Question 1

Tropheryma whipplei is the causative agent for Whipple's disease. It could not be cultured until recently, when the genomic data showed that it

Accepted Answer

A)  was auxotrophic for some amino acids. 
B)  was an obligate intracellular pathogen. 
C)  needed a helper virus to grow. 
D)  needed high levels of iron. 
E)  is a virus that needs cell culture. 
A)  was auxotrophic for some amino acids. 
B)  was an obligate intracellular pathogen. 
C)  needed a helper virus to grow. 
D)  needed high levels of iron. 
E)  is a virus that needs cell culture.

Question 2

What characteristics of a pathogen distinguish it from a commensal, in terms of its ability to infect and replicate within a eukaryotic host?

Accepted Answer

Commensals are essentially relegated to

Question 3

The term used to designate how many bacteria or viruses are required to kill 50% of an experimental group of hosts is

Accepted Answer

A)  ID50. 
B)  LD50. 
C)  pathogenicity. 
D)  infectivity. 
E)  virulence. 
A)  ID50. 
B)  LD50. 
C)  pathogenicity. 
D)  infectivity. 
E)  virulence.

Question 4

Microbes can be transmitted indirectly from one person to another by inanimate objects, collectively called fomites. Describe the role of fomites in the spread of influenza.

Accepted Answer

The influenza virus can be spread by aer

Question 5

Describe what is happening at step 1 in the figure below.

Accepted Answer

There is a fusion be

Question 6

The disease filariasis, commonly known as elephantiasis, is caused by a(n)

Accepted Answer

A)  ectoparasite. 
B)  endoparasite. 
C)  insect. 
D)  bacterium. 
E)  fungus. 
A)  ectoparasite. 
B)  endoparasite. 
C)  insect. 
D)  bacterium. 
E)  fungus.

Question 7

Pathogenicity islands include all of the following EXCEPT that

Accepted Answer

A)  genes are not expressed as operons. 
B)  GC/AT ratio differs from the rest of the genome. 
C)  residual phage genomes flank the island. 
D)  they are often linked to tRNA. 
E)  they encode the type III protein secretion (T3SS) export systems. 
A)  genes are not expressed as operons. 
B)  GC/AT ratio differs from the rest of the genome. 
C)  residual phage genomes flank the island. 
D)  they are often linked to tRNA. 
E)  they encode the type III protein secretion (T3SS) export systems.

Question 8

Type I and Type IV pili both

Accepted Answer

A)  are similar in mode of secretion. 
B)  are mannose resistant. 
C)  have an assembly that does not involve the secA general secretory pathway. 
D)  are encoded by a pathogenicity island. 
E)  are exclusively used for pathogenesis. 
A)  are similar in mode of secretion. 
B)  are mannose resistant. 
C)  have an assembly that does not involve the secA general secretory pathway. 
D)  are encoded by a pathogenicity island. 
E)  are exclusively used for pathogenesis.

Question 9

Diphtheria toxin is a classic AB exotoxin. How does it cause host cell damage?

Accepted Answer

Diphtheria toxin is an AB toxin whose re

Question 10

An example of vertical transmission of infectious agents is

Accepted Answer

A)  Staphylococcus spp. gaining antibiotic resistance genes through conjugation. 
B)  HIV passing from mother to child in utero. 
C)  an infectious ameba obtained from a water sample. 
D)  influenza being passed by a sneeze. 
E)  hepatitis being transmitted by an infected needle stick. 
A)  Staphylococcus spp. gaining antibiotic resistance genes through conjugation. 
B)  HIV passing from mother to child in utero. 
C)  an infectious ameba obtained from a water sample. 
D)  influenza being passed by a sneeze. 
E)  hepatitis being transmitted by an infected needle stick.

Tropheryma whipplei is the causative agent for Whipple's disease. It could not be cultured until recently, when the genomic data showed that it

What characteristics of a pathogen distinguish it from a commensal, in terms of its ability to infect and replicate within a eukaryotic host?

The term used to designate how many bacteria or viruses are required to kill 50% of an experimental group of hosts is

Microbes can be transmitted indirectly from one person to another by inanimate objects, collectively called fomites. Describe the role of fomites in the spread of influenza.

Describe what is happening at step 1 in the figure below.

The disease filariasis, commonly known as elephantiasis, is caused by a(n)

Pathogenicity islands include all of the following EXCEPT that

Type I and Type IV pili both

Diphtheria toxin is a classic AB exotoxin. How does it cause host cell damage?

An example of vertical transmission of infectious agents is

Microbial Life: Origin and Discovery

Observing the Microbial Cell

Cell Structure and Function

Bacterial Culture, Growth, and Development

Environmental Influences and Control of Microbial Growth

Viruses

Genomes and Chromosomes

Transcription, Translation, and Bioinformatics

Gene Transfer, Mutations, and Genome Evolution

Molecular Regulation

Viral Molecular Biology

Biotechniques and Synthetic Biology

Energetics and Catabolism

Electron Flow in Organotrophy, Lithotrophy, and Phototrophy

Biosynthesis

Food and Industrial Microbiology

Origins and Evolution

Bacterial Diversity

Archaeal Diversity

Eukaryotic Diversity

Microbial Ecology

Microbes in Global Elemental Cycles

Human Microbiota and Innate Immunity

The Adaptive Immune Response

Microbial Diseases

Antimicrobial Therapy

Clinical Microbiology and Epidemiology

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Exam 25: Microbial Pathogenesis

Tropheryma whipplei is the causative agent for Whipple's disease. It could not be cultured until recently, when the genomic data showed that it

What characteristics of a pathogen distinguish it from a commensal, in terms of its ability to infect and replicate within a eukaryotic host?

The term used to designate how many bacteria or viruses are required to kill 50% of an experimental group of hosts is

Microbes can be transmitted indirectly from one person to another by inanimate objects, collectively called fomites. Describe the role of fomites in the spread of influenza.

Describe what is happening at step 1 in the figure below.

The disease filariasis, commonly known as elephantiasis, is caused by a(n)

Pathogenicity islands include all of the following EXCEPT that

Type I and Type IV pili both

Diphtheria toxin is a classic AB exotoxin. How does it cause host cell damage?

An example of vertical transmission of infectious agents is

Microbial Life: Origin and Discovery

Observing the Microbial Cell

Cell Structure and Function

Bacterial Culture, Growth, and Development

Environmental Influences and Control of Microbial Growth

Viruses

Genomes and Chromosomes

Transcription, Translation, and Bioinformatics

Gene Transfer, Mutations, and Genome Evolution

Molecular Regulation

Viral Molecular Biology

Biotechniques and Synthetic Biology

Energetics and Catabolism

Electron Flow in Organotrophy, Lithotrophy, and Phototrophy

Biosynthesis

Food and Industrial Microbiology

Origins and Evolution

Bacterial Diversity

Archaeal Diversity

Eukaryotic Diversity

Microbial Ecology

Microbes in Global Elemental Cycles

Human Microbiota and Innate Immunity

The Adaptive Immune Response

Microbial Diseases

Antimicrobial Therapy

Clinical Microbiology and Epidemiology

Filters