Question 1

Compare the benefits and risks associated with amniocentesis and chorionic villus sampling.

Accepted Answer

Concepts to Consider: Amniocentesis invo

Question 2

Polyploidy is the:

Accepted Answer

A)  presence of more than two of a certain chromosome 
B)  presence of only one of each chromosome 
C)  presence of one extra chromosome 
D)  presence of multiple sets of chromosomes 
E)  general term for conditions such as Down or Turner syndrome 
A)  presence of more than two of a certain chromosome 
B)  presence of only one of each chromosome 
C)  presence of one extra chromosome 
D)  presence of multiple sets of chromosomes 
E)  general term for conditions such as Down or Turner syndrome

Question 3

Briefly illustrate how nondisjunction in meiosis can result in Down syndrome.

Accepted Answer

The sketch should show how a g

Question 4

Hemophilia A is an example of a(n) _____ disease and is characterized by a lack of blood-clotting factor ____.

Accepted Answer

A)  X-linked; VIII 
B)  sex-linked recessive; V 
C)  autosomal dominant; VIII 
D)  sex-linked dominant; V 
E)  autosomal recessive; VIII 
A)  X-linked; VIII 
B)  sex-linked recessive; V 
C)  autosomal dominant; VIII 
D)  sex-linked dominant; V 
E)  autosomal recessive; VIII

Question 5

Discuss the necessity and benefits of the Genetic Information Nondiscrimination Act (GIN
A) of 2008.

Accepted Answer

The GINA is necessary to protect individ

Question 6

What are the predicted phenotypes of the children from a union of a woman who is heterozygous for hemophilia and a man who is normal? (Use the Punnett square to verify your answer.)

Accepted Answer

A)  100% normal 
B)  75% hemophilia: 25 % normal 
C)  50% hemophilia: 50% normal 
D)  25 % hemophilia: 75% normal 
E)  100% hemophilia 
A)  100% normal 
B)  75% hemophilia: 25 % normal 
C)  50% hemophilia: 50% normal 
D)  25 % hemophilia: 75% normal 
E)  100% hemophilia

Question 7

Down syndrome is an example of a ____ condition.

Accepted Answer

A)  monosomic 
B)  disomic 
C)  trisomic 
D)  polyploid 
E)  transgenic 
A)  monosomic 
B)  disomic 
C)  trisomic 
D)  polyploid 
E)  transgenic

Question 8

Match between columns
                        Premises: de la Chapelle syndrome, in which an unequal crossing over event between the X and Y chromosomes during spermatogenesis results in the transfer of part of the Y chromosome to the X chromosome, resulting in an XX male

Accepted Answer

The Answer of translocation and insertion and inversion and fragile is...

Question 9

Figure 16-2
 
The genotypes of the normal females in the second generation in accompanying figure are:

Accepted Answer

A)  homozygous for albinism 
B)  heterozygous for hair color 
C)  heterozygous for albinism 
D)  X-linked 
E)  unknown 
A)  homozygous for albinism 
B)  heterozygous for hair color 
C)  heterozygous for albinism 
D)  X-linked 
E)  unknown

Question 10

The Human Genome Project was completed in 2012 and revealed a genomic map of 38 million SNPs.

Accepted Answer

A) True 
 B)False

Question 11

The position of a specific gene on a chromosome can be determined by:

Accepted Answer

A)  preparing a karyotype 
B)  southern blotting 
C)  genomic hybridization 
D)  chromosome sorting 
E)  fluorescent in situ hybridization 
A)  preparing a karyotype 
B)  southern blotting 
C)  genomic hybridization 
D)  chromosome sorting 
E)  fluorescent in situ hybridization

Question 12

Karyotyping is useful for determining:

Accepted Answer

A)  the number of chromosomes in an individual 
B)  the presence of recessive traits 
C)  whether a specific gene is missing from a chromosome 
D)  whether gene mutations have occurred 
E)  the presence of sickle cell anemia 
A)  the number of chromosomes in an individual 
B)  the presence of recessive traits 
C)  whether a specific gene is missing from a chromosome 
D)  whether gene mutations have occurred 
E)  the presence of sickle cell anemia

Question 13

Match between columns
                        Premises: Philadelphia chromosome, in which parts of chromosomes 9 and 22 switch places; strongly associated with chronic myelogenous leukemia

Accepted Answer

The Answer of inversion and deletion and genomic imprinting and is...

Question 14

FISH distinguishes chromosomes by using more than one fluorescent-tagged RNA strand, which will bind to complementary DNA sequences on a specific chromosome.

Accepted Answer

A) True 
 B)False

Question 15

Sickle cell anemia and cystic fibrosis are examples of a homozygote advantage.

Accepted Answer

A) True 
 B)False

Question 16

What was revealed with the completion of the Human Genome Project?

