Question 1

Jess has A- blood type, has never received a blood transfusion, and never been pregnant. Antibodies against what blood antigens could be present in Jess' blood?

Accepted Answer

A)  O and Rh antigens 
B)  B antigens 
C)  A antigens 
D)  B and Rh antigens 
E)  O antigens 
A)  O and Rh antigens 
B)  B antigens 
C)  A antigens 
D)  B and Rh antigens 
E)  O antigens

Question 2

Graves' disease is an autoimmune disease that affects the (lymph/thyroid/adrenal) gland.

Accepted Answer

The answer of Graves' disease is an autoimmune disease that...

Question 3

Which of the following statements concerning allografts is TRUE?

Accepted Answer

A)  They are the best type of transplants because they are not associated with rejection. 
B)  They induce strong type IV hypersensitivity reactions and must be treated with immunosuppressive drugs. 
C)  They always require complete destruction of the recipient's bone marrow cells. 
D)  They are impossible to perform because the antigens between donor and recipient are so different. 
E)  They are the rarest type of transplants. 
A)  They are the best type of transplants because they are not associated with rejection. 
B)  They induce strong type IV hypersensitivity reactions and must be treated with immunosuppressive drugs. 
C)  They always require complete destruction of the recipient's bone marrow cells. 
D)  They are impossible to perform because the antigens between donor and recipient are so different. 
E)  They are the rarest type of transplants.

Question 4

If a T cell is exposed to a "hidden" antigen, what kind of immune reaction will result?

Accepted Answer

A)  an autoimmune disease 
B)  a delayed hypersensitivity reaction 
C)  a cytotoxic hypersensitivity reaction 
D)  allergic contact dermatitis 
E)  an allergy 
A)  an autoimmune disease 
B)  a delayed hypersensitivity reaction 
C)  a cytotoxic hypersensitivity reaction 
D)  allergic contact dermatitis 
E)  an allergy

Question 5

Which of the following statements concerning rheumatoid arthritis (RA) is TRUE?

Accepted Answer

A)  It occurs in humans and animals. 
B)  The symptoms are due to damage caused by cytotoxic T cells. 
C)  There is no genetic influence on the likelihood of developing RA. 
D)  Accumulations of antibody complexes lead to inflammation in and destruction of the joints. 
E)  The onset of disease is clearly correlated with having been infected with a specific microbe. 
A)  It occurs in humans and animals. 
B)  The symptoms are due to damage caused by cytotoxic T cells. 
C)  There is no genetic influence on the likelihood of developing RA. 
D)  Accumulations of antibody complexes lead to inflammation in and destruction of the joints. 
E)  The onset of disease is clearly correlated with having been infected with a specific microbe.

Question 6

One of the important inherited defects in the second line of immune defense is a condition called chronic granulomatous disease. What is this disease, and how is it caused?

Accepted Answer

Chronic granulomatous disease is a type

Question 7

The syndrome known as AIDS is characterized

Accepted Answer

A)  by the presence of HIV. 
B)  as an opportunistic disease resulting from herpesvirus reactivation. 
C)  by CTL attack on CD4 T cells. 
D)  by one or more opportunistic diseases and the presence of HIV. 
E)  by the presence of anti-HIV antibodies. 
A)  by the presence of HIV. 
B)  as an opportunistic disease resulting from herpesvirus reactivation. 
C)  by CTL attack on CD4 T cells. 
D)  by one or more opportunistic diseases and the presence of HIV. 
E)  by the presence of anti-HIV antibodies.

Question 8

Graft rejection can be reduced by

Accepted Answer

A)  preventing B cell activation. 
B)  antiphagocytic factors. 
C)  antihistimines. 
D)  preventing T cell proliferation. 
E)  epinephrine. 
A)  preventing B cell activation. 
B)  antiphagocytic factors. 
C)  antihistimines. 
D)  preventing T cell proliferation. 
E)  epinephrine.

Question 9

Which of the following is an example of a type I hypersensitivity reaction?

