Exam 22: Mammalian Fuel Metabolism: Integration and Regulation

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Aerobic activity in response to stress results in which of the following? I.Glycolysis occurs in the muscle. II.Glycolysis occurs in the liver. III.Glycogenolysis occurs in the muscle. IV.Glycogenolysis occurs in the liver.

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Matching Choose the correct answer from the list. Not all the answers will be used. -The endocrine glands secrete ______ which result in numerous cellular responses.

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Synthesis of triacylglycerols is dependent on

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Phospholipase C cleaves PIP2, generating

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Which of the following can generate glucose? I.kidney II.liver III.adipose tissue IV.muscle

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At low glucose concentrations (≤5mM), the majority of glucose produced by liver cells is due to the action of

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Matching Choose the correct answer from the list. Not all the answers will be used. -The activity of the _____ enzyme glucokinase increases with high blood glucose.

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The metabolic fate(s)of glucose-6-phosphate include I.glycogen and glucose. II.ribose-5-phosphate III.acetyl-CoA. IV.DNA and RNA.

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Animals lack the ability to produce glucose from ______.

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Matching Choose the correct answer from the list. Not all the answers will be used. -The ______ stores very little glycogen and therefore requires a steady supply of glucose from the blood.

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Which of the following are characteristics of metabolic syndrome? I.insulin resistance II.inflammation III.increased risk for type 1 diabetes. IV.hypersensitivity to insulin

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Excess glucosylation of lens proteins in diabetics leads to

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Evidence suggests that the lifespan of a rodent may be extended

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Matching Choose the correct answer from the list. Not all the answers will be used. -The ____ provides a pathway for the metabolic use of lactate for production of glucose.

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In an average individual the liver glycogen is depleted during starvation in approximately

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Which of the following best describes the function of AMP-dependent protein kinase (AMPK)?

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Matching Choose the correct answer from the list. Not all the answers will be used. -Epinephrine binding to the ______ causes an increase in intracellular [Ca2+].

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Which of the following statements concerning the response of hepatocytes to insulin is FALSE?

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The interorgan pathway that allows transport of nitrogen from muscle to the liver utilizes ____ as an amino group acceptor in the transamination reaction generating _____.

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Which of the following occurs during starvation? I.The kidney generates approximately half the glucose required for the body. II.The brain utilizes ketone bodies as a fuel source. III.The adipose tissue releases fatty acids. IV.Gluconeogenesis occurs in the liver.

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