Question 1

Multiple myeloma can be defined as a neoplasm of:

Accepted Answer

A)  T cells. 
B)  B cells. 
C)  immature plasma cells. 
D)  mature red blood cells. 
A)  T cells. 
B)  B cells. 
C)  immature plasma cells. 
D)  mature red blood cells.

Question 2

A 35-year-old male with hyperthyroidism begins treatment to decrease thyroid activity. Which of the following could result secondary to the treatment?

Accepted Answer

A)  Eosinophilia 
B)  Basophilia 
C)  Monocytosis 
D)  Lymphocytosis 
A)  Eosinophilia 
B)  Basophilia 
C)  Monocytosis 
D)  Lymphocytosis

Question 3

A 25-year-old female has a heavy menses during which she loses a profuse amount of blood. Which of the following adaptations could be expected?

Accepted Answer

A)  Movement of fluid into the cell 
B)  Decreased cardiac output 
C)  Decreased oxygen release from hemoglobin 
D)  Blood vessel dilation 
A)  Movement of fluid into the cell 
B)  Decreased cardiac output 
C)  Decreased oxygen release from hemoglobin 
D)  Blood vessel dilation

Question 4

A 45-year-old male is diagnosed with pernicious anemia. The most likely cause of this condition is:

Accepted Answer

A)  defective DNA synthesis. 
B)  abnormal synthesis of hemoglobin. 
C)  defective use of vitamin C. 
D)  blocked protein synthesis. 
A)  defective DNA synthesis. 
B)  abnormal synthesis of hemoglobin. 
C)  defective use of vitamin C. 
D)  blocked protein synthesis.

Question 5

A 2-year-old malnourished child has vitamin B12 and folate deficiencies. A blood smear would reveal _____ amounts of hemoglobin.

Accepted Answer

A)  normal 
B)  sporadic 
C)  low 
D)  high 
A)  normal 
B)  sporadic 
C)  low 
D)  high

Question 6

Thrombocytopenia is described as a platelet count below _____ platelets per cubic millimeter.

Accepted Answer

A)  1,000,000 
B)  150,000 
C)  10,000 
D)  1000 
A)  1,000,000 
B)  150,000 
C)  10,000 
D)  1000

Question 7

A 15-year-old male is diagnosed with infectious mononucleosis. He most likely presented with the classic triad of symptoms: fever, sore throat, and:

Accepted Answer

A)  lymph node enlargement. 
B)  hepatitis. 
C)  rash on the trunk and extremities. 
D)  dyspnea. 
A)  lymph node enlargement. 
B)  hepatitis. 
C)  rash on the trunk and extremities. 
D)  dyspnea.

Question 8

The sequence of events in disseminated intravascular coagulation (DIC) is initiated by the release of:

Accepted Answer

A)  histamine. 
B)  fibrin. 
C)  tissue factor. 
D)  plasmin. 
A)  histamine. 
B)  fibrin. 
C)  tissue factor. 
D)  plasmin.

Question 9

A 50-year-old female was diagnosed with sideroblastic anemia. Which of the following would most likely occur?

Accepted Answer

A)  Pale skin 
B)  Iron overload 
C)  Normochromic erythrocytes 
D)  Aplastic bone marrow 
A)  Pale skin 
B)  Iron overload 
C)  Normochromic erythrocytes 
D)  Aplastic bone marrow

Question 10

A 15-year-old male with infectious mononucleosis is being given instructions on how to prevent the spread of this infection to others. Which statement represents a correct instruction?

Accepted Answer

A)  Wear a surgical mask when others are in the room. 
B)  Do not share drinking glasses or eating utensils. 
C)  Avoid all contact with other people. 
D)  No precautions are necessary. 
A)  Wear a surgical mask when others are in the room. 
B)  Do not share drinking glasses or eating utensils. 
C)  Avoid all contact with other people. 
D)  No precautions are necessary.

Question 11

A 58-year-old female presents in the clinic with complaints of fatigue, weight loss, and tingling in her fingers. Laboratory findings show a low hemoglobin and hematocrit, a high mean corpuscular volume, and normal plasma iron. These findings are consistent with which type of anemia?

Accepted Answer

A)  Hemolytic anemia 
B)  Pernicious anemia 
C)  Iron deficiency anemia 
D)  Aplastic anemia 
A)  Hemolytic anemia 
B)  Pernicious anemia 
C)  Iron deficiency anemia 
D)  Aplastic anemia

Question 12

A 40-year-old female develops disseminated intravascular coagulation (DIC). The most likely cause of this condition is:

Accepted Answer

A)  snake venom. 
B)  blood transfusion. 
C)  sepsis. 
D)  immune thrombocytopenic purpura (ITP). 
A)  snake venom. 
B)  blood transfusion. 
C)  sepsis. 
D)  immune thrombocytopenic purpura (ITP).

Question 13

Which of the following individuals is at highest risk for developing a vitamin B12 deficiency anemia?

Accepted Answer

A)  47-year-old male who had a gastrectomy procedure (removal of the stomach) 
B)  64-year-old male with a history of duodenal ulcers and gastrointestinal bleeding 
C)  26-year-old female in the second trimester of her first pregnancy 
D)  3-year-old female who is a fussy eater 
A)  47-year-old male who had a gastrectomy procedure (removal of the stomach) 
B)  64-year-old male with a history of duodenal ulcers and gastrointestinal bleeding 
C)  26-year-old female in the second trimester of her first pregnancy 
D)  3-year-old female who is a fussy eater

Question 14

What hemodynamic change occurs after initial compensation for a reduction in the number of circulating erythrocytes?

