Question 1

In a leucine zipper,the leucine resides are found every seventh amino residue.This forces the supersecondary structure to be a(n)

Accepted Answer

A)    -helix. 
B)    -sheet. 
C)  coiled-coil. 
D)  hairpin turn. 
A)    -helix. 
B)    -sheet. 
C)  coiled-coil. 
D)  hairpin turn.

Question 2

The function of CRP in lac operon expression is to __________ the promoter by causing RNA polymerase to __________.

Accepted Answer

A)  stimulate; dissociate 
B)  stimulate; bind tighter 
C)  inhibit; dissociate 
D)  inhibit; bind tighter 
A)  stimulate; dissociate 
B)  stimulate; bind tighter 
C)  inhibit; dissociate 
D)  inhibit; bind tighter

Question 3

What are the two main approaches being considered for treatment using iPS cell technology?

Accepted Answer

The first approach is to reintroduce cel

Question 4

Compare and contrast the structures of the lac repressor protein and CRP.

Accepted Answer

The lac repressor is

Question 5

Using the figure below,explain how cooperativity works.

Accepted Answer

Weak interactions between the three comp

Question 6

Draw the four combinations of nucleotides and label the major groove in each as either an H-bond donor,an H-bond acceptor,or hydrophobic.

Accepted Answer

As shown in Figure 23.4,the A-T base pai

Question 7

What is a result of histone acetylation?

Accepted Answer

A)  repression of transcription 
B)  increased transcriptional activity 
C)  no effect 
D)  remodeling of histone 
A)  repression of transcription 
B)  increased transcriptional activity 
C)  no effect 
D)  remodeling of histone

Question 8

When LexA is autocleaved by RecA*,the SOS genes

Accepted Answer

A)  are repressed. 
B)  are activated. 
C)  are unaffected. 
D)  produce operons. 
A)  are repressed. 
B)  are activated. 
C)  are unaffected. 
D)  produce operons.

Question 9

When bacteriophage   generates progeny viruses that kill the bacterial host E.coli genome,what is that lifestyle called?

Accepted Answer

A)  lytic 
B)  lysogeny 
C)  lyophilize 
D)  lysine 
A)  lytic 
B)  lysogeny 
C)  lyophilize 
D)  lysine

Question 10

The function of RecA* is to

Accepted Answer

A)  inhibit expression of its own gene. 
B)  repress SOS genes. 
C)  stimulate LexA autocleavage. 
D)  allow LexA to accumulate. 
A)  inhibit expression of its own gene. 
B)  repress SOS genes. 
C)  stimulate LexA autocleavage. 
D)  allow LexA to accumulate.

Question 11

High concentration of CI protein in the cell __________ expression of the __________.

Accepted Answer

A)  prevents; lytic promoter 
B)  allows; lytic promoter 
C)  prevents; trp operon 
D)  allows; attenuator sequence 
A)  prevents; lytic promoter 
B)  allows; lytic promoter 
C)  prevents; trp operon 
D)  allows; attenuator sequence

Question 12

When there is a large presence of tryptophan,what effect that does that have on the Trp repressor?

Accepted Answer

A)  Trp repressor is bound. 
B)  Trp repressor is not bound. 
C)  There is initiation of RNA polymerase. 
D)  Transcriptional elongation by RNA polymerase is enhanced. 
A)  Trp repressor is bound. 
B)  Trp repressor is not bound. 
C)  There is initiation of RNA polymerase. 
D)  Transcriptional elongation by RNA polymerase is enhanced.

Question 13

Describe the transcriptional regulation of the GAL1 and GAL10 genes in yeast.

Accepted Answer

The GAL4 protein binds to the UASG.In th

Question 14

Allolactose acts as a(n)

Accepted Answer

A)  repressor by causing the lac repressor to bind. 
B)  inducer by binding to the lac repressor and causing it to dissociate. 
C)  repressor by increasing the binding affinity of the lac repressor. 
D)  inducer by binding to CRP. 
A)  repressor by causing the lac repressor to bind. 
B)  inducer by binding to the lac repressor and causing it to dissociate. 
C)  repressor by increasing the binding affinity of the lac repressor. 
D)  inducer by binding to CRP.

