Exam 6: Protein Function

Describe the two functional units of myoglobin that are responsible for O₂ binding.Include the type of chemical bond involved for each binding interaction (i.e.,hydrogen bond,covalent bond,electrostatic bond,etc.).

Below is a fractional saturation curve for O₂ binding to adult hemoglobin.Assume that curve Y represents a system at pH 7.4 and with a normal physiological level of 2,3-BPG.Curve X represents a system that

When oxygen binds to hemoglobin,which of the following occurs?

Which of the following is true of this compound?

The fractional saturation of hemoglobin (Hb)binding to oxygen is illustrated by

After __________ induced changes in the structure of thin filament,myosin heads containing __________ in the nucleotide binding site will bind with high affinity to actin subunits.

Which of the following is NOT a definition of fractional saturation for a system of [P] +[L] [PL]?

A passive transporter is discovered that can transport both galactose and glucose.The pore of the transporter can accommodate a single sugar at a time.If the extracellular concentrations of galactose and glucose are 0.2 and 3.6 mM,respectively,and the intracellular concentrations are 0.39 and 2.6 mM,respectively,which sugar is most likely to enter the cell through the transporter? Provide two reasons for your answer.

Which of the following would shift the oxygen binding curve for hemoglobin to the left?

The figure below shows the oxygen binding curves of oxygen-transport protein from four different organisms.Decide which organism is the most efficient at oxygen transport and justify your choice.

Which of the following may result from a His143 Ala143 mutation in adult hemoglobin?

A mutation in the subunit of hemoglobin is discovered that reduces the affinity of 2,3-BPG binding.Which of the following mutations is most likely to have this consequence?

Titin functions to connect __________ to __________.