Question 1

An unusual structural feature of the lac repressor is that it is a

Accepted Answer

A)  homodimer. 
B)  homotetramer. 
C)  heterodimer. 
D)  heterotetramer. 
A)  homodimer. 
B)  homotetramer. 
C)  heterodimer. 
D)  heterotetramer.

Question 2

When DNA is damaged,what protein is activated?

Accepted Answer

A)  LexA repressor 
B)  RecA 
C)  SOS operon 
D)  lac operon 
A)  LexA repressor 
B)  RecA 
C)  SOS operon 
D)  lac operon

Question 3

When bacteriophage   integrates into the E.coli genome,what is that lifestyle called?

Accepted Answer

A)  lysis 
B)  lysogeny 
C)  lyophilize 
D)  lysine 
A)  lysis 
B)  lysogeny 
C)  lyophilize 
D)  lysine

Question 4

The best description of how allosteric regulation works is that a ligand __________ the transcriptional regulatory protein,which __________ the protein's affinity for DNA.

Accepted Answer

A)  covalently modifies; increases 
B)  covalently modifies; decreases 
C)  binds to; causes conformational changes that affect 
D)  binds to; causes conformational changes that can only decrease 
A)  covalently modifies; increases 
B)  covalently modifies; decreases 
C)  binds to; causes conformational changes that affect 
D)  binds to; causes conformational changes that can only decrease

Question 5

A regulon can best be described as units of DNA containing __________ gene(s)under control of __________ promotor(s).

Accepted Answer

A)  one; one 
B)  multiple; one 
C)  multiple; multiple 
D)  one; multiple 
A)  one; one 
B)  multiple; one 
C)  multiple; multiple 
D)  one; multiple

Question 6

Which amino acid residues on histones are acetylated?

Accepted Answer

A)  histidine 
B)  lysine 
C)  arginine 
D)  serine 
A)  histidine 
B)  lysine 
C)  arginine 
D)  serine

Question 7

The function of an insulator sequence in DNA is to

Accepted Answer

A)  amplify the action of enhancers. 
B)  counteract the action of enhancers. 
C)  inhibit promoters. 
D)  activate RNA synthesis. 
A)  amplify the action of enhancers. 
B)  counteract the action of enhancers. 
C)  inhibit promoters. 
D)  activate RNA synthesis.

Question 8

iPS cells can be defined as __________ cells.

Accepted Answer

A)  differentiated 
B)  dedifferentiated 
C)  embryonic stem 
D)  somatic stem 
A)  differentiated 
B)  dedifferentiated 
C)  embryonic stem 
D)  somatic stem

Question 9

A protein that has a weak affinity for a DNA site and is at ___________ concentrations of protein will bind to DNA __________.

Accepted Answer

A)  low; strongly 
B)  high; strongly 
C)  low; indiscriminately 
D)  high; indiscriminately 
A)  low; strongly 
B)  high; strongly 
C)  low; indiscriminately 
D)  high; indiscriminately

Question 10

When there is no lactose in a cell,production of lac operon

Accepted Answer

A)  increases. 
B)  decreases. 
C)  turns off completely. 
D)  production of lac operon does not depend on lactose concentration. 
A)  increases. 
B)  decreases. 
C)  turns off completely. 
D)  production of lac operon does not depend on lactose concentration.

Question 11

Compare the two mechanisms used for control of the trp operon.

Accepted Answer

The first mechanism is by the action of

Question 12

Describe the two primary functions of transcriptional activator proteins.

Accepted Answer

(1)Recruit chromatin modifiers

Question 13

Predict the state of yeast when GAL 80 is bound to GAL 4 activation domain.

Accepted Answer

A)  high glucose concentration 
B)  low glucose concentration 
C)  high galactose concentration 
D)  low galactose concentration 
A)  high glucose concentration 
B)  low glucose concentration 
C)  high galactose concentration 
D)  low galactose concentration

Question 14

By wrapping DNA around the histone octamer,how much smaller can DNA be?

