Question 1

The ____ is a functional region found in certain proteins that are important in development. It consists of 60 amino acids that form four helices.

Accepted Answer

A)  homeobox 
B)  homeodomain 
C)  homeogene 
D)  homeochromosome 
E)  functional group 
A)  homeobox 
B)  homeodomain 
C)  homeogene 
D)  homeochromosome 
E)  functional group

Question 2

Differential gene expression is defined as the:

Accepted Answer

A)  ability of some cells to arrest their development under varying environmental conditions. 
B)  progressive fixation of the fates of a cell's descendants. 
C)  genetic variation found in various somatic cells of the same individual. 
D)  regulation during development that varies the type and quantity of gene products among cells. 
E)  constitutive expression of all genes in the somatic cells. 
A)  ability of some cells to arrest their development under varying environmental conditions. 
B)  progressive fixation of the fates of a cell's descendants. 
C)  genetic variation found in various somatic cells of the same individual. 
D)  regulation during development that varies the type and quantity of gene products among cells. 
E)  constitutive expression of all genes in the somatic cells.

Question 3

Briefly discuss how homeobox transcription factors and genes-containing homeodomains affect development.

Accepted Answer

Some genes that code for transcription f

Question 4

The fact that most segmentation genes code for ____ indicates that these protein products are ____ that regulate the expression of other genes.

Accepted Answer

A)  homeobox genes; genetic switches 
B)  transcription factors; genetic switches 
C)  transcription factors; inducers 
D)  maternal effect genes; protein switches 
E)  hormones; signaling molecules 
A)  homeobox genes; genetic switches 
B)  transcription factors; genetic switches 
C)  transcription factors; inducers 
D)  maternal effect genes; protein switches 
E)  hormones; signaling molecules

Question 5

You would not expect to find homeobox or homeobox-like genes in:

Accepted Answer

A)  Drosophila 
B)  Arabidopsis 
C)  C. elegans 
D)  H. sapiens 
E)  E. coli 
A)  Drosophila 
B)  Arabidopsis 
C)  C. elegans 
D)  H. sapiens 
E)  E. coli

Question 6

Imaginal discs are:

Accepted Answer

A)  found in mammalian cells and control gene activation in mature somatic cells 
B)  paired groups of undifferentiated cells that are precursors of adult structures in Drosophila 
C)  found in plant cells and assist in the development of the flower 
D)  part of the salivary gland of Drosophila 
E)  found in Drosophila ovary cells and represent inactivated X chromosomes 
A)  found in mammalian cells and control gene activation in mature somatic cells 
B)  paired groups of undifferentiated cells that are precursors of adult structures in Drosophila 
C)  found in plant cells and assist in the development of the flower 
D)  part of the salivary gland of Drosophila 
E)  found in Drosophila ovary cells and represent inactivated X chromosomes

Question 7

During the course of development, unspecialized cells become more committed to a specific fate.

Accepted Answer

A) True 
 B)False

Question 8

Ras is a tumor suppressor gene that is mutated in cases of familial breast cancer.

Accepted Answer

A) True 
 B)False

Question 9

Match between columns
                        Premises: apoptosis

Accepted Answer

The Answer of D. melanogaster and M. musculus and C. is...

Question 10

RNA interference is used to:

Accepted Answer

A)  interfere with specific transcription factors. 
B)  knock out the expression of a specific gene. 
C)  prevent the duplication of DNA. 
D)  cause a mutation in a specific gene. 
E)  stimulate apoptosis. 
A)  interfere with specific transcription factors. 
B)  knock out the expression of a specific gene. 
C)  prevent the duplication of DNA. 
D)  cause a mutation in a specific gene. 
E)  stimulate apoptosis.

Question 11

One of the main obstacles to successful cloning of sheep, apparently overcome by Wilmut et al., was:

Accepted Answer

A)  to find an adult nucleus that was likely to work. 
B)  to synchronize the cell cycles of the donor cell and the egg cell. 
C)  to enucleate the donor cell. 
D)  the ability to culture cells in the laboratory. 
E)  to recognize that the nucleus from one sheep cell may contain different genetic information than the nucleus of another cell from the same animal. 
A)  to find an adult nucleus that was likely to work. 
B)  to synchronize the cell cycles of the donor cell and the egg cell. 
C)  to enucleate the donor cell. 
D)  the ability to culture cells in the laboratory. 
E)  to recognize that the nucleus from one sheep cell may contain different genetic information than the nucleus of another cell from the same animal.

Question 12

Malignant tumors are characterized by:

Accepted Answer

A)  metastasis 
B)  abnormal cell growth 
C)  the formation of cell masses 
D)  specific mutations 
E)  proto-oncogenes 
A)  metastasis 
B)  abnormal cell growth 
C)  the formation of cell masses 
D)  specific mutations 
E)  proto-oncogenes

Question 13

____ are organisms that contain two or more kinds of genetically dissimilar cells from different zygotes.

Accepted Answer

A)  Heterozygotes 
B)  Chimeras 
C)  Recombinants 
D)  Transgenics 
E)  Polyploids 
A)  Heterozygotes 
B)  Chimeras 
C)  Recombinants 
D)  Transgenics 
E)  Polyploids

Question 14

The concept of nuclear equivalence states that:

Accepted Answer

A)  all of the somatic cells in an adult organism have the same genes. 
B)  the genes of the individuals of the same species are exactly the same. 
C)  as cells mature, unneeded genes are lost. 
D)  the nuclei of all organisms are the same. 
E)  nuclei of individuals of the same species are the same size. 
A)  all of the somatic cells in an adult organism have the same genes. 
B)  the genes of the individuals of the same species are exactly the same. 
C)  as cells mature, unneeded genes are lost. 
D)  the nuclei of all organisms are the same. 
E)  nuclei of individuals of the same species are the same size.

