Question 1

All the following methods are used by the laboratory to diagnose viral infections except:

Accepted Answer

A) chemiluminescence. 
B) direct detection. 
C) culture. 
D) serologic assays. 
A) chemiluminescence. 
B) direct detection. 
C) culture. 
D) serologic assays. A

Question 2

What virus is the most common cause of viral gastroenteritis in infants and children?

Accepted Answer

A) Rotavirus 
B) Influenzae virus 
C) Torovirus 
D) Respiratory syncytial virus (RSV) 
A) Rotavirus 
B) Influenzae virus 
C) Torovirus 
D) Respiratory syncytial virus (RSV) A

Question 3

What is an unsuitable storage temperature for viruses because it allows the development of ice crystals?

Accepted Answer

A) 4° C 
B) -10° C 
C) -20° C 
D) -70° C 
A) 4° C 
B) -10° C 
C) -20° C 
D) -70° C C

Question 4

Adenoviruses produce all the following types of infections except:

Accepted Answer

A) acute hemorrhagic cystitis. 
B) meningitis. 
C) acute respiratory distress. 
D) epidemic keratoconjunctivitis. 
A) acute hemorrhagic cystitis. 
B) meningitis. 
C) acute respiratory distress. 
D) epidemic keratoconjunctivitis.

Question 5

What virus is the major cause of the common cold?

Accepted Answer

A) Rotavirus 
B) Respiratory syncytial virus (RSV) 
C) Rhinovirus 
D) Norovirus 
A) Rotavirus 
B) Respiratory syncytial virus (RSV) 
C) Rhinovirus 
D) Norovirus

Question 6

Which was the first arenavirus found to cause hemorrhagic fever?

Accepted Answer

A) Ebola 
B) Malta 
C) Junin 
D) Marburg 
A) Ebola 
B) Malta 
C) Junin 
D) Marburg

Question 7

What is the composition of viral transport media?

Accepted Answer

A) Amies media with charcoal 
B) Isotonic buffered saline with protein 
C) Cary-Blair 
D) Cooked meat broth 
A) Amies media with charcoal 
B) Isotonic buffered saline with protein 
C) Cary-Blair 
D) Cooked meat broth

Question 8

What is the correct sequence of viral infection, then destruction of a host cell?

Accepted Answer

A) Attachment, penetration, replication, cell lysis 
B) Penetration, attachment, replication, cell lysis 
C) Replication, penetration, attachment, cell lysis 
D) Penetration, replication, attachment, cell lysis 
A) Attachment, penetration, replication, cell lysis 
B) Penetration, attachment, replication, cell lysis 
C) Replication, penetration, attachment, cell lysis 
D) Penetration, replication, attachment, cell lysis

Question 9

What virus is the most common cause of arboviral encephalitis in the world?

Accepted Answer

A) Ebola 
B) Japanese encephalitis virus 
C) Venezuelan equine encephalitis virus 
D) Eastern equine encephalitis virus 
A) Ebola 
B) Japanese encephalitis virus 
C) Venezuelan equine encephalitis virus 
D) Eastern equine encephalitis virus

Question 10

Which of the following is the best description of a primary cell culture?

Accepted Answer

A) It is a culture where tissue is removed from an animal, arranged in a monolayer, and in which very little cell division occurs. 
B) It is a culture that can divide, but passage is limited to 50 generations. 
C) It often has variable numbers of chromosomes and can be subcultured indefinitely. 
D) This describes the only cells the specimen will be plated on. 
A) It is a culture where tissue is removed from an animal, arranged in a monolayer, and in which very little cell division occurs. 
B) It is a culture that can divide, but passage is limited to 50 generations. 
C) It often has variable numbers of chromosomes and can be subcultured indefinitely. 
D) This describes the only cells the specimen will be plated on.

Question 11

What virus causes the Hantavirus pulmonary syndrome?

Accepted Answer

A) Sin Nombre virus 
B) Dobrava virus 
C) Junin 
D) Lassa 
A) Sin Nombre virus 
B) Dobrava virus 
C) Junin 
D) Lassa

Question 12

What requirements do viruses have for replication?

Accepted Answer

A) They must be inside a living cell. 
B) They must be in an environment where all the necessary amino acids are present. 
C) They can use a dead cell to replicate. 
D) They need to be around dead, decaying flesh so that all the amino acids and enzymes are present. 
A) They must be inside a living cell. 
B) They must be in an environment where all the necessary amino acids are present. 
C) They can use a dead cell to replicate. 
D) They need to be around dead, decaying flesh so that all the amino acids and enzymes are present.

Question 13

All of the following are common problems associated with using serologic methods to diagnose viral infections except:

Accepted Answer

A) the host does not produce specific antibodies to viruses. 
B) serologic assays measure host response rather than directly detecting the virus. 
C) the antibody-producing capabilities of human hosts vary widely. 
D) the antibody level does not correlate with the activity level of the infection. 
A) the host does not produce specific antibodies to viruses. 
B) serologic assays measure host response rather than directly detecting the virus. 
C) the antibody-producing capabilities of human hosts vary widely. 
D) the antibody level does not correlate with the activity level of the infection.

