Question 1

In what way does an uncompetitive inhibitor bind to an enzyme?

Accepted Answer

A)  It reversibly binds to the enzyme active site. 
B)  It irreversibly binds to the enzyme active site. 
C)  It reversibly binds to the enzyme-substrate complex but does not bind to the free enzyme. 
D)  It reversibly binds to both the free enzyme and the enzyme-substrate complex. 
E)  It irreversibly binds to an enzyme allosteric site. 
A)  It reversibly binds to the enzyme active site. 
B)  It irreversibly binds to the enzyme active site. 
C)  It reversibly binds to the enzyme-substrate complex but does not bind to the free enzyme. 
D)  It reversibly binds to both the free enzyme and the enzyme-substrate complex. 
E)  It irreversibly binds to an enzyme allosteric site.

Question 2

Which type of enzyme is responsible for attaching phosphate groups to specific amino acids?

Accepted Answer

A)  a protein phosphatase 
B)  a ribosylase 
C)  a protein kinase 
D)  a protein glycosylase 
E)  an ATPase 
A)  a protein phosphatase 
B)  a ribosylase 
C)  a protein kinase 
D)  a protein glycosylase 
E)  an ATPase

Question 3

Describe how glucagon and insulin regulate the enzymes involved in activating and deactivating glycogen phosphorylation, thus leading to or inhibiting energy-yielding carbohydrate metabolism in muscles.

Accepted Answer

Glucagon and insulin play crucial roles

Question 4

An enzyme catalyzes the reaction A $\rightarrow$B. The initial rate of the reaction was measured as a function of the concentration of A. The following data were obtained:
[A], micromolar
V0, nmoles/min
0.05
0.08
0.1
0.16
0.5
0.79
1
1.6
5
7.3
10
13
50
40
100
53
500
73
1,000
76
5,000
79
10,000
80
20,000
80
a) What is the Km of the enzyme for the substrate A?
b) What is the value of V0 when [A] = 43?
The above data were plotted as 1/V0 versus 1/[A], and a straight line was obtained.
c) What is the value of the y-intercept of the line?
d) What is the value of the x-intercept of the line?

Accepted Answer

To answer the questions provided, we nee

Question 5

An enzyme that can convert glucose into fructose is a member of which class of enzymes?

Accepted Answer

A)  oxidoreductases 
B)  transferases 
C)  hydrolases 
D)  lyases 
E)  isomerases 
A)  oxidoreductases 
B)  transferases 
C)  hydrolases 
D)  lyases 
E)  isomerases

Question 6

A reaction that has a $\Delta$ G'° of 25 kJ/mol is likely to have which property?

Accepted Answer

A)  a large equilibrium constant 
B)  a small equilibrium constant 
C)  a slow reaction rate 
D)  both a large equilibrium constant and a slow reaction rate 
E)  both a small equilibrium constant and a slow reaction rate 
A)  a large equilibrium constant 
B)  a small equilibrium constant 
C)  a slow reaction rate 
D)  both a large equilibrium constant and a slow reaction rate 
E)  both a small equilibrium constant and a slow reaction rate

In what way does an uncompetitive inhibitor bind to an enzyme?

Which type of enzyme is responsible for attaching phosphate groups to specific amino acids?

Describe how glucagon and insulin regulate the enzymes involved in activating and deactivating glycogen phosphorylation, thus leading to or inhibiting energy-yielding carbohydrate metabolism in muscles.

An enzyme that can convert glucose into fructose is a member of which class of enzymes?

A reaction that has a $\Delta$ G'° of 25 kJ/mol is likely to have which property?

The Foundations of Biochemistry

Water

Amino Acids, Peptides, and Proteins

The Three-Dimensional Structure of Proteins

Protein Function

Carbohydrates and Glycobiology

Nucleotides and Nucleic Acids

DNA-Based Information Technologies

Lipids

Biological Membranes and Transport

Biosignaling

Bioenergetics and Biochemical Reaction Types

Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway

Principles of Metabolic Regulation

The Citric Acid Cycle

Fatty Acid Catabolism

Amino Acid Oxidation and the Production of Urea

Oxidative Phosphorylation and Photophosphorylation

Carbohydrate Biosynthesis in Plants and Bacteria

Lipid Biosynthesis

Biosynthesis of Amino Acids, Nucleotides, and Related Molecules

Hormonal Regulation and Integration of Mammalian Metabolism

Genes and Chromosomes

DNA Metabolism

RNA Metabolism

Protein Metabolism

Regulation of Gene Expression

Filters

Exam 6: Enzymes

In what way does an uncompetitive inhibitor bind to an enzyme?

Which type of enzyme is responsible for attaching phosphate groups to specific amino acids?

Describe how glucagon and insulin regulate the enzymes involved in activating and deactivating glycogen phosphorylation, thus leading to or inhibiting energy-yielding carbohydrate metabolism in muscles.

An enzyme that can convert glucose into fructose is a member of which class of enzymes?

A reaction that has a Δ\DeltaΔ G'° of 25 kJ/mol is likely to have which property?

The Foundations of Biochemistry

Water

Amino Acids, Peptides, and Proteins

The Three-Dimensional Structure of Proteins

Protein Function

Carbohydrates and Glycobiology

Nucleotides and Nucleic Acids

DNA-Based Information Technologies

Lipids

Biological Membranes and Transport

Biosignaling

Bioenergetics and Biochemical Reaction Types

Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway

Principles of Metabolic Regulation

The Citric Acid Cycle

Fatty Acid Catabolism

Amino Acid Oxidation and the Production of Urea

Oxidative Phosphorylation and Photophosphorylation

Carbohydrate Biosynthesis in Plants and Bacteria

Lipid Biosynthesis

Biosynthesis of Amino Acids, Nucleotides, and Related Molecules

Hormonal Regulation and Integration of Mammalian Metabolism

Genes and Chromosomes

DNA Metabolism

RNA Metabolism

Protein Metabolism

Regulation of Gene Expression

Filters

A reaction that has a $\Delta$ G'° of 25 kJ/mol is likely to have which property?