Exam 17: Citric Acid Cycle

Which of the following is TRUE regarding the discovery of the citric acid cycle? I.One of the first discoveries was the involvement of coenzyme A in the production of GTP. II.Krebs had knowledge of the sequence of reactions before he was able to demonstrate the link of the cycle to glucose metabolism. III.The citric acid cycle was the first cyclic pathway discovered. IV.Krebs demonstrated the involvement of the citric acid cycle in oxidation of amino acid and fatty acids.

Which of the following structures represents a molecule that is added to succinate to form CoA and malate?

Which of the following coenzymes is required by E₁ of the pyruvate dehydrogenase complex for catalytic activity?

Matching Choose the correct answer from the list. Not all the answers will be used. -The compound ______ is a structural analog and competitive inhibitor of the enzyme succinate dehydrogenase.

The reaction catalyzed by _____ requires an enzyme bound flavin coenzyme.

Which of the following can be said about the isocitrate product of aconitase?

Considering the reactions within the citric acid cycle, which of the following molecules will be produced from the intermediate pictured on the right?

Matching Choose the correct answer from the list. Not all the answers will be used. -The enzyme ______ is unique because it contains an iron-sulfur cluster but does not participate in a redox reaction.

The reaction catalyzed by pyruvate carboxylase is an example of a(n)______ reaction because it replenishes the citric acid cycle intermediates that have been siphoned off for use in other reactions.

Which of the following is oxidized by a multienzyme complex that requires five different coenzymes?