Question 14

Which of the following is the description of continuous cell cultures?

Accepted Answer

A) It is a culture where tissue is removed from an animal, arranged in a monolayer, and in which very little cell division occurs. 
B) It is a culture that can divide, but passage is limited to 50 generations. 
C) It often has variable numbers of chromosomes and can be subcultured indefinitely. 
D) This describes the only cells the specimen will be plated on. 
A) It is a culture where tissue is removed from an animal, arranged in a monolayer, and in which very little cell division occurs. 
B) It is a culture that can divide, but passage is limited to 50 generations. 
C) It often has variable numbers of chromosomes and can be subcultured indefinitely. 
D) This describes the only cells the specimen will be plated on.

Question 15

Which of the following is the description of cytopathic effects in viral culture?

Accepted Answer

A) The way viruses kill the infected host cell 
B) The visual changes produced in an infected cell by a virus 
C) The tears that the virus puts in an infected host cell's membrane 
D) The way the virus lyses the infected cell after all the new virus particles are formed and ready to be released. 
A) The way viruses kill the infected host cell 
B) The visual changes produced in an infected cell by a virus 
C) The tears that the virus puts in an infected host cell's membrane 
D) The way the virus lyses the infected cell after all the new virus particles are formed and ready to be released.

Question 16

When is the best time to collect a specimen for culture from a patient suspected of having a viral disease?

Accepted Answer

A) 1 week after onset of symptoms 
B) 5 days after onset of symptoms 
C) Less than 3 days after onset of symptoms 
D) 2 weeks after onset of symptoms 
A) 1 week after onset of symptoms 
B) 5 days after onset of symptoms 
C) Less than 3 days after onset of symptoms 
D) 2 weeks after onset of symptoms

Question 17

Which virus is a bloodborne pathogen?

Accepted Answer

A) Hepatitis A virus (HAV) 
B) Rabies 
C) Hepatitis C virus (HCV) 
D) Norovirus 
A) Hepatitis A virus (HAV) 
B) Rabies 
C) Hepatitis C virus (HCV) 
D) Norovirus

Question 18

What type of cancer is associated with human papilloma virus (HPV)?

Accepted Answer

A) Lung 
B) Ovarian 
C) Skin 
D) Cervical 
A) Lung 
B) Ovarian 
C) Skin 
D) Cervical

Question 19

All the following viruses cause hemorrhagic fever with renal syndrome (HFRS) except:

Accepted Answer

A) Hantaan virus. 
B) Seoul virus. 
C) Dobrava virus. 
D) calicivirus. 
A) Hantaan virus. 
B) Seoul virus. 
C) Dobrava virus. 
D) calicivirus.

Question 20

What is another name for HHV-5?

Accepted Answer

A) Varicella-zoster 
B) Cytomegalovirus 
C) Herpes simplex 
D) Epstein-Barr 
A) Varicella-zoster 
B) Cytomegalovirus 
C) Herpes simplex 
D) Epstein-Barr

Exam 29: Clinical Virology

All the following methods are used by the laboratory to diagnose viral infections except:

What virus is the most common cause of viral gastroenteritis in infants and children?

What is an unsuitable storage temperature for viruses because it allows the development of ice crystals?

Adenoviruses produce all the following types of infections except:

What virus is the major cause of the common cold?

Which was the first arenavirus found to cause hemorrhagic fever?

What is the composition of viral transport media?

What is the correct sequence of viral infection, then destruction of a host cell?

What virus is the most common cause of arboviral encephalitis in the world?

Which of the following is the best description of a primary cell culture?

What virus causes the Hantavirus pulmonary syndrome?

What requirements do viruses have for replication?

All of the following are common problems associated with using serologic methods to diagnose viral infections except:

Which of the following is the description of continuous cell cultures?

Which of the following is the description of cytopathic effects in viral culture?

When is the best time to collect a specimen for culture from a patient suspected of having a viral disease?

Which virus is a bloodborne pathogen?

What type of cancer is associated with human papilloma virus (HPV)?

All the following viruses cause hemorrhagic fever with renal syndrome (HFRS) except:

What is another name for HHV-5?

Bacterial Cell Structure, Physiology, Metabolism, and Genetics

Host-Parasite Interaction

The Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Materials From Infected Sites

Use of Colony Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antimicrobial Agent Mechanisms of Action and Resistance

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, Enterococcus, and Other Catalase-Negative, Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio, Aeromonas, Plesiomonas, and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

The Spirochetes

Chlamydia, Rickettsia and Similar Organisms

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Nontuberculous Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Agents of Bioterror and Forensic Microbiology

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Diseases

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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