Question 1

Describe the tuberculin response and identify the type of response involved.

Accepted Answer

The tuberculin response is a type of del

Question 2

Primary immunodeficiency diseases

Accepted Answer

A)  develop later in life. 
B)  are detectable close to birth. 
C)  may be caused by malnutrition. 
D)  are never associated with genetic defects. 
E)  are sometimes caused by severe stress. 
A)  develop later in life. 
B)  are detectable close to birth. 
C)  may be caused by malnutrition. 
D)  are never associated with genetic defects. 
E)  are sometimes caused by severe stress.

Question 3

All autoimmune diseases have a genetic cause.

Accepted Answer

A) True 
 B)False

Question 4

Multiple sclerosis is

Accepted Answer

A)  a type IV hypersensitivity disease in which cytotoxic T cells attack the myelin sheath of neurons. 
B)  a genetic birth defect of the nervous system. 
C)  a type II hypersensitivity to the myelin of neurons. 
D)  the formation of antibodies against transplanted tissue. 
E)  a neurological disease due to the accumulation of immune complexes in nerves. 
A)  a type IV hypersensitivity disease in which cytotoxic T cells attack the myelin sheath of neurons. 
B)  a genetic birth defect of the nervous system. 
C)  a type II hypersensitivity to the myelin of neurons. 
D)  the formation of antibodies against transplanted tissue. 
E)  a neurological disease due to the accumulation of immune complexes in nerves.

Question 5

The HIV virion attaches to ________ on the surface of lymphocytes.

Accepted Answer

A)  IgG 
B)  MHC II 
C)  IL-2R 
D)  CD4 
E)  CD3 
A)  IgG 
B)  MHC II 
C)  IL-2R 
D)  CD4 
E)  CD3

Question 6

Binding of IgE to the surface of sensitized cells leads to (activation/degranulation/lysis) of the cell, releasing many inflammatory chemicals.

Accepted Answer

The answer of Binding of IgE to the surface of...

Question 7

When mast cells degranulate and release histamine, which of the following events may occur?

Accepted Answer

A)  constriction of small blood vessels 
B)  bronchial spasms 
C)  increased mucus production 
D)  both constriction of small blood vessels and bronchial spasms 
E)  both bronchial spasms and increased mucus production 
A)  constriction of small blood vessels 
B)  bronchial spasms 
C)  increased mucus production 
D)  both constriction of small blood vessels and bronchial spasms 
E)  both bronchial spasms and increased mucus production

Question 8

In the wake of the recent Ebola outbreak in West Africa, researchers have observed infectious Ebola virus is present in the eyes and semen of infected individuals months after apparent recovery from the acute stage of the disease. Based on information in this chapter, propose an explanation for this observation.

Accepted Answer

The eyes and testes are "hidden" sites w

Question 9

A reaction to an allergen is a ________ hypersensitivity.

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  type V 
A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  type V

Question 10

Rheumatoid arthritis is a type (I/II/III/IV) hypersensitivity reaction that results when B cells produce autoantibodies that damage the joints.

Accepted Answer

The answer of Rheumatoid arthritis is a type (I/II/III/IV) hypersensitivity...

Question 11

Which of the following types of cells is NOT infected by HIV?

Accepted Answer

A)  T cells 
B)  B cells 
C)  macrophages 
D)  monocytes 
E)  microglia 
A)  T cells 
B)  B cells 
C)  macrophages 
D)  monocytes 
E)  microglia

Question 12

Immunological attack on the islets of Langerhans resulting in the inability to produce insulin leads to type (I/II/IV) diabetes Mellitus.

Accepted Answer

The answer of Immunological attack on the islets of Langerhans...

Question 13

A small amount of antigen is injected under the skin of a patient. After 30 minutes there is no apparent change at the injection site, but 36 hours later the patient reports that the area is red and swollen. This type of response is due to

Accepted Answer

A)  type I hypersensitivity. 
B)  type II hypersensitivity. 
C)  type III hypersensitivity. 
D)  type IV hypersensitivity. 
E)  immunodeficiency. 
A)  type I hypersensitivity. 
B)  type II hypersensitivity. 
C)  type III hypersensitivity. 
D)  type IV hypersensitivity. 
E)  immunodeficiency.

Question 14

The release of ________ during a type I hypersensitivity reaction contributes to swelling.

Accepted Answer

A)  histamine 
B)  prostaglandins 
C)  leukotrienes 
D)  both histamines and leukotrienes 
E)  both proteases and prostaglandins 
A)  histamine 
B)  prostaglandins 
C)  leukotrienes 
D)  both histamines and leukotrienes 
E)  both proteases and prostaglandins

Question 15

What is the cause of hemolytic disease of the newborn?

