Question 1

PPARs have a variety of functions in lipid metabolism that include all EXCEPT

Accepted Answer

A)  regulation of lipid transport. 
B)  mobilization of fatty acid oxidation. 
C)  mobilization of lipid synthesis. 
D)  decreasing insulin sensitivity. 
A)  regulation of lipid transport. 
B)  mobilization of fatty acid oxidation. 
C)  mobilization of lipid synthesis. 
D)  decreasing insulin sensitivity.

Question 2

Anorexigenic neurons express the __________ receptor.

Accepted Answer

A)  MC4 
B)  Y1/Y5 
C)  Y2 
D)  NPY 
A)  MC4 
B)  Y1/Y5 
C)  Y2 
D)  NPY

Question 3

Are thiazolidinediones agonists or antagonists of PPAR   
?

Accepted Answer

The answer of Are thiazolidinediones agonists or antagonists of PPAR...

Question 4

What is the fuel source for ATP production that is used in a 200-meter sprint?

Accepted Answer

A)  muscle phosphocreatine 
B)  liver glycogen 
C)  muscle glycogen 
D)  adipose tissue fatty acids 
A)  muscle phosphocreatine 
B)  liver glycogen 
C)  muscle glycogen 
D)  adipose tissue fatty acids

Question 5

Fad diets may lead to biochemical outcomes that are unfavorable.Which diet may lead to ketoacidosis?

Accepted Answer

A)  Atkins diet 
B)  Ornish diet 
C)  Weight Watchers 
D)  olestra-rich diet 
A)  Atkins diet 
B)  Ornish diet 
C)  Weight Watchers 
D)  olestra-rich diet

Question 6

How can hormone(s)cause the upregulation of the glucose transporter type 4 protein in liver and adipose cells?

Accepted Answer

Pancreatic beta  @#IMG-DLM&_TB6697_11cells secrete

Question 7

Differentiate the roles of the two different phosphorylation sites of insulin receptor substrate 1 (IRS1).Include the specific amino acids that are phosphorylated as well as the signaling pathway involved in your answer.

Accepted Answer

Phosphorylation of tyrosine (Tyr)results

Question 8

A patient has been diagnosed with metabolic syndrome.To establish the diagnosis,the doctor likely performed several tests.A test that the doctor was UNLIKELY to perform would be

Accepted Answer

A)  an assessment of abdominal obesity. 
B)  fasting followed by glucose tolerance test to establish insulin sensitivity. 
C)  monitoring of blood pressure. 
D)  a blood test for lipid levels. 
A)  an assessment of abdominal obesity. 
B)  fasting followed by glucose tolerance test to establish insulin sensitivity. 
C)  monitoring of blood pressure. 
D)  a blood test for lipid levels.

Question 9

Membrane fractions of skeletal muscle and adipose tissue were purified.Before purification the samples were exposed to insulin or glucagon.The samples were then analyzed via Western blotting using antibodies against GLUT4 and GLUT2.A loading control was included in the analysis.The results are shown below.Assume that sample A is skeletal muscle.Which sample corresponds to skeletal muscle that has been exposed to insulin? Explain your choice.

Accepted Answer

Samples C or D could be skelet

Question 10

If the bottom curve in this experiment represents the results from a normal human,the top curve represent the results from a human with what disease?

Accepted Answer

The answer of If the bottom curve in this experiment...

Question 11

A lack of energy balance may lead to

Accepted Answer

A)  type 1 diabetes. 
B)  a BMI value of less than 30, indicating obesity. 
C)  type 2 diabetes. 
D)  increased skeletal muscle breakdown. 
A)  type 1 diabetes. 
B)  a BMI value of less than 30, indicating obesity. 
C)  type 2 diabetes. 
D)  increased skeletal muscle breakdown.

Question 12

Which of the following is unlikely to affect metabolic homeostasis?

Accepted Answer

A)  physical activity 
B)  tissue dysfunction 
C)  psychological stress 
D)  telomere duplication 
A)  physical activity 
B)  tissue dysfunction 
C)  psychological stress 
D)  telomere duplication

Question 13

What is the physiological importance of PPAR   
signaling in liver cells after overnight fasting?

Accepted Answer

PPAR @#IMG-DLM&_TB6697_11 signaling after overnigh

Question 14

When calories consumed/day is equal to the calories expended/day,a person is considered to have a(n)__________.Describe the role of leptin in this process.