Question 15

Name the key elements of the lac operon.

Accepted Answer

The regulatory region and the structural

Question 16

Producing an iPS cell is remarkable because the pathway

Accepted Answer

A)  for conversion is general, not specific. 
B)  is a highly irreversible reaction. 
C)  for conversion is very specific and limited. 
D)  produces a very unstable cell. 
A)  for conversion is general, not specific. 
B)  is a highly irreversible reaction. 
C)  for conversion is very specific and limited. 
D)  produces a very unstable cell.

Question 17

Which of the following best describes how trans- and cis-acting factors operate?

Accepted Answer

A)  Cis-acting factors can bind to specific DNA sequences whereas trans-acting sites are DNA sequences. 
B)  Trans-acting factors can bind to specific DNA sequences whereas cis-acting sites are DNA sequences. 
C)  Trans- and cis-acting factors can both bind to specific DNA sequences. 
D)  Trans- and cis-acting factors can both only bind to DNA elements to which they are physically linked. 
A)  Cis-acting factors can bind to specific DNA sequences whereas trans-acting sites are DNA sequences. 
B)  Trans-acting factors can bind to specific DNA sequences whereas cis-acting sites are DNA sequences. 
C)  Trans- and cis-acting factors can both bind to specific DNA sequences. 
D)  Trans- and cis-acting factors can both only bind to DNA elements to which they are physically linked.

Question 18

Lysine methylation has what effect on the histone?

Accepted Answer

A)  leaves a positive charge on the amino acid 
B)  leaves a neutral charge on the amino acid 
C)  binds more strongly to the histone 
D)  removes chromatin docking sites 
A)  leaves a positive charge on the amino acid 
B)  leaves a neutral charge on the amino acid 
C)  binds more strongly to the histone 
D)  removes chromatin docking sites

Question 19

Differentiate between where bromodomains and chromodomains bind.

Accepted Answer

Bromodomain-containing complex

Question 20

Once RecA is no longer activated,what happens to the SOS regulon?

Accepted Answer

A)  LexA builds up and represses the SOS regulon. 
B)  LexA autocleaves and SOS regulon is activated. 
C)  LexA binds to the RecA. 
D)  LexA binds to the SOS regulon. 
A)  LexA builds up and represses the SOS regulon. 
B)  LexA autocleaves and SOS regulon is activated. 
C)  LexA binds to the RecA. 
D)  LexA binds to the SOS regulon.

Exam 23: Gene Regulation

In a leucine zipper,the leucine resides are found every seventh amino residue.This forces the supersecondary structure to be a(n)

The function of CRP in lac operon expression is to __________ the promoter by causing RNA polymerase to __________.

What are the two main approaches being considered for treatment using iPS cell technology?

Compare and contrast the structures of the lac repressor protein and CRP.

Using the figure below,explain how cooperativity works.

Draw the four combinations of nucleotides and label the major groove in each as either an H-bond donor,an H-bond acceptor,or hydrophobic.

What is a result of histone acetylation?

When LexA is autocleaved by RecA*,the SOS genes

When bacteriophage generates progeny viruses that kill the bacterial host E.coli genome,what is that lifestyle called?

The function of RecA* is to

High concentration of CI protein in the cell __________ expression of the __________.

When there is a large presence of tryptophan,what effect that does that have on the Trp repressor?

Describe the transcriptional regulation of the GAL1 and GAL10 genes in yeast.

Allolactose acts as a(n)

Name the key elements of the lac operon.

Producing an iPS cell is remarkable because the pathway

Which of the following best describes how trans- and cis-acting factors operate?

Lysine methylation has what effect on the histone?

Differentiate between where bromodomains and chromodomains bind.

Once RecA is no longer activated,what happens to the SOS regulon?

Principles of Biochemistry

Physical Biochemistry: Energy Conversion,water,and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Oxidative Phosphorylation

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Metabolic Integration

Dna Replication, repair, and Recombination

Rna Synthesis, processing, and Gene Silencing

Protein Synthesis, posttranslational Modification, and Transport

Filters

The function of CRP in lac operon expression is to the promoter by causing RNA polymerase to .

High concentration of CI protein in the cell expression of the .