Question 1

Anti-human antibodies (specific for human IgG antibodies) with fluorescent molecules covalently attached are used for

Accepted Answer

A)  direct fluorescent antibody tests. 
B)  indirect fluorescent antibody tests. 
C)  direct ELISAs. 
D)  indirect ELISAs. 
E)  immunodiffusion tests. 
A)  direct fluorescent antibody tests. 
B)  indirect fluorescent antibody tests. 
C)  direct ELISAs. 
D)  indirect ELISAs. 
E)  immunodiffusion tests.

Question 2

Agglutination tests are used to detect soluble antigens.

Accepted Answer

A) True 
 B)False

Question 3

The assay represented in Figure 17.2 is used to

Accepted Answer

A)  detect antigen-specific antibodies in patient serum. 
B)  detect specific antigen in patient serum. 
C)  determine the titer of IgM in patient serum. 
D)  determine the presence of an antibody-modifying enzyme in a patient sample. 
E)  detect cytopathic effects of viral infection. 
A)  detect antigen-specific antibodies in patient serum. 
B)  detect specific antigen in patient serum. 
C)  determine the titer of IgM in patient serum. 
D)  determine the presence of an antibody-modifying enzyme in a patient sample. 
E)  detect cytopathic effects of viral infection.

Question 4

Which of the following tests does NOT detect an immune response to a virus infection?

Accepted Answer

A)  a viral neutralization test 
B)  a direct immunofluorescent antibody test 
C)  a viral hemagglutination test 
D)  a complement fixation test 
E)  a direct ELISA 
A)  a viral neutralization test 
B)  a direct immunofluorescent antibody test 
C)  a viral hemagglutination test 
D)  a complement fixation test 
E)  a direct ELISA

Question 5

Fluorescent antibody, ELISA, and immunoblotting tests involve the use of (hybridoma/labeled/unlabeled) antibodies.

Accepted Answer

The answer of Fluorescent antibody, ELISA, and immunoblotting tests involve...

Question 6

The MMR (measles, mumps, rubella) vaccine requires multiple immunizations in the first year because it is composed of whole killed viruses.

Accepted Answer

A) True 
 B)False

Question 7

Infection with the fungus Coccidioides immitis is commonly diagnosed using a(n) ________ assay.

Accepted Answer

A)  precipitation 
B)  immunoblot 
C)  direct fluorescent antibody 
D)  hemagglutination inhibition 
E)  neutralization 
A)  precipitation 
B)  immunoblot 
C)  direct fluorescent antibody 
D)  hemagglutination inhibition 
E)  neutralization

Question 8

Which of the following statements regarding an inactivated vaccine is FALSE?

Accepted Answer

A)  It can be produced with deactivated whole microorganisms. 
B)  It can be produced from antigenic fragments of a pathogen. 
C)  It is safer than an attenuated vaccine. 
D)  It is made from mutated forms of the pathogen. 
E)  It is made from pathogens that cannot replicate. 
A)  It can be produced with deactivated whole microorganisms. 
B)  It can be produced from antigenic fragments of a pathogen. 
C)  It is safer than an attenuated vaccine. 
D)  It is made from mutated forms of the pathogen. 
E)  It is made from pathogens that cannot replicate.

Question 9

Infection with HIV is routinely verified using a(n) ________ assay.

Accepted Answer

A)  direct fluorescent antibody 
B)  immunodiffusion precipitation 
C)  viral neutralization 
D)  viral hemagglutination inhibition 
E)  immunoblot 
A)  direct fluorescent antibody 
B)  immunodiffusion precipitation 
C)  viral neutralization 
D)  viral hemagglutination inhibition 
E)  immunoblot

Question 10

A woman uses a home pregnancy test kit that tests for hCG hormone in urine. She knows this is a type of antibody assay from the kit brochure. Antibodies reacting with the hormone produce two lines on the test strip. What specific type of antibody assay does this represent?