Accepted Answer

A)  Increased viscosity of blood 
B)  Decreased cardiac output 
C)  Altered coagulation 
D)  Hyperdynamic blood flow 
A)  Increased viscosity of blood 
B)  Decreased cardiac output 
C)  Altered coagulation 
D)  Hyperdynamic blood flow

Question 15

Individuals with liver disease often suffer from coagulation disorders because:

Accepted Answer

A)  the liver is often the site of platelet pooling. 
B)  clotting factors are produced in the liver. 
C)  high levels of bilirubin interfere with the clotting system. 
D)  treatment medications for liver failure cause fibrinolysis. 
A)  the liver is often the site of platelet pooling. 
B)  clotting factors are produced in the liver. 
C)  high levels of bilirubin interfere with the clotting system. 
D)  treatment medications for liver failure cause fibrinolysis.

Question 16

A 60-year-old female emphysema patient experiences a rapid and pounding heart, dizziness, and fatigue with exertion. How would the respiratory system compensate for the increased oxygen demand?

Accepted Answer

A)  Bronchoconstriction 
B)  Increased rate and depth of breathing 
C)  Dyspnea 
D)  Activation of the renin-angiotensin response 
A)  Bronchoconstriction 
B)  Increased rate and depth of breathing 
C)  Dyspnea 
D)  Activation of the renin-angiotensin response

Question 17

Which of the following tests directly measures iron stores?

Accepted Answer

A)  Serum ferritin 
B)  Transferrin saturation 
C)  Bone marrow biopsy 
D)  Total iron-binding capacity 
A)  Serum ferritin 
B)  Transferrin saturation 
C)  Bone marrow biopsy 
D)  Total iron-binding capacity

Question 18

A 50-year-old female is diagnosed with primary thrombocythemia. A blood smear reveals _____ platelets.

Accepted Answer

A)  defective 
B)  fragmented 
C)  consumed 
D)  overproduced 
A)  defective 
B)  fragmented 
C)  consumed 
D)  overproduced

Question 19

A 67-year-old female is admitted to the emergency room with a diagnosis of polycythemia vera. She will most likely complain of:

Accepted Answer

A)  hyperactivity. 
B)  decreased blood pressure. 
C)  chest pain. 
D)  a pale skin color. 
A)  hyperactivity. 
B)  decreased blood pressure. 
C)  chest pain. 
D)  a pale skin color.

Question 20

Leukocytosis can be defined as:

Accepted Answer

A)  a normal leukocyte count. 
B)  a high leukocyte count. 
C)  a low leukocyte count. 
D)  another term for leukopenia. 
A)  a normal leukocyte count. 
B)  a high leukocyte count. 
C)  a low leukocyte count. 
D)  another term for leukopenia.

Exam 20: Alterations of Hematologic Function

Multiple myeloma can be defined as a neoplasm of:

A 35-year-old male with hyperthyroidism begins treatment to decrease thyroid activity. Which of the following could result secondary to the treatment?

A 25-year-old female has a heavy menses during which she loses a profuse amount of blood. Which of the following adaptations could be expected?

A 45-year-old male is diagnosed with pernicious anemia. The most likely cause of this condition is:

A 2-year-old malnourished child has vitamin B12 and folate deficiencies. A blood smear would reveal _____ amounts of hemoglobin.

Thrombocytopenia is described as a platelet count below _____ platelets per cubic millimeter.

A 15-year-old male is diagnosed with infectious mononucleosis. He most likely presented with the classic triad of symptoms: fever, sore throat, and:

The sequence of events in disseminated intravascular coagulation (DIC) is initiated by the release of:

A 50-year-old female was diagnosed with sideroblastic anemia. Which of the following would most likely occur?

A 15-year-old male with infectious mononucleosis is being given instructions on how to prevent the spread of this infection to others. Which statement represents a correct instruction?

A 58-year-old female presents in the clinic with complaints of fatigue, weight loss, and tingling in her fingers. Laboratory findings show a low hemoglobin and hematocrit, a high mean corpuscular volume, and normal plasma iron. These findings are consistent with which type of anemia?

A 40-year-old female develops disseminated intravascular coagulation (DIC). The most likely cause of this condition is:

Which of the following individuals is at highest risk for developing a vitamin B12 deficiency anemia?

What hemodynamic change occurs after initial compensation for a reduction in the number of circulating erythrocytes?

Individuals with liver disease often suffer from coagulation disorders because:

A 60-year-old female emphysema patient experiences a rapid and pounding heart, dizziness, and fatigue with exertion. How would the respiratory system compensate for the increased oxygen demand?

Which of the following tests directly measures iron stores?

A 50-year-old female is diagnosed with primary thrombocythemia. A blood smear reveals _____ platelets.

A 67-year-old female is admitted to the emergency room with a diagnosis of polycythemia vera. She will most likely complain of:

Leukocytosis can be defined as:

Cellular Biology

Genes and Genetic Diseases

Altered Cellular and Tissue Biology

Fluids and Electrolytes, Acids and Bases

Innate Defenses: Inflammation

Adaptive Immunity

Hypersensitivities, Infection, and Immune Deficiencies

Stress and Disease

Biology of Cancer and Tumor Spread

Cancer Epidemiology, Manifestations, and Treatment

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature, Sleep, and Sensory Function

Concepts of Neurologic Dysfunction

Alterations of Neurologic Function

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Hematologic System

Alterations of Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Reproductive Systems

Alterations of the Reproductive Systems, Including Sexually Transmitted Infections

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Filters

A 2-year-old malnourished child has vitamin B₁₂ and folate deficiencies. A blood smear would reveal _____ amounts of hemoglobin.

Which of the following individuals is at highest risk for developing a vitamin B₁₂ deficiency anemia?