Exam 17: Fatty Acid Catabolism

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The following fatty acid, in which the indicated carbon is labeled with 14C, is fed to an animal: 14CH3(CH2)9COOH After allowing 30 minutes for fatty acid β\beta oxidation, the label would MOST likely be recovered in:

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Describe the steps in the metabolic pathway in which cells oxidize a four-carbon, straight-chain, saturated fatty acid (butyrate; 4:0) to the fragments that enter the citric acid cycle. Show the structures of intermediates and products, and indicate where any cofactor(s) participate(s).

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Indicate whether the following statement is likely true or false, and explain your answer. After a breakfast rich in fat and very low in carbohydrates, acetyl CoA levels rise and ketone body synthesis decreases.

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Which statement about lipolysis in adipocytes is FALSE?

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Fatty acids are activated to acyl-CoAs and the acyl group is further transferred to carnitine because:

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Describe the steps in the metabolic pathway in which cells oxidize a five-carbon, straight-chain, saturated fatty acid (valerate; 5:0) to the fragments that enter the citric acid cycle. Show the structures of intermediates and products, and indicate where any cofactor(s) participate(s).

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Carnitine is:

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Various irreversible reactions "drive" processes bioenergetically. What is one such driving force leading to the formation of an acyl-CoA molecule?

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How many molecules of water are produced by the electron-transport chain during the complete aerobic oxidation of 1 molecule of palmitate?

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In the liver, which enzyme is NOT required in the catabolism of glycerol?

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If the fatty acid 12:1 Δ\Delta 7 is completely catabolized to CO2 and H2O, what would be the gross yield of ATP?

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Saturated fatty acids are degraded by the stepwise reactions of β\beta oxidation, producing acetyl-CoA. Under aerobic conditions, how many ATP molecules would be produced as a consequence of removal of each acetyl-CoA?

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Which enzyme is the major regulatory control point for β\beta oxidation?

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Which statement is TRUE regarding the regulation of β\beta oxidation?

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The consumption of palmitoyl-CoA by β\beta oxidation is decreased under which conditions?

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Transport of fatty acids from the cytoplasm to the mitochondrial matrix requires:

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The major site of formation of acetoacetate from fatty acids is the:

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What is the CORRECT order of function of the following enzymes of  oxidation? 1. -hydroxyacyl-CoA dehydrogenase 2. thiolase 3. enoyl-CoA hydratase 4. acyl-CoA dehydrogenase

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The metabolite that regulates the activity of carnitine acyl transferase I is:

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Which statement is TRUE regarding fatty acids in adipocytes?

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