Accepted Answer

A)  a direct immunofluoresence test 
B)  a complement fixation test 
C)  an immunochromatographic assay 
D)  an ELISA 
E)  a neutralization assay 
A)  a direct immunofluoresence test 
B)  a complement fixation test 
C)  an immunochromatographic assay 
D)  an ELISA 
E)  a neutralization assay

Question 11

a person who has been exposed to rabies receives both HRIG (human rabies immunoglobulin) injected near the bite site and the rabies vaccine. What does this strategy represent?

Accepted Answer

A)  active immunization 
B)  passive immunotherapy 
C)  viral hemagglutination inhibition 
D)  passive immunotherapy combined with viral hemagglutination inhibition 
E)  active immunization combined with passive immunotherapy 
A)  active immunization 
B)  passive immunotherapy 
C)  viral hemagglutination inhibition 
D)  passive immunotherapy combined with viral hemagglutination inhibition 
E)  active immunization combined with passive immunotherapy

Question 12

Contact immunity within a population can be produced by ________ vaccines.

Accepted Answer

A)  attenuated 
B)  DNA 
C)  inactivated 
D)  subunit 
E)  toxoid 
A)  attenuated 
B)  DNA 
C)  inactivated 
D)  subunit 
E)  toxoid

Question 13

Infection with influenzavirus is commonly diagnosed using

Accepted Answer

A)  an immunoblot assay. 
B)  viral neutralization tests. 
C)  immunochromatographic assay. 
D)  viral hemagglutination inhibition test. 
E)  both immunochromatographic assay and viral hemagglutination inhibition test. 
A)  an immunoblot assay. 
B)  viral neutralization tests. 
C)  immunochromatographic assay. 
D)  viral hemagglutination inhibition test. 
E)  both immunochromatographic assay and viral hemagglutination inhibition test.

Question 14

The attenuated oral poliovirus vaccine (OVP) is no longer administered in the U.S.A. because it

Accepted Answer

A)  is very toxic. 
B)  does not provide good immunity. 
C)  can revert to wild-type virulence. 
D)  can be spread to contacts. 
E)  can be spread to contacts and can revert to wild-type virulence. 
A)  is very toxic. 
B)  does not provide good immunity. 
C)  can revert to wild-type virulence. 
D)  can be spread to contacts. 
E)  can be spread to contacts and can revert to wild-type virulence.

Question 15

The assay shown in Figure 17.1 is used for what?

Accepted Answer

A)  detecting antibodies against a complex mix of antigens 
B)  verifying infection with a virus 
C)  determining the concentration of antibodies 
D)  detecting neutralizing antibodies 
E)  blood typing 
A)  detecting antibodies against a complex mix of antigens 
B)  verifying infection with a virus 
C)  determining the concentration of antibodies 
D)  detecting neutralizing antibodies 
E)  blood typing

Exam 17: Immunization and Immune Testing

Anti-human antibodies (specific for human IgG antibodies) with fluorescent molecules covalently attached are used for

Agglutination tests are used to detect soluble antigens.

The assay represented in Figure 17.2 is used to

Which of the following tests does NOT detect an immune response to a virus infection?

Fluorescent antibody, ELISA, and immunoblotting tests involve the use of (hybridoma/labeled/unlabeled) antibodies.

The MMR (measles, mumps, rubella) vaccine requires multiple immunizations in the first year because it is composed of whole killed viruses.

Infection with the fungus Coccidioides immitis is commonly diagnosed using a(n) ________ assay.

Which of the following statements regarding an inactivated vaccine is FALSE?

Infection with HIV is routinely verified using a(n) ________ assay.

A woman uses a home pregnancy test kit that tests for hCG hormone in urine. She knows this is a type of antibody assay from the kit brochure. Antibodies reacting with the hormone produce two lines on the test strip. What specific type of antibody assay does this represent?

a person who has been exposed to rabies receives both HRIG (human rabies immunoglobulin) injected near the bite site and the rabies vaccine. What does this strategy represent?

Contact immunity within a population can be produced by ________ vaccines.

Infection with influenzavirus is commonly diagnosed using

The attenuated oral poliovirus vaccine (OVP) is no longer administered in the U.S.A. because it

The assay shown in Figure 17.1 is used for what?

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