Question 1

Contact dermatitis is a type (I/II/III/IV) hypersensitivity disorder.

Accepted Answer

IV

Question 2

Which of the following bind the constant region of IgE?

Accepted Answer

A)  eosinophils 
B)  mast cells 
C)  monocytes 
D)  both mast cells and monocytes 
E)  both eosinophils and mast cells 
A)  eosinophils 
B)  mast cells 
C)  monocytes 
D)  both mast cells and monocytes 
E)  both eosinophils and mast cells E

Question 3

Which of the following immunoglobulins is produced by plasma cells in response to an allergen?

Accepted Answer

A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM 
A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM C

Question 4

Many of the signs and symptoms of inflammation, including redness and itching, are due to the release of (histamines/leukotrienes/proteases) by degranulation of mast cells.

Accepted Answer

The answer of Many of the signs and symptoms of...

Question 5

A child has a history of recurring serious bacterial infections. A blood sample shows lymphocyte levels are a little below normal, and no antibodies to the pathogens are detected in serologic tests. Based on this information, which of the following is the likeliest diagnosis for this child?

Accepted Answer

A)  Bruton-type agammaglobulinemia 
B)  Grave's disease 
C)  severe combined immune deficiency (SCI
D)  
D)  systemic lupus erythematosus (SL
E)  
E)  hemolytic disease of the newborn 
A)  Bruton-type agammaglobulinemia 
B)  Grave's disease 
C)  severe combined immune deficiency (SCI
D)  
D)  systemic lupus erythematosus (SL
E)  
E)  hemolytic disease of the newborn

Question 6

Compare and contrast type I hypersensitivity with type IV hypersensitivity with respect to reaction time, mediators, and cells involved.

Accepted Answer

Type I (immediate) hypersensitivity is v

Question 7

The condition known as graft-versus-host disease may result after

Accepted Answer

A)  a bone marrow allograft. 
B)  a mismatched blood transfusion. 
C)  a bone allograft. 
D)  a plasmapheresis procedure. 
E)  any type of allograft procedure. 
A)  a bone marrow allograft. 
B)  a mismatched blood transfusion. 
C)  a bone allograft. 
D)  a plasmapheresis procedure. 
E)  any type of allograft procedure.

Question 8

An accident victim receives a blood transfusion. Shortly thereafter, he begins to have difficulty breathing, develops a fever, and experiences nausea and vomiting. Which of the following is the most likely interpretation of these events?

Accepted Answer

A)  the blood transfusion was mismatched. 
B)  the blood transfusion contained pyrogens. 
C)  the recipient had previously been exposed to foreign blood group antigens. 
D)  the blood transfusion was mismatched and contained pyrogens. 
E)  the blood transfusion was mismatched and the recipient had previously been exposed to the foreign blood group antigens. 
A)  the blood transfusion was mismatched. 
B)  the blood transfusion contained pyrogens. 
C)  the recipient had previously been exposed to foreign blood group antigens. 
D)  the blood transfusion was mismatched and contained pyrogens. 
E)  the blood transfusion was mismatched and the recipient had previously been exposed to the foreign blood group antigens.

Question 9

A patient arrives at a hospital suffering from serious difficulty breathing and shortness of breath. Initial tests indicate none of the standard respiratory infectious agents are present. The physician suspects an immune disorder. What clinical indicators would distinguish between asthma, pneumonitis and Pneumocystic pneumonia?

Accepted Answer

Asthma would produce high levels of hist

Question 10

When immune complexes in the blood become trapped in the kidneys the resulting disease is known as

Accepted Answer

A)  autoimmunity. 
B)  hemolytic disease. 
C)  glomerulonephritis. 
D)  urticaria. 
E)  anaphylaxis. 
A)  autoimmunity. 
B)  hemolytic disease. 
C)  glomerulonephritis. 
D)  urticaria. 
E)  anaphylaxis.

Question 11

The most common type of transplant involves an (allograft/autograft/isograft).

Accepted Answer

The answer of The most common type of transplant involves...

Question 12

Infection with certain viruses may lead to the development of type I diabetes.