Accepted Answer

A)  the sequence of the entire human genome 
B)  the functions of all human genes 
C)  the knowledge that all genetic variations lead to genetic disease 
D)  the knowledge that all genetic variations are found outside of protein-coding regions 
E)  the number, but not the locations, of genes in the human genome 
A)  the sequence of the entire human genome 
B)  the functions of all human genes 
C)  the knowledge that all genetic variations lead to genetic disease 
D)  the knowledge that all genetic variations are found outside of protein-coding regions 
E)  the number, but not the locations, of genes in the human genome

Question 17

Nondisjunction of the XY pair during the first meiotic division can produce sperm with 2 X chromosomes and 2 Y chromosomes.

Accepted Answer

A) True 
 B)False

Question 18

Which of the following are inborn errors of metabolism?

Accepted Answer

A)  PKU and alkaptonuria 
B)  sickle cell anemia and hemophilia 
C)  cystic fibrosis and Tay-Sachs disease 
D)  Huntington's disease and fragile X syndrome 
E)  cri du chat syndrome and Down syndrome 
A)  PKU and alkaptonuria 
B)  sickle cell anemia and hemophilia 
C)  cystic fibrosis and Tay-Sachs disease 
D)  Huntington's disease and fragile X syndrome 
E)  cri du chat syndrome and Down syndrome

Question 19

Match between columns
                        Premises: defect in the protein that regulates chloride transport across cell membranes

Accepted Answer

The Answer of hemophilia A and sickle cell anemia and is...

Question 20

Genome-wide association scans compare the proteins of individuals with a disease to individuals without the disease.

Accepted Answer

A) True 
 B)False

Exam 16: Human Genetics and the Human Genome

Compare the benefits and risks associated with amniocentesis and chorionic villus sampling.

Polyploidy is the:

Briefly illustrate how nondisjunction in meiosis can result in Down syndrome.

Hemophilia A is an example of a(n) _____ disease and is characterized by a lack of blood-clotting factor ____.

Discuss the necessity and benefits of the Genetic Information Nondiscrimination Act (GIN A) of 2008.

What are the predicted phenotypes of the children from a union of a woman who is heterozygous for hemophilia and a man who is normal? (Use the Punnett square to verify your answer.)

Down syndrome is an example of a ____ condition.

Figure 16-2 The genotypes of the normal females in the second generation in accompanying figure are:

The Human Genome Project was completed in 2012 and revealed a genomic map of 38 million SNPs.

The position of a specific gene on a chromosome can be determined by:

Karyotyping is useful for determining:

FISH distinguishes chromosomes by using more than one fluorescent-tagged RNA strand, which will bind to complementary DNA sequences on a specific chromosome.

Sickle cell anemia and cystic fibrosis are examples of a homozygote advantage.

What was revealed with the completion of the Human Genome Project?

Nondisjunction of the XY pair during the first meiotic division can produce sperm with 2 X chromosomes and 2 Y chromosomes.

Which of the following are inborn errors of metabolism?

Genome-wide association scans compare the proteins of individuals with a disease to individuals without the disease.

A View of Life

Atoms and Molecules: the Chemical Basis of Life

The Chemistry of Life: Organic Compounds

Organization of the Cell

Biological Membranes

Cell Communication

Energy and Metabolism

How Cells Make Atp: Energy-Releasing Pathways

Photosynthesis: Capturing Light Energy

Chromosomes, Mitosis, and Meiosis

The Basic Principles of Heredity

DNA: The Carrier of Genetic Information

Gene Expression

Gene Regulation

DNA Technology and Genomics

Developmental Genetics

Introduction to Darwinian Evolution

Evolutionary Change in Populations

Speciation and Macroevolution

The Origin and Evolutionary History of Life

The Evolution of Primates

Understanding Diversity: Systematics

Viruses and Subviral Agents

Bacteria and Archaea

Protists

Seedless Plants

Seed Plants

The Fungi

An Introduction to Animal Diversity

Sponges, Cnidarians, Ctenophores, and Protostomes

The Deuterostomes

Plant Structure, Growth, and Development

Leaf Structure and Function

Stem Structure and Transport

Roots and Mineral Nutrition

Reproduction in Flowering Plants

Plant Developmental Responses to External and Internal Signals

Animal Structure and Function: an Introduction

Protection, Support, and Movement

Neural Signaling

Neural Regulation

Sensory Systems

Internal Transport

The Immune System: Internal Defense

Gas Exchange

Processing Food and Nutrition

Osmoregulation and Disposal of Metabolic Wastes

Endocrine Regulation

Reproduction

Animal Development

Animal Behavior

Introduction to Ecology: Population Ecology

Community Ecology

Ecosystems and the Biosphere

Ecology and the Geography of Life

Biological Diversity and Conservation Biology

Filters

Hemophilia A is an example of a(n) _ disease and is characterized by a lack of blood-clotting factor .