Exam 36: Aerosol Drug Therapy

What serious problems associated with the delivery of ribavirin (Virazole) using the small-particle aerosol generator (SPAG)? I.caregiver exposure to the drug aerosol II.drug reconcentration in the drying chamber III.drug precipitation in ventilator circuits

Immediately after firing, the aerosol particles produced by most metered-dose inhalers are about how large?

What term describes the primary mechanism for deposition of small particles?

What is the best way to confirm that an asthmatic outpatient can properly self-manage a newly prescribed aerosol drug therapy?

What is the recommended dosage for continuous bronchodilator therapy (CBT)?

This problem of ribavirin (Virazole) aerosol precipitation causing malfunction of ventilator circuits can be overcome by which of the following? I.Placing a one-way valve between the small-particle aerosol generator (SPAG) and the circuit II.Placing a HEPA filter proximal to the exhalation valve III.Decreasing the SPAG's total flow to below 10 L/min

Where do most aerosol particles in the 1- to 5- $\mu$ m range deposit?

All of the following drugs or drug categories have been associated with increased airway resistance and bronchospasm during aerosol administration except:

What schedule of peak expiratory flow rate assessment would you recommend for a home care asthmatic patient?

What happens as the pressure or flow delivered through a small-volume jet nebulizer gets higher? I. Treatment time becomes shorter. II. Particle size becomes smaller. III. Aerosol output becomes greater.

You increase the fill volume from 2 to 4 ml in a small-volume jet nebulizer being used to administer a bronchodilator agent with an aerosol. What effect will this have on the amount of drug delivered?

What is the process by which aerosol suspension changes over time?

For maintenance administration of bronchodilators to an adult patient with adequate inspiratory flow, which of the following aerosol drug delivery devices would you recommend? I.pressurized metered-dose inhaler (pMDI)II.small-volume jet nebulizer III.dry powder inhaler IV.pMDI and holding chamber

Which of the following groups of patients are most likely to have difficulty using a simple metered-dose inhaler for aerosol drug therapy? I.patients in acute distress II.infants and young children III.elderly persons

To decrease the likelihood of an opportunistic yeast or fungal infection associated with metered-dose inhaler (MDI) steroids, what would you recommend that a patient do? I. Cut in half the number of puffs or treatments. II. Use a spacer or holding chamber. III. Rinse the mouth after each treatment.

In selecting the appropriate aerosol drug delivery device for a given patient, what must you consider? I.available drug formulation(s)II.desired site of deposition III.patient's characteristics IV.patient's preference

Which of the following is a common method to measure aerosol particle size?

The mass of aerosol particles produced by a nebulizer in a given unit time best describes which quality of the aerosol?

Advantages of the dry power inhaler (DPI) drug delivery systems include all of the following except:

When using a metered-dose inhaler without a holding chamber or a spacer, the patient should be instructed to fire the device at what point?