Question 1

Which of the following principles measures the actual coagulation protein rather than fibrin formation?

Accepted Answer

A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Immunologic 
A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Immunologic D

Question 2

Which single instrument development has been the most important improvement in coagulation instrumentation?

Accepted Answer

A)  Multiple-sample dilutions 
B)  Improved flagging 
C)  Random access testing 
D)  Graphing of clot formation 
A)  Multiple-sample dilutions 
B)  Improved flagging 
C)  Random access testing 
D)  Graphing of clot formation C

Question 3

All of the following are considered routine coagulation tests that are available in most large and small clinical laboratories except:

Accepted Answer

A)  Prothrombin time (PT) 
B)  Fibrinogen assay 
C)  Partial thromboplastin time (PTT) 
D)  Antithrombin assay 
A)  Prothrombin time (PT) 
B)  Fibrinogen assay 
C)  Partial thromboplastin time (PTT) 
D)  Antithrombin assay D

Question 4

Automatic performance of certain tests based on the results of other tests is called:

Accepted Answer

A)  Reflex testing 
B)  Interpretive liberty 
C)  Programming flexibility 
D)  Random access 
A)  Reflex testing 
B)  Interpretive liberty 
C)  Programming flexibility 
D)  Random access

Question 5

Which of the following is true regarding advances in automated coagulation instrumentation?

Accepted Answer

A)  Less staff training is required to operate and maintain the equipment than earlier semiautomatic instruments. 
B)  Single-sample testing is possible because of increased precision. 
C)  Newer instruments are less expensive. 
D)  Accuracy is so improved that controls do not need to be run. 
A)  Less staff training is required to operate and maintain the equipment than earlier semiautomatic instruments. 
B)  Single-sample testing is possible because of increased precision. 
C)  Newer instruments are less expensive. 
D)  Accuracy is so improved that controls do not need to be run.

Question 6

Diagnostica Stago coagulation instruments are based on what clot detection principle?

Accepted Answer

A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Nephelometric 
A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Nephelometric

Question 7

Examples of instrument malfunction flags include all of the following except:

Accepted Answer

A)  Temperature error 
B)  Probe not aspirating 
C)  No end point detected 
D)  Hemolysis 
A)  Temperature error 
B)  Probe not aspirating 
C)  No end point detected 
D)  Hemolysis

Question 8

Which of the following most improved safety for laboratory scientists?

Accepted Answer

A)  Closed tube sampling 
B)  Random access 
C)  Expanded computer capabilities 
D)  Improved flagging capabilities 
A)  Closed tube sampling 
B)  Random access 
C)  Expanded computer capabilities 
D)  Improved flagging capabilities

Question 9

Using which principle does plasma become more opaque as a clot forms and the amount of light being detected decreases?

Accepted Answer

A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Immunologic 
A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Immunologic

Question 10

Which of the following assays uses indirect measurement using a chromogenic substrate to quantitate heparin?

Accepted Answer

A)  Protein C 
B)  Thrombin time (TT) 
C)  Anti-Xa assay 
D)  Fibrinogen assay 
A)  Protein C 
B)  Thrombin time (TT) 
C)  Anti-Xa assay 
D)  Fibrinogen assay

Question 11

Which of the following is the most common clot detection principle used for coagulation testing?

Accepted Answer

A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Immunologic 
A)  Photo-optical 
B)  Mechanical 
C)  Chromogenic 
D)  Immunologic

Question 12

Aspirin-induced bleeding and Willebrand disease (VWD), type 1, are detected reliably by:

Accepted Answer

A)  Bleeding time 
B)  Point-of-care testing (POCT) 
C)  PFA 100 Platelet Function Analyzer 
D)  Nephelometry 
A)  Bleeding time 
B)  Point-of-care testing (POCT) 
C)  PFA 100 Platelet Function Analyzer 
D)  Nephelometry

Question 13

What is the greatest disadvantage to photo-optical coagulation instruments?

Accepted Answer

A)  High cost 
B)  Complexity of operation 
C)  Availability is limited 
D)  Interference from lipemia, hemolysis, and hyperbilirubinemia 
A)  High cost 
B)  Complexity of operation 
C)  Availability is limited 
D)  Interference from lipemia, hemolysis, and hyperbilirubinemia

Question 14

Who should select the coagulation instruments for a given laboratory?

Accepted Answer

A)  Laboratory director 
B)  Department manager 
C)  Clinical laboratory scientists 
D)  All of the previously listed individuals working together 
A)  Laboratory director 
B)  Department manager 
C)  Clinical laboratory scientists 
D)  All of the previously listed individuals working together

Exam 47: Coagulation Instrumentation

Which of the following principles measures the actual coagulation protein rather than fibrin formation?

Which single instrument development has been the most important improvement in coagulation instrumentation?

All of the following are considered routine coagulation tests that are available in most large and small clinical laboratories except:

Automatic performance of certain tests based on the results of other tests is called:

Which of the following is true regarding advances in automated coagulation instrumentation?

Diagnostica Stago coagulation instruments are based on what clot detection principle?

Examples of instrument malfunction flags include all of the following except:

Which of the following most improved safety for laboratory scientists?

Using which principle does plasma become more opaque as a clot forms and the amount of light being detected decreases?

Which of the following assays uses indirect measurement using a chromogenic substrate to quantitate heparin?

Which of the following is the most common clot detection principle used for coagulation testing?

Aspirin-induced bleeding and Willebrand disease (VWD), type 1, are detected reliably by:

What is the greatest disadvantage to photo-optical coagulation instruments?

Who should select the coagulation instruments for a given laboratory?

An Overview of Clinical Laboratory Hematology

Safety in the Hematology Laboratory

Specimen Collection

Care and Use of the Microscope

Quality Assurance in Hematology and Hemostasis Testing

Cellular Structure and Function

Hematopoiesis

Erythrocyte Production and Destruction

Energy Metabolism and Membrane Physiology of the Erythrocyte

Hemoglobin Metabolism

Iron Metabolism

Leukocyte Development, Kinetics, and Functions

Platelet Production, Structure, and Function

Routine and Point-Of-Care Testing in Hematology: Manual and Semiautomated Methods

Examination of the Peripheral Blood Film and Correlation With the Complete Blood Count

Bone Marrow Examination

Body Fluids in the Hematology Laboratory

Anemias: Red Blood Cell Morphology and Approach to Diagnosis

Disorders of Iron and Heme Metabolism

Anemias Caused by Defects of Dna Metabolism

Bone Marrow Failure

Introduction to Increased Destruction of Erythrocytes

Intrinsic Defects Leading to Increased Erythrocyte Destruction

Extrinsic Defects Leading to Increased Erythrocytedestructionnonimmune Causes

Extrinsic Defects Leading to Increased Erythrocytedestructionimmune Causes

Hemoglobinopathies Structural Defects in Hemoglobin

Thalassemias

Nonmalignant Leukocyte Disorders

Introduction to Leukocyte Neoplasms

Cytochemistry

Cytogenetics

Molecular Diagnostics in the Clinical Laboratory

Flow Cytometric Analysis in Hematologic Disorders

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Leukemias

Mature Lymphoid Neoplasms

Pediatric and Geriatric Hematology

Automated Cell-Counting Instrumentation

Normal Hemostasis and Coagulation

Hemorrhagic Coagulation Disorders

Thrombosis Risk Testing

Thrombocytopenia and Thrombocytosis

Qualitative Disorders of Platelets and Vasculature

Laboratory Evaluation of Hemostasis

Monitoring Antithrombotic Therapies

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