Question 1

Which statement is true of the mitochondrial electron transport system?

Accepted Answer

A)  All the electron carriers are located in enzyme complexes. 
B)  All the electrons in the chain end up on O2 to produce water. 
C)  The pH drops in the mitochondria as electrons pass through the system. 
D)  Protons are pumped from the inner membrane space to the mitochondrial matrix during the electron transfer. 
A)  All the electron carriers are located in enzyme complexes. 
B)  All the electrons in the chain end up on O2 to produce water. 
C)  The pH drops in the mitochondria as electrons pass through the system. 
D)  Protons are pumped from the inner membrane space to the mitochondrial matrix during the electron transfer.

Question 2

As electrons from NADH pass through the electron transport system,

Accepted Answer

A)  the oxidized form of ADP is reduced to ATP. 
B)  the reduction potential of the mitochondria becomes more thermodynamically favorable. 
C)  the resulting electron gradient is used to make ATP. 
D)  protons are pumped across the mitochondrial membrane to create a pH gradient. 
A)  the oxidized form of ADP is reduced to ATP. 
B)  the reduction potential of the mitochondria becomes more thermodynamically favorable. 
C)  the resulting electron gradient is used to make ATP. 
D)  protons are pumped across the mitochondrial membrane to create a pH gradient.

Question 3

The last enzyme in the electron transport system,where O2 is reduced to water,is called

Accepted Answer

A)  NADH-ubiquinone oxidoreductase. 
B)  ATP synthase. 
C)  ubiquinone cytochrome c oxidoreductase. 
D)  cytochrome c oxidase. 
A)  NADH-ubiquinone oxidoreductase. 
B)  ATP synthase. 
C)  ubiquinone cytochrome c oxidoreductase. 
D)  cytochrome c oxidase.

Question 4

Studies of the inner mitochondrial membrane reveal its composition to be approximately 20% lipid bilayer and 80% protein.What is true of these proteins?

Accepted Answer

A)  Abundant collagen proteins form connective tissues to strengthen the membrane against the pH gradient. 
B)  High levels of proteins are required to metabolize glucose in the glycolysis pathway for rapid energy production. 
C)  The proteins form highly folded cristae structures. 
D)  The proteins are largely electron transport complexes and ATP synthase enzymes. 
A)  Abundant collagen proteins form connective tissues to strengthen the membrane against the pH gradient. 
B)  High levels of proteins are required to metabolize glucose in the glycolysis pathway for rapid energy production. 
C)  The proteins form highly folded cristae structures. 
D)  The proteins are largely electron transport complexes and ATP synthase enzymes.

Question 5

What is the driving force for ATP synthesis by the ATP synthase enzyme?

Accepted Answer

A)  The electron transfers through the protein complexes. 
B)  ADP + Pi  ATP 
C)  The oxidation of NADH to NAD+. 
D)  The pH gradient across the inner mitochondrial membrane. 
A)  The electron transfers through the protein complexes. 
B)  ADP + Pi  ATP 
C)  The oxidation of NADH to NAD+. 
D)  The pH gradient across the inner mitochondrial membrane.

Question 6

Submitochondrial particles are inside-out pieces of the inner mitochondrial membrane formed through the sonication of mitochondria.Draw a diagram of these inside-out particles clearly showing (A)where electron transport from NADH occurs,(B)the direction of proton pumping,(C)the location of ATP synthesis,and (D)where O2 reacts.

Accepted Answer

Question 7

The free energy released from the electron transport system reaction NADH + 1/2 O2 + H+   H2O + NAD+ is   '= -220 kJ/mol.How many moles of ATP could theoretically be made assuming 100% efficiency in energy coupling through the chemiosmotic theory,and that ADP+Pi  ATP   '= 30.5 kJ/mol?

Accepted Answer

220 kJ/mol / 30.5 kJ

Question 8

The __________ causes the catalytic headpiece of ATP synthase to change conformation.

Accepted Answer

A)  rotation of the circle of the  3   3 subunits 
B)  movement of the circle of ~10 c subunits 
C)  interaction with the rotating central  Subunit 
D)  binding of ADP and Pi 
A)  rotation of the circle of the  3   3 subunits 
B)  movement of the circle of ~10 c subunits 
C)  interaction with the rotating central  Subunit 
D)  binding of ADP and Pi

Question 9

What is the fate of NADH after it donates its electrons to the electron transport system?

Accepted Answer

A)  NAD+ is excreted from the cell and sent to the liver for final degradation. 
B)  NADH is used for cellular biosynthesis. 
C)  NAD+ is re-reduced by the TCA cycle or glycolysis and returns to electron transport system, where the process is repeated. 
D)  NAD+ is fed into the TCA cycle for oxidation of CO2. 
A)  NAD+ is excreted from the cell and sent to the liver for final degradation. 
B)  NADH is used for cellular biosynthesis. 
C)  NAD+ is re-reduced by the TCA cycle or glycolysis and returns to electron transport system, where the process is repeated. 
D)  NAD+ is fed into the TCA cycle for oxidation of CO2.

Question 10

Use the table below to answer the question.  
In the direction indicated,which of the following reactions are thermodynamically favored?
I.NAD+ + H2O  O2 + NADH
II.FADH2 + H2O  O2 + FAD
III.NADH + O2  H2O + NAD+

Accepted Answer

A)  I and II 
B)  I and III 
C)  I, II, and III 
D)  III only 
A)  I and II 
B)  I and III 
C)  I, II, and III 
D)  III only

Question 11

The first enzyme in the electron transport system is referred to as complