer lymphocytes are marginated.

Question 7

Which of the following is most commonly seen in the population older than70 years?

Accepted Answer

A)  Chronic lymphocytic leukemia 
B)  Chronic myelogenous leukemia 
C)  Essential thrombocytosis 
D)  Acute lymphocytic leukemia 
A)  Chronic lymphocytic leukemia 
B)  Chronic myelogenous leukemia 
C)  Essential thrombocytosis 
D)  Acute lymphocytic leukemia

Question 8

Which of the following is true concerning age-related changes of hemostasis in older adults?

Accepted Answer

A)  Decreased factor VIII 
B)  Decreased platelet activity 
C)  Increased fibrinogen 
D)  Increased fibrinolysis 
A)  Decreased factor VIII 
B)  Decreased platelet activity 
C)  Increased fibrinogen 
D)  Increased fibrinolysis

Question 9

A normal 3-month-old boy has a hemoglobin of 11.2 g/dL. Which of the following is true about his hemoglobin? It is:

Accepted Answer

A)  Higher than that of a normal full-term newborn 
B)  Lower than that of an adult of the same age 
C)  Higher than that of a 14 year old of the same sex 
D)  The same as that of an adult of the same sex 
A)  Higher than that of a normal full-term newborn 
B)  Lower than that of an adult of the same age 
C)  Higher than that of a 14 year old of the same sex 
D)  The same as that of an adult of the same sex

Question 10

A Complete blood count (CBC) is requested on a full-term newborn girl, and the following results are obtained: 
 
What conclusion can be made regarding these data for this infant?

Accepted Answer

A)  All results are normal. 
B)  The white count is elevated. 
C)  Hemoglobin, hematocrit, and MCV are all decreased. 
D)  Red cell count, hemoglobin, and hematocrit are all normal, but MCV is decreased. 
A)  All results are normal. 
B)  The white count is elevated. 
C)  Hemoglobin, hematocrit, and MCV are all decreased. 
D)  Red cell count, hemoglobin, and hematocrit are all normal, but MCV is decreased.

Question 11

What is the normal bone marrow cellularity in the population older than 65 years?

Accepted Answer

A)  90% 
B)  70% 
C)  50% 
D)  30% 
A)  90% 
B)  70% 
C)  50% 
D)  30%

Question 12

An 85-year-old woman has a hemoglobin of 10.5 g/dL. This is:

Accepted Answer

A)  High for a woman of this age 
B)  Normal for this age regardless of sex (i.e., for both male and female patients) 
C)  A sign of an underlying disease and requires further evaluation 
D)  Most likely a myelophthisic anemia 
A)  High for a woman of this age 
B)  Normal for this age regardless of sex (i.e., for both male and female patients) 
C)  A sign of an underlying disease and requires further evaluation 
D)  Most likely a myelophthisic anemia

Question 13

At what age is it normal for bone marrow cellularity to be 80% to 90% (i.e., has very little fat)?

Accepted Answer

A)  At birth 
B)  In an 8 year old 
C)  In a 20 to 40 year old 
D)  In those older than 70 years 
A)  At birth 
B)  In an 8 year old 
C)  In a 20 to 40 year old 
D)  In those older than 70 years

Question 14

Which of the following is more likely to result from poor absorption rather than inadequate nutritional intake in older adults?

Accepted Answer

A)  Folic acid deficiency 
B)  Iron deficiency 
C)  Vitamin B12 deficiency 
D)  Lead deficiency 
A)  Folic acid deficiency 
B)  Iron deficiency 
C)  Vitamin B12 deficiency 
D)  Lead deficiency

Exam 38: Pediatric and Geriatric Hematology

Which of the following age groups normally has the lowest mean red cell values (red cell count, hemoglobin, hematocrit)?

Why is the white count in a normal full-term newborn elevated shortly after birth?

All of the following are normal peripheral blood RBC findings at birth in a full-term infant except:

What is the most likely reason that the red blood cell (RBC) count remains elevated in a newborn for the first 2 weeks of life?

Iron deficiency anemia in older adults is most often a result of:

Why is there a relative lymphocytosis in a 2 year old?

Which of the following is most commonly seen in the population older than70 years?

Which of the following is true concerning age-related changes of hemostasis in older adults?

A normal 3-month-old boy has a hemoglobin of 11.2 g/dL. Which of the following is true about his hemoglobin? It is:

A Complete blood count (CBC) is requested on a full-term newborn girl, and the following results are obtained: What conclusion can be made regarding these data for this infant?

What is the normal bone marrow cellularity in the population older than 65 years?

An 85-year-old woman has a hemoglobin of 10.5 g/dL. This is:

At what age is it normal for bone marrow cellularity to be 80% to 90% (i.e., has very little fat)?

Which of the following is more likely to result from poor absorption rather than inadequate nutritional intake in older adults?

An Overview of Clinical Laboratory Hematology

Safety in the Hematology Laboratory

Specimen Collection

Care and Use of the Microscope

Quality Assurance in Hematology and Hemostasis Testing

Cellular Structure and Function

Hematopoiesis

Erythrocyte Production and Destruction

Energy Metabolism and Membrane Physiology of the Erythrocyte

Hemoglobin Metabolism

Iron Metabolism

Leukocyte Development, Kinetics, and Functions

Platelet Production, Structure, and Function

Routine and Point-Of-Care Testing in Hematology: Manual and Semiautomated Methods

Examination of the Peripheral Blood Film and Correlation With the Complete Blood Count

Bone Marrow Examination

Body Fluids in the Hematology Laboratory

Anemias: Red Blood Cell Morphology and Approach to Diagnosis

Disorders of Iron and Heme Metabolism

Anemias Caused by Defects of Dna Metabolism

Bone Marrow Failure

Introduction to Increased Destruction of Erythrocytes

Intrinsic Defects Leading to Increased Erythrocyte Destruction

Extrinsic Defects Leading to Increased Erythrocytedestructionnonimmune Causes

Extrinsic Defects Leading to Increased Erythrocytedestructionimmune Causes

Hemoglobinopathies Structural Defects in Hemoglobin

Thalassemias

Nonmalignant Leukocyte Disorders

Introduction to Leukocyte Neoplasms

Cytochemistry

Cytogenetics

Molecular Diagnostics in the Clinical Laboratory

Flow Cytometric Analysis in Hematologic Disorders

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Leukemias

Mature Lymphoid Neoplasms

Automated Cell-Counting Instrumentation

Normal Hemostasis and Coagulation

Hemorrhagic Coagulation Disorders

Thrombosis Risk Testing

Thrombocytopenia and Thrombocytosis

Qualitative Disorders of Platelets and Vasculature

Laboratory Evaluation of Hemostasis

Monitoring Antithrombotic Therapies

Coagulation Instrumentation

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