Accepted Answer

A)  The mother has eosinophilia during pregnancy. 
B)  An O blood type mother produces anti-A antibodies which cross the placenta and react with the baby's A antigens. 
C)  Antibodies of an A or B blood type mother cross the placenta and react with baby's O antigens. 
D)  The mother produces anti-Rh antibodies which cross the placenta and react with baby's Rh antigens. 
E)  The mother's mast cells degranulate in the placenta, damaging it. 
A)  The mother has eosinophilia during pregnancy. 
B)  An O blood type mother produces anti-A antibodies which cross the placenta and react with the baby's A antigens. 
C)  Antibodies of an A or B blood type mother cross the placenta and react with baby's O antigens. 
D)  The mother produces anti-Rh antibodies which cross the placenta and react with baby's Rh antigens. 
E)  The mother's mast cells degranulate in the placenta, damaging it.

Question 16

The mechanism of action of RhoGAM is to (activate/neutralize/prevent) an anti-Rh immune response.

Accepted Answer

The answer of The mechanism of action of RhoGAM is...

Question 17

The responses observed in type IV hypersensitivities result from the action of

Accepted Answer

A)  IgE antibodies and mast cells. 
B)  T cells and phagocytes. 
C)  IgG and complement. 
D)  autoantibodies. 
E)  inflammatory chemicals. 
A)  IgE antibodies and mast cells. 
B)  T cells and phagocytes. 
C)  IgG and complement. 
D)  autoantibodies. 
E)  inflammatory chemicals.

Question 18

Antibody binding to receptors on the thyroid may result in

Accepted Answer

A)  multiple sclerosis. 
B)  Graves' disease. 
C)  DiGeorge syndrome. 
D)  type I diabetes. 
E)  autoimmune hemolytic anemia. 
A)  multiple sclerosis. 
B)  Graves' disease. 
C)  DiGeorge syndrome. 
D)  type I diabetes. 
E)  autoimmune hemolytic anemia.

Question 19

Systemic lupus erythematosus (SLE or lupus) is distinct from other autoimmune disorders because

Accepted Answer

A)  it is also a hypersensitivity disorder. 
B)  it involves an antibody response. 
C)  multiple organs and tissues are affected. 
D)  it may be triggered by an infection. 
E)  there is a genetic predisposition. 
A)  it is also a hypersensitivity disorder. 
B)  it involves an antibody response. 
C)  multiple organs and tissues are affected. 
D)  it may be triggered by an infection. 
E)  there is a genetic predisposition.

Question 20

Which of the following is a type of blood cell that undergoes degranulation in type I hypersensitivity reactions?

Accepted Answer

A)  B cell 
B)  basophil 
C)  T cell 
D)  macrophage 
E)  plasma cell 
A)  B cell 
B)  basophil 
C)  T cell 
D)  macrophage 
E)  plasma cell

Exam 18: Immune Disorders

Describe the tuberculin response and identify the type of response involved.

Primary immunodeficiency diseases

All autoimmune diseases have a genetic cause.

Multiple sclerosis is

The HIV virion attaches to ________ on the surface of lymphocytes.

Binding of IgE to the surface of sensitized cells leads to (activation/degranulation/lysis) of the cell, releasing many inflammatory chemicals.

When mast cells degranulate and release histamine, which of the following events may occur?

A reaction to an allergen is a ________ hypersensitivity.

Rheumatoid arthritis is a type (I/II/III/IV) hypersensitivity reaction that results when B cells produce autoantibodies that damage the joints.

Which of the following types of cells is NOT infected by HIV?

Immunological attack on the islets of Langerhans resulting in the inability to produce insulin leads to type (I/II/IV) diabetes Mellitus.

A small amount of antigen is injected under the skin of a patient. After 30 minutes there is no apparent change at the injection site, but 36 hours later the patient reports that the area is red and swollen. This type of response is due to

The release of ________ during a type I hypersensitivity reaction contributes to swelling.

What is the cause of hemolytic disease of the newborn?

The mechanism of action of RhoGAM is to (activate/neutralize/prevent) an anti-Rh immune response.

The responses observed in type IV hypersensitivities result from the action of

Antibody binding to receptors on the thyroid may result in

Systemic lupus erythematosus (SLE or lupus) is distinct from other autoimmune disorders because

Which of the following is a type of blood cell that undergoes degranulation in type I hypersensitivity reactions?

A Brief History of Microbiology

The Chemistry of Microbiology

Cell Structure and Function

Microscopy, Staining, and Classification

Microbial Metabolism

Microbial Nutrition and Growth

Microbial Genetics

Recombinant DNA Technology

Controlling Microbial Growth in the Environment

Controlling Microbial Growth in the Body: Antimicrobial Drugs

Characterizing and Classifying Prokaryotes

Characterizing and Classifying Eukaryotes

Characterizing and Classifying Viruses, Viroids, and Prions

Infection, Infectious Diseases, and Epidemiology

Innate Immunity

Adaptive Immunity

Immunization and Immune Testing

Microbial Diseases of the Skin and Wounds

Microbial Diseases of the Nervous System and Eyes

Microbial Cardiovascular and Systemic Diseases

Microbial Diseases of the Respiratory System

Microbial Diseases of the Digestive System

Microbial Diseases of the Urinary and Reproductive Systems

Applied and Industrial Microbiology

Microbial Ecology and Microbiomes

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