Exam 23: Neoplastic Disease

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_______________, or alterations in taste, can have a profound effect on a patient's ability to ingest an adequate amount of nutrition.

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What is the estimated energy requirement for nonambulatory or sedentary cancer patients?

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Pharmacologic doses of which amino acid may benefit patients undergoing hematopoietic cell transplantation?

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What is the primary tumor marker for ovarian cancer that's found in the blood?

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Which growth factor is used to counteract side effects of certain chemotherapy regimens?

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List the tumor imaging techniques available today.

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In the Tumor Node Metastases (TNM) Staging System, what does "N0" mean?

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It is estimated that 60% of patients with head and neck cancers will present with malnutrition at the time of diagnosis.

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A neoplasm is malignant when it grows without tissue invasion.

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_______________ is the complex of DNA and proteins-primarily histones-in the nucleus of a cell.

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A _______________ neoplasm will spread from the primary tissue to other body tissues

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Cancer of the lung and bronchus remains the number one killer in both men and women.

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Because hair follicles also contain rapidly dividing cells, _______________ is also a common side effect of chemotherapy.

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The most common cause of nausea and vomiting in cancer patients is palliative therapy.

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_______________ stimulates red blood cell formation, and IL-11 increases _______________ production.

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Cancers are characterized by unregulated cell growth, tissue invasion, and _______________.

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AS is a 54-year-old business man who has a family history of lung cancer. AS started smoking at 15; years later, he got what he thought was a very bad cold that lasted for a week, started experiencing pain in his tongue, and was given ibuprofen for pain. He then noticed white sores that were getting bigger in his oral cavity near the tongue. He started feeling generally lousy and was unable to eat because of severe pain; he lost 30 lbs in a month. AS went to the clinic, where they did a biopsy that revealed squamous cell cancer of the tongue. AS has undergone radiation therapy (RT) and surgery to remove the cancer and a restorative surgery was scheduled. Because of the RT, AS has developed mucositis and xerostomia in his oral cavity. All his nodes that were sent to the laboratory tested negative for metastasis, and no further RT was needed. The surgeons felt confident that they had removed all the cancer. HT: 5'11" UBW: 165 lbs WT: 135 lbs Meds: Corticosteroids and antineoplastic (dexamethasone) to reduce inflammation, K depletion, Na retention; and morphine for pain. -Approximately how many grams of protein does AS require according to his current body weight?

(Multiple Choice)
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The most _______________ chemotherapeutic agents include cisplatin, methotrexate, doxorubicin, and cyclophosphamide.

(Short Answer)
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AS is a 54-year-old business man who has a family history of lung cancer. AS started smoking at 15; years later, he got what he thought was a very bad cold that lasted for a week, started experiencing pain in his tongue, and was given ibuprofen for pain. He then noticed white sores that were getting bigger in his oral cavity near the tongue. He started feeling generally lousy and was unable to eat because of severe pain; he lost 30 lbs in a month. AS went to the clinic, where they did a biopsy that revealed squamous cell cancer of the tongue. AS has undergone radiation therapy (RT) and surgery to remove the cancer and a restorative surgery was scheduled. Because of the RT, AS has developed mucositis and xerostomia in his oral cavity. All his nodes that were sent to the laboratory tested negative for metastasis, and no further RT was needed. The surgeons felt confident that they had removed all the cancer. HT: 5'11" UBW: 165 lbs WT: 135 lbs Meds: Corticosteroids and antineoplastic (dexamethasone) to reduce inflammation, K depletion, Na retention; and morphine for pain. -Given AS's weight loss, what would his MD likely diagnose him with?

(Multiple Choice)
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Which of the following drugs works by preventing RNA synthesis and interfering with DNA synthesis by binding DNA?

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