Question 15

Maternal effect genes of Drosophila are genes active in ____ cells, whose products establish ____ in developing embryos.

Accepted Answer

A)  maternal; gender 
B)  maternal; polarity 
C)  embryonic; polarity 
D)  embryonic; gender 
E)  egg; gender 
A)  maternal; gender 
B)  maternal; polarity 
C)  embryonic; polarity 
D)  embryonic; gender 
E)  egg; gender

Question 16

One way RNA interference molecules work is by selectively cleaving DNA molecules that have sequences complementary to small RNA molecules.

Accepted Answer

A) True 
 B)False

Question 17

Match between columns
                        Premises: Step 1

Accepted Answer

The Answer of take in vitro culture of embryo and is...

Question 18

What characteristics of Drosophila melanogaster make it useful in molecular genetics studies?

Accepted Answer

Concepts to Consider: Drosophi

Question 19

The only known source of human embryonic stem cells is:

Accepted Answer

A)  placental tissue 
B)  umbilical cords 
C)  early human embryos 
D)  brain tissue 
E)  nerve tissue 
A)  placental tissue 
B)  umbilical cords 
C)  early human embryos 
D)  brain tissue 
E)  nerve tissue

Question 20

Figure 17-12
 
The mutation labeled as 1 to the far right in the accompanying figure represents:

Accepted Answer

A)  legs developing where antenna should be 
B)  appendages of the eyes 
C)  enlarged antennae 
D)  newly formed structures to remove pollen or dust from the eyes 
E)  a revision of the fly body so that legs and antenna have switched places 
A)  legs developing where antenna should be 
B)  appendages of the eyes 
C)  enlarged antennae 
D)  newly formed structures to remove pollen or dust from the eyes 
E)  a revision of the fly body so that legs and antenna have switched places

Exam 17: Developmental Genetics

The ____ is a functional region found in certain proteins that are important in development. It consists of 60 amino acids that form four helices.

Differential gene expression is defined as the:

Briefly discuss how homeobox transcription factors and genes-containing homeodomains affect development.

The fact that most segmentation genes code for ____ indicates that these protein products are ____ that regulate the expression of other genes.

You would not expect to find homeobox or homeobox-like genes in:

Imaginal discs are:

During the course of development, unspecialized cells become more committed to a specific fate.

Ras is a tumor suppressor gene that is mutated in cases of familial breast cancer.

RNA interference is used to:

One of the main obstacles to successful cloning of sheep, apparently overcome by Wilmut et al., was:

Malignant tumors are characterized by:

____ are organisms that contain two or more kinds of genetically dissimilar cells from different zygotes.

The concept of nuclear equivalence states that:

Maternal effect genes of Drosophila are genes active in ____ cells, whose products establish ____ in developing embryos.

One way RNA interference molecules work is by selectively cleaving DNA molecules that have sequences complementary to small RNA molecules.

What characteristics of Drosophila melanogaster make it useful in molecular genetics studies?

The only known source of human embryonic stem cells is:

Figure 17-12 The mutation labeled as 1 to the far right in the accompanying figure represents:

A View of Life

Atoms and Molecules: the Chemical Basis of Life

The Chemistry of Life: Organic Compounds

Organization of the Cell

Biological Membranes

Cell Communication

Energy and Metabolism

How Cells Make Atp: Energy-Releasing Pathways

Photosynthesis: Capturing Light Energy

Chromosomes, Mitosis, and Meiosis

The Basic Principles of Heredity

DNA: The Carrier of Genetic Information

Gene Expression

Gene Regulation

DNA Technology and Genomics

Human Genetics and the Human Genome

Introduction to Darwinian Evolution

Evolutionary Change in Populations

Speciation and Macroevolution

The Origin and Evolutionary History of Life

The Evolution of Primates

Understanding Diversity: Systematics

Viruses and Subviral Agents

Bacteria and Archaea

Protists

Seedless Plants

Seed Plants

The Fungi

An Introduction to Animal Diversity

Sponges, Cnidarians, Ctenophores, and Protostomes

The Deuterostomes

Plant Structure, Growth, and Development

Leaf Structure and Function

Stem Structure and Transport

Roots and Mineral Nutrition

Reproduction in Flowering Plants

Plant Developmental Responses to External and Internal Signals

Animal Structure and Function: an Introduction

Protection, Support, and Movement

Neural Signaling

Neural Regulation

Sensory Systems

Internal Transport

The Immune System: Internal Defense

Gas Exchange

Processing Food and Nutrition

Osmoregulation and Disposal of Metabolic Wastes

Endocrine Regulation

Reproduction

Animal Development

Animal Behavior

Introduction to Ecology: Population Ecology

Community Ecology

Ecosystems and the Biosphere

Ecology and the Geography of Life

Biological Diversity and Conservation Biology

Filters

The fact that most segmentation genes code for indicates that these protein products are that regulate the expression of other genes.

Maternal effect genes of Drosophila are genes active in cells, whose products establish in developing embryos.