Exam 28: Regulation of Gene Expression

Matching Choose the correct answer from the list. Not all the answers will be used. -The ______ proteins can undergo posttranslational modification by acetylation, phosphorylation, methylation, and ubiquitination.

Matching Choose the correct answer from the list. Not all the answers will be used. -RNAP II holoenzyme contains RNAP II and the protein complex called ______.

Of the human genome approximately 80% ___.

Gene regulation by the JAK-STAT pathway relays signals initiated by

Which of the following statements about repetitive DNA sequences is FALSE?

Which of the following best describes caspases?

How many nucleotide pairs does a bacterial genome typically contain?

Which of the following events are necessary for efficient expression of the lac operon? I.The lac repressor must bind inducer and dissociate from the operator site. II.CAP must bind cAMP. III.CAP and the repressor must simultaneously bind to RNAP.

Which of the following is correct regarding the function of the lac repressor protein?

Activators and repressors bind to target DNA sites called

The p53 protein functions as a ___ arresting the cell cycle in the ___ phase.

On average a single nucleotide polymorphism occurs ____ in humans.

How many nucleotide pairs does a mammalian genome typically contain?

Euchromatin is

In humans, approximately ______ of the genome encodes proteins.

In eukaryotic cells, methylated bases are present in palindromic ______, which are often found in upstream promoter regions.

Hormone response elements I.are DNA segments that contain repeated sequences separated by several bases. II.bind members of the nuclear receptor superfamily of proteins. III.are highly conserved sequences found in prokaryotic and eukaryotic cells.

Matching Choose the correct answer from the list. Not all the answers will be used. -Genes without a known function are called ______ genes.

What type of mutation causes conditions such as Huntington's disease and Fragile X syndrome?

A mutant strain of E.coli lacks a binding site for CAP at the promoter for the lac operon.How does expression of the operon compare to wild type? (The bold face row indicates units of activity observed in wild type.)