Exam 10: Nutritional Genomics

"Junk DNA" appears to play an important role in the:

Cancer can result from genome-wide _______________ due to inappropriate gene activation and chromosomal instability.

In humans, the inheritance of genes for blue eyes is classified as:

A group of gene variants that occur together is called:

What kind of hereditary disease is cystic fibrosis?

How many pairs of chromosomes comprise the human genome?

How many primary components are present in nucleotides?

Give examples of an autosomal recessive trait and an autosomal dominant disorder.

Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family. -Mr) G's genetic profile shows that he has a variation in the APOE gene, which puts him at higher risk for:

What percentage of human DNA is composed of noncoding DNA?

_______________ is a small noncoding RNA molecule involved in the regulation of gene expression.

Which genotype is most likely associated with dietary and other lifestyle interventions in order to minimize CVD risk?

Which chromosome number is linked to various disease states with nutritional implications including several cancers, type 1 diabetes, and Crohn's disease?

Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family. -Which nutrient should the registered dietician suggest Mrs. G to include in her diet via supplements to reduce the risk of cancer?

Several well-defined cancers have a clearly established genetic inheritance based on mutations in a single gene.

Production and degradation of proteins are influenced by environmental factors such as nutrition.

In addition to the genome sequence, the role of _______________, the microbiome, and modulation of gene expression by dietary factors must also be considered in the overall scope of genome-nutrient interactions.

Identify the disease for which human disease gene was mapped with DNA markers for the first time.

Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family. -In addition to advice on specific nutrients and foods, what should the registered dietician advise Mrs. G to avoid or limit in order to lower her risk of this specific polymorphism?

An individual is called homozygous for a gene when the alleles from both parents for that gene differ.