Question 1

Which of the following describes a diploid cell culture that is not a primary culture?

Accepted Answer

A) It is a culture where tissue is removed from an animal, arranged in a monolayer, and very little cell division occurs. 
B) It is a culture that can divide, but passage is limited to 50 generations. 
C) It often has variable numbers of chromosomes and can be subcultured indefinitely. 
D) This describes the only cells the specimen will be plated on. 
A) It is a culture where tissue is removed from an animal, arranged in a monolayer, and very little cell division occurs. 
B) It is a culture that can divide, but passage is limited to 50 generations. 
C) It often has variable numbers of chromosomes and can be subcultured indefinitely. 
D) This describes the only cells the specimen will be plated on.

Question 2

All of the following methods are used as culture techniques to detect viruses except:

Accepted Answer

A) cell culture. 
B) animal inoculation. 
C) embryonated eggs. 
D) media culture. 
A) cell culture. 
B) animal inoculation. 
C) embryonated eggs. 
D) media culture.

Question 3

What disease does the varicella zoster virus (VZV) cause?

Accepted Answer

A) Mumps 
B) Genital warts 
C) Chickenpox 
D) Rubella 
A) Mumps 
B) Genital warts 
C) Chickenpox 
D) Rubella

Question 4

What virus causes acquired immunodeficiency syndrome (AIDS)?

Accepted Answer

A) Hepatitis C virus (HCV) 
B) Hepatitis B virus (HBV) 
C) Respiratory syncytial virus (RSV) 
D) Human immunodeficiency virus (HIV) 
A) Hepatitis C virus (HCV) 
B) Hepatitis B virus (HBV) 
C) Respiratory syncytial virus (RSV) 
D) Human immunodeficiency virus (HIV)

Question 5

What is another name for HHV-4?

Accepted Answer

A) Varicella-zoster 
B) Cytomegalovirus 
C) Herpes simplex 
D) Epstein-Barr 
A) Varicella-zoster 
B) Cytomegalovirus 
C) Herpes simplex 
D) Epstein-Barr

Question 6

What infectious agent causes Creutzfeldt-Jakob disease, Kuru, and "mad cow" disease?

Accepted Answer

A) Prion 
B) Bacteria 
C) Virus 
D) Parasite 
A) Prion 
B) Bacteria 
C) Virus 
D) Parasite

Question 7

What is another name for HHV-3?

Accepted Answer

A) Varicella-zoster 
B) Cytomegalovirus 
C) Herpes simplex 
D) Epstein-Barr 
A) Varicella-zoster 
B) Cytomegalovirus 
C) Herpes simplex 
D) Epstein-Barr

Question 8

All the following are direct methods for diagnosing viral infections except:

Accepted Answer

A) indirect fluorescent antibody (IF
A) . 
B) direct fluorescent antibody (DF
A) . 
C) radioimmunoassay (RI
A) . 
D) enzyme immunoassay (EI
A) . 
A) indirect fluorescent antibody (IF
A) . 
B) direct fluorescent antibody (DF
A) . 
C) radioimmunoassay (RI
A) . 
D) enzyme immunoassay (EI
A) .

Question 9

Which cancer is associated with Epstein-Barr virus (EBV)?

Accepted Answer

A) Hepatocellular carcinoma 
B) Burkitt's lymphoma 
C) Non-Hodgkin's lymphoma 
D) T-cell leukemia 
A) Hepatocellular carcinoma 
B) Burkitt's lymphoma 
C) Non-Hodgkin's lymphoma 
D) T-cell leukemia

Question 10

A symptomatic congenital infection with cytomegalovirus (CMV) includes all the following symptoms except:

Accepted Answer

A) hepatosplenomegaly. 
B) microcephaly. 
C) chorioretinitis. 
D) meningitis. 
A) hepatosplenomegaly. 
B) microcephaly. 
C) chorioretinitis. 
D) meningitis.

Question 11

What are giant multinucleated cells formed from cell fusion as a result of viral infection?

Accepted Answer

A) Giant cells 
B) Macrophages 
C) Glial cells 
D) Syncytia 
A) Giant cells 
B) Macrophages 
C) Glial cells 
D) Syncytia

Question 12

What is a prion?

Accepted Answer

A) A virion 
B) A viroid 
C) A proteinaceous infectious particle 
D) A lipopolysaccharide infectious particle 
A) A virion 
B) A viroid 
C) A proteinaceous infectious particle 
D) A lipopolysaccharide infectious particle

Question 13

What viral genus causes rabies?