Accepted Answer

A)  tenfold 
B)  eightfold 
C)  sevenfold 
D)  twofold 
A)  tenfold 
B)  eightfold 
C)  sevenfold 
D)  twofold

Question 15

What kind of control mechanism is ligand-induced binding of an activator protein?

Accepted Answer

A)  positive 
B)  negative 
C)  neutral 
D)  covalent 
A)  positive 
B)  negative 
C)  neutral 
D)  covalent

Question 16

The function of the lac operon is to provide

Accepted Answer

A)  the enzymes needed to utilize the disaccharide lactose. 
B)  the enzymes needed to produce lactose. 
C)  lactose. 
D)  glucose and galactose to make lactose. 
A)  the enzymes needed to utilize the disaccharide lactose. 
B)  the enzymes needed to produce lactose. 
C)  lactose. 
D)  glucose and galactose to make lactose.

Question 17

When Cro is bound to OR3,the

Accepted Answer

A)  lysogenic pathway is favored. 
B)  lytic pathway is favored. 
C)  Cro protein inhibits the PR promoter. 
D)  CI protein activates the PRM promoter. 
A)  lysogenic pathway is favored. 
B)  lytic pathway is favored. 
C)  Cro protein inhibits the PR promoter. 
D)  CI protein activates the PRM promoter.

Question 18

When IPTG is added to a cell,what is the predicted outcome?

Accepted Answer

A)  Protein synthesis stops. 
B)  Protein overproduction occurs. 
C)  The DNA sequence coding for a given protein is altered. 
D)  An epigenetic state occurs. 
A)  Protein synthesis stops. 
B)  Protein overproduction occurs. 
C)  The DNA sequence coding for a given protein is altered. 
D)  An epigenetic state occurs.

Question 19

One of the most common binding interactions between proteins and DNA are __________ bonds.

Accepted Answer

A)  ionic 
B)  covalent 
C)  hydrogen 
D)  polar 
A)  ionic 
B)  covalent 
C)  hydrogen 
D)  polar

Exam 23: Gene Regulation

An unusual structural feature of the lac repressor is that it is a

When DNA is damaged,what protein is activated?

When bacteriophage integrates into the E.coli genome,what is that lifestyle called?

The best description of how allosteric regulation works is that a ligand __________ the transcriptional regulatory protein,which __________ the protein's affinity for DNA.

A regulon can best be described as units of DNA containing __________ gene(s)under control of __________ promotor(s).

Which amino acid residues on histones are acetylated?

The function of an insulator sequence in DNA is to

iPS cells can be defined as __________ cells.

A protein that has a weak affinity for a DNA site and is at ___________ concentrations of protein will bind to DNA __________.

When there is no lactose in a cell,production of lac operon

Compare the two mechanisms used for control of the trp operon.

Describe the two primary functions of transcriptional activator proteins.

Predict the state of yeast when GAL 80 is bound to GAL 4 activation domain.

By wrapping DNA around the histone octamer,how much smaller can DNA be?

What kind of control mechanism is ligand-induced binding of an activator protein?

The function of the lac operon is to provide

When Cro is bound to OR3,the

When IPTG is added to a cell,what is the predicted outcome?

One of the most common binding interactions between proteins and DNA are __________ bonds.

Principles of Biochemistry

Physical Biochemistry: Energy Conversion,water,and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Oxidative Phosphorylation

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Metabolic Integration

Dna Replication, repair, and Recombination

Rna Synthesis, processing, and Gene Silencing

Protein Synthesis, posttranslational Modification, and Transport

Filters

The best description of how allosteric regulation works is that a ligand the transcriptional regulatory protein,which the protein's affinity for DNA.

A regulon can best be described as units of DNA containing gene(s)under control of promotor(s).

A protein that has a weak affinity for a DNA site and is at _ concentrations of protein will bind to DNA .

When Cro is bound to O_R3,the