Exam 9: Lipids and Biological Membranes

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Which of the following correctly describes the usefulness of SNAREs? I.They are essential for proper post-translation processing. II.They are a critical element in the function of the secretory pathway. III.They are effective at overcoming electrostatic repulsion between vesicle membranes. IV.They facilitate anchoring between vesicle membranes.

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Which of the following structures correctly represents a glycerophospholipid? Which of the following structures correctly represents a glycerophospholipid?

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Sphingolipids I.contain a glycerol core with a phosphocholine headgroup. II.contain a modified sphingosine. III.often function as receptor components of membranes. IV.function as a precursor to sterols.

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Which of the following classes of proteins associates with the membrane bilayer with the lowest energy and would therefore be most difficult to separate from the membrane?

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Adipocytes

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Lung surfactants function to decrease the likelihood of collapse of the alveoli when air is expired.Based on your knowledge of lipids and amphipathic molecules, which of the following explains the mechanism by which the dipalmitoyl phosphatidylcholine (DPPC)can accomplish this task?

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Matching -Eicosanoids are 20-carbon compounds derived from ______.

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The signal peptide sequence I.is often used to direct proteins to the lysosome for incorporation into the lysosome. II.is usually not used for small eukaryotic proteins. III.of some transmembrane proteins is embedded into the membrane as an anchor. IV.is usually cleaved off the completed protein.

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A researcher is developing a new drug for the treatment of influenza.Based on the information presented in the text about the influenza virus, which of the following drug reactions describes the action of this new drug?

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Matching -A derivative of______ is the major lipid in lung surfactant.

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The _________ model describes the cell membrane as an assortment of integral proteins suspended freely in a lipid bilayer.

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In bacteria, phospholipids are synthesized:

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Rank the melting points of the following fatty acids from highest to lowest: (1)cis-oleic(18:1) (2)trans-oleic (18:1) (3)linoleic (18:2) (4)steraic (18:0) (5)palmitic (16:0)

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Transmembrane proteins I.are predominantly constructed of a single hydrophobic α-helix. II.are often constructed from bundles of hydrophobic β\beta -helices. III.are sometimes constructed from β-barrels with hydrophobic interiors and exteriors. IV.may have transmembrane helices identified by the free energy of transfer to water.

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Which of the following points to the correct location of attachment for a fatty acid which would yield a ceramide? Which of the following points to the correct location of attachment for a fatty acid which would yield a ceramide?

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A researcher has designed a new drug that will block the release of certain neurotransmitters from the synaptic cleft.Which of the following reactions must be blocked by this new drug?

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Matching -A steroid-derived hormone that must be activated by hydroxylation, ______ regulates Ca2+ metabolism.

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Triglycerides contain more metabolic energy per unit weight than glycogen because: I.Glycogen has greater polarity than fatty acids. II.Fatty acids predominate in an anhydrous form III.Fatty acids are less oxidized than carbohydrates. IV.Triglycerides have a higher average molecular mass.

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Which of the structures below is an example of an ω\omega -3 polyunsaturated fatty acid?  Which of the structures below is an example of an  \omega -3 polyunsaturated fatty acid?

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The _________, which is found embedded in the endoplasmic reticulum, is a _______ protein.

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