Accepted Answer

A) Lyssavirus 
B) Lassa virus 
C) Marburg virus 
D) Calicivirus 
A) Lyssavirus 
B) Lassa virus 
C) Marburg virus 
D) Calicivirus

Question 14

What virus causes genital herpes?

Accepted Answer

A) Human herpesvirus 6 (HHV-6) 
B) Cytomegalovirus (CMV) 
C) Herpes simplex virus type 2 (HSV-2 or HHV-2) 
D) Human herpesvirus (HHV-5) 
A) Human herpesvirus 6 (HHV-6) 
B) Cytomegalovirus (CMV) 
C) Herpes simplex virus type 2 (HSV-2 or HHV-2) 
D) Human herpesvirus (HHV-5)

Question 15

What virus causes the measles?

Accepted Answer

A) Mumps 
B) Respiratory syncytial virus (RSV) 
C) Herpes virus 6 
D) Rubeola virus 
A) Mumps 
B) Respiratory syncytial virus (RSV) 
C) Herpes virus 6 
D) Rubeola virus

Question 16

The genome of a virus is composed of:

Accepted Answer

A) single-stranded DNA. 
B) RNA. 
C) double-stranded DNA. 
D) any of the above. 
A) single-stranded DNA. 
B) RNA. 
C) double-stranded DNA. 
D) any of the above.

Question 17

What is the most common flavivirus infection in the United States?

Accepted Answer

A) West Nile virus 
B) Eastern equine encephalitis virus 
C) St.Louis encephalitis 
D) Rocky Mountain spotted fever 
A) West Nile virus 
B) Eastern equine encephalitis virus 
C) St.Louis encephalitis 
D) Rocky Mountain spotted fever

Question 18

What type of genome do herpesviruses have?

Accepted Answer

A) ssDNA 
B) ssRNA 
C) dsDNA 
D) Both dsDNA and ssRNA 
A) ssDNA 
B) ssRNA 
C) dsDNA 
D) Both dsDNA and ssRNA

Question 19

What is the most common virus isolated from infants with lower respiratory infections and causes croup, bronchitis, bronchiolitis, and interstitial pneumonia?

Accepted Answer

A) Respiratory syncytial virus (RSV) 
B) Lassa 
C) Rotavirus 
D) Norovirus 
A) Respiratory syncytial virus (RSV) 
B) Lassa 
C) Rotavirus 
D) Norovirus

Question 20

Complications of Epstein-Barr virus (EBV) infection include all the following except:

Accepted Answer

A) acute glomerulonephritis. 
B) Reye's syndrome. 
C) thrombocytopenia purpura with hemolytic anemia. 
D) splenic hemorrhage and rupture. 
A) acute glomerulonephritis. 
B) Reye's syndrome. 
C) thrombocytopenia purpura with hemolytic anemia. 
D) splenic hemorrhage and rupture.

Exam 29: Clinical Virology

Which of the following describes a diploid cell culture that is not a primary culture?

All of the following methods are used as culture techniques to detect viruses except:

What disease does the varicella zoster virus (VZV) cause?

What virus causes acquired immunodeficiency syndrome (AIDS)?

What is another name for HHV-4?

What infectious agent causes Creutzfeldt-Jakob disease, Kuru, and "mad cow" disease?

What is another name for HHV-3?

All the following are direct methods for diagnosing viral infections except:

Which cancer is associated with Epstein-Barr virus (EBV)?

A symptomatic congenital infection with cytomegalovirus (CMV) includes all the following symptoms except:

What are giant multinucleated cells formed from cell fusion as a result of viral infection?

What is a prion?

What viral genus causes rabies?

What virus causes genital herpes?

What virus causes the measles?

The genome of a virus is composed of:

What is the most common flavivirus infection in the United States?

What type of genome do herpesviruses have?

What is the most common virus isolated from infants with lower respiratory infections and causes croup, bronchitis, bronchiolitis, and interstitial pneumonia?

Complications of Epstein-Barr virus (EBV) infection include all the following except:

Bacterial Cell Structure, Physiology, Metabolism, and Genetics

Host-Parasite Interaction

The Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Materials From Infected Sites

Use of Colony Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antimicrobial Agent Mechanisms of Action and Resistance

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, Enterococcus, and Other Catalase-Negative, Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio, Aeromonas, Plesiomonas, and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

The Spirochetes

Chlamydia, Rickettsia and Similar Organisms

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Nontuberculous Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Agents of Bioterror and Forensic Microbiology

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Diseases

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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