Accepted Answer

A) True 
 B)False

Question 13

MHC genes are significant genetic factors in predisposition to develop autoimmune disease.

Accepted Answer

A) True 
 B)False

Question 14

A person identified as a universal recipient has ________ blood type.

Accepted Answer

A)  A 
B)  B 
C)  AB 
D)  O 
E)  Rh-negative 
A)  A 
B)  B 
C)  AB 
D)  O 
E)  Rh-negative

Question 15

The effectiveness of ART is determined by (ELISA/IFA/PCR) testing.

Accepted Answer

The answer of The effectiveness of ART is determined by...

Question 16

Opportunistic infections typical of AIDS but rare otherwise include

Accepted Answer

A)  tuberculosis. 
B)  Pneumocystis pneumonia. 
C)  Kaposi's sarcoma. 
D)  tuberculosis and shingles. 
E)  Pneumocystis pneumonia and Kaposi's sarcoma. 
A)  tuberculosis. 
B)  Pneumocystis pneumonia. 
C)  Kaposi's sarcoma. 
D)  tuberculosis and shingles. 
E)  Pneumocystis pneumonia and Kaposi's sarcoma.

Question 17

What is the function of the kinins released when mast cells degranulate?

Accepted Answer

A)  activation of the complement system 
B)  increased vascular permeability 
C)  smooth muscle contraction 
D)  increased production of tears and saliva 
E)  chemotactic factors 
A)  activation of the complement system 
B)  increased vascular permeability 
C)  smooth muscle contraction 
D)  increased production of tears and saliva 
E)  chemotactic factors

Question 18

Depletion of the helper T cell population by HIV results in the development of AIDS.

Accepted Answer

A) True 
 B)False

Question 19

Type I diabetes is a(n)

Accepted Answer

A)  autoimmune disease. 
B)  immunodeficiency disease. 
C)  immune complex-mediated hypersensitivity disorder. 
D)  delayed hypersensitivity disorder. 
E)  immediate hypersensitivity disorder. 
A)  autoimmune disease. 
B)  immunodeficiency disease. 
C)  immune complex-mediated hypersensitivity disorder. 
D)  delayed hypersensitivity disorder. 
E)  immediate hypersensitivity disorder.

Question 20

If an Rh-positive woman marries an Rh-negative man, their children are at risk for hemolytic disease of the newborn.

Accepted Answer

A) True 
 B)False

Exam 18: Immune Disorders

Contact dermatitis is a type (I/II/III/IV) hypersensitivity disorder.

Which of the following bind the constant region of IgE?

Which of the following immunoglobulins is produced by plasma cells in response to an allergen?

Many of the signs and symptoms of inflammation, including redness and itching, are due to the release of (histamines/leukotrienes/proteases) by degranulation of mast cells.

A child has a history of recurring serious bacterial infections. A blood sample shows lymphocyte levels are a little below normal, and no antibodies to the pathogens are detected in serologic tests. Based on this information, which of the following is the likeliest diagnosis for this child?

Compare and contrast type I hypersensitivity with type IV hypersensitivity with respect to reaction time, mediators, and cells involved.

The condition known as graft-versus-host disease may result after

An accident victim receives a blood transfusion. Shortly thereafter, he begins to have difficulty breathing, develops a fever, and experiences nausea and vomiting. Which of the following is the most likely interpretation of these events?

When immune complexes in the blood become trapped in the kidneys the resulting disease is known as

The most common type of transplant involves an (allograft/autograft/isograft).

Infection with certain viruses may lead to the development of type I diabetes.

MHC genes are significant genetic factors in predisposition to develop autoimmune disease.

A person identified as a universal recipient has ________ blood type.

The effectiveness of ART is determined by (ELISA/IFA/PCR) testing.

Opportunistic infections typical of AIDS but rare otherwise include

What is the function of the kinins released when mast cells degranulate?

Depletion of the helper T cell population by HIV results in the development of AIDS.

Type I diabetes is a(n)

If an Rh-positive woman marries an Rh-negative man, their children are at risk for hemolytic disease of the newborn.

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