Accepted Answer

Energy balance.Leptin synthesis in visce

Question 15

Which of the following changes in metabolic flux would be expected to occur during long periods without food?

Accepted Answer

A)  decreased release of fatty acids from adipose tissue 
B)  decreased gluconeogenesis in liver and kidney cells 
C)  decreased ketogenesis in liver cells 
D)  protein degradation in skeletal muscle 
A)  decreased release of fatty acids from adipose tissue 
B)  decreased gluconeogenesis in liver and kidney cells 
C)  decreased ketogenesis in liver cells 
D)  protein degradation in skeletal muscle

Question 16

What are the concentrations of glucose that would be expected of a healthy individual after an 8-hour fast and after consuming a large soft pretzel?

Accepted Answer

A)  80 mg/dL; 130 mg/dL 
B)  130 mg/dL; 180 mg/dL 
C)  75 mg/dL; 100 mg/dL 
D)  125 mg/dL; 75 mg/dL 
A)  80 mg/dL; 130 mg/dL 
B)  130 mg/dL; 180 mg/dL 
C)  75 mg/dL; 100 mg/dL 
D)  125 mg/dL; 75 mg/dL

Question 17

This is a Western blot of wild-type neurons after exposure to leptin.Choose the sample (A,B,C,or D)that represents the expected data for POMC neurons and explain the reason for your choice.

Accepted Answer

Sample B represents the data f

Question 18

Leptin is a

Accepted Answer

A)  mutated form of insulin. 
B)  hormone receptor expressed in adipocytes. 
C)  adipocyte peptide hormone. 
D)  recessive gene that causes obesity. 
A)  mutated form of insulin. 
B)  hormone receptor expressed in adipocytes. 
C)  adipocyte peptide hormone. 
D)  recessive gene that causes obesity.

Question 19

Which of the following is secreted by visceral fat?

Accepted Answer

A)  glucagon 
B)  adipokines 
C)  somatostatin 
D)  phosphocreatine 
A)  glucagon 
B)  adipokines 
C)  somatostatin 
D)  phosphocreatine

Question 20

The numerical value of a food that indicates how quickly glucose is released into the blood is called the

Accepted Answer

A)  calorie. 
B)  GRP (glucose-release point). 
C)  set point. 
D)  glycemic index. 
A)  calorie. 
B)  GRP (glucose-release point). 
C)  set point. 
D)  glycemic index.

Exam 19: Metabolic Integration

PPARs have a variety of functions in lipid metabolism that include all EXCEPT

Anorexigenic neurons express the __________ receptor.

Are thiazolidinediones agonists or antagonists of PPAR ?

What is the fuel source for ATP production that is used in a 200-meter sprint?

Fad diets may lead to biochemical outcomes that are unfavorable.Which diet may lead to ketoacidosis?

How can hormone(s)cause the upregulation of the glucose transporter type 4 protein in liver and adipose cells?

Differentiate the roles of the two different phosphorylation sites of insulin receptor substrate 1 (IRS1).Include the specific amino acids that are phosphorylated as well as the signaling pathway involved in your answer.

A patient has been diagnosed with metabolic syndrome.To establish the diagnosis,the doctor likely performed several tests.A test that the doctor was UNLIKELY to perform would be

If the bottom curve in this experiment represents the results from a normal human,the top curve represent the results from a human with what disease?

A lack of energy balance may lead to

Which of the following is unlikely to affect metabolic homeostasis?

What is the physiological importance of PPAR signaling in liver cells after overnight fasting?

When calories consumed/day is equal to the calories expended/day,a person is considered to have a(n)__________.Describe the role of leptin in this process.

Which of the following changes in metabolic flux would be expected to occur during long periods without food?

What are the concentrations of glucose that would be expected of a healthy individual after an 8-hour fast and after consuming a large soft pretzel?

This is a Western blot of wild-type neurons after exposure to leptin.Choose the sample (A,B,C,or D)that represents the expected data for POMC neurons and explain the reason for your choice.

Leptin is a

Which of the following is secreted by visceral fat?

The numerical value of a food that indicates how quickly glucose is released into the blood is called the

Principles of Biochemistry

Physical Biochemistry: Energy Conversion,water,and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Oxidative Phosphorylation

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Dna Replication, repair, and Recombination

Rna Synthesis, processing, and Gene Silencing

Protein Synthesis, posttranslational Modification, and Transport

Gene Regulation

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