Accepted Answer

A)  watery eyes after exposure to animals 
B)  destruction of red blood cells after an incompatible blood transfusion 
C)  farmer's lung 
D)  immune complexes accumulation in the kidneys 
E)  the tuberculin response 
A)  watery eyes after exposure to animals 
B)  destruction of red blood cells after an incompatible blood transfusion 
C)  farmer's lung 
D)  immune complexes accumulation in the kidneys 
E)  the tuberculin response

Question 10

Type I hypersensitivity reactions are also commonly known as (allergies/autoimmunities/inflammation).

Accepted Answer

The answer of Type I hypersensitivity reactions are also commonly...

Question 11

An agricultural worker experiences difficulty breathing which becomes progressively worse. Tests show inflammation and damage of the lung tissue, but IgE antibodies and granulocytes are in the normal ranges. With which disorder of the immune system are these signs and symptoms consistent?

Accepted Answer

A)  allergic reaction 
B)  type III (immune complex-mediated) hypersensitivity 
C)  type IV (delayed) hypersensitivity 
D)  autoimmunity 
E)  acquired immunodeficiency 
A)  allergic reaction 
B)  type III (immune complex-mediated) hypersensitivity 
C)  type IV (delayed) hypersensitivity 
D)  autoimmunity 
E)  acquired immunodeficiency

Question 12

What is the underlying problem in most acquired immunodeficiencies?

Accepted Answer

A)  declining cell-mediated immunity 
B)  declining humoral immunity 
C)  production of autoantibodies 
D)  eosinophilia 
E)  anemia 
A)  declining cell-mediated immunity 
B)  declining humoral immunity 
C)  production of autoantibodies 
D)  eosinophilia 
E)  anemia

Question 13

Chronic granulomatous disease is a disorder of the (first/second/third) line of immune defense.

Accepted Answer

The answer of Chronic granulomatous disease is a disorder of...

Question 14

Hypotheses explaining the development of autoimmune disease include

Accepted Answer

A)  molecular mimicry. 
B)  genetic factors. 
C)  overuse of vaccines. 
D)  molecular mimicry and vaccines. 
E)  molecular mimicry and genetic factors. 
A)  molecular mimicry. 
B)  genetic factors. 
C)  overuse of vaccines. 
D)  molecular mimicry and vaccines. 
E)  molecular mimicry and genetic factors.

Question 15

Antigen-antibody complexes trapped in tissues and triggering complement activation or mast cell degranulation are characteristic of

Accepted Answer

A)  type I hypersensitivity. 
B)  type II hypersensitivity. 
C)  type III hypersensitivity. 
D)  autoimmunity. 
E)  graft rejection. 
A)  type I hypersensitivity. 
B)  type II hypersensitivity. 
C)  type III hypersensitivity. 
D)  autoimmunity. 
E)  graft rejection.

Exam 18: Immune Disorders

Jess has A- blood type, has never received a blood transfusion, and never been pregnant. Antibodies against what blood antigens could be present in Jess' blood?

Graves' disease is an autoimmune disease that affects the (lymph/thyroid/adrenal) gland.

Which of the following statements concerning allografts is TRUE?

If a T cell is exposed to a "hidden" antigen, what kind of immune reaction will result?

Which of the following statements concerning rheumatoid arthritis (RA) is TRUE?

One of the important inherited defects in the second line of immune defense is a condition called chronic granulomatous disease. What is this disease, and how is it caused?

The syndrome known as AIDS is characterized

Graft rejection can be reduced by

Which of the following is an example of a type I hypersensitivity reaction?

Type I hypersensitivity reactions are also commonly known as (allergies/autoimmunities/inflammation).

An agricultural worker experiences difficulty breathing which becomes progressively worse. Tests show inflammation and damage of the lung tissue, but IgE antibodies and granulocytes are in the normal ranges. With which disorder of the immune system are these signs and symptoms consistent?

What is the underlying problem in most acquired immunodeficiencies?

Chronic granulomatous disease is a disorder of the (first/second/third) line of immune defense.

Hypotheses explaining the development of autoimmune disease include

Antigen-antibody complexes trapped in tissues and triggering complement activation or mast cell degranulation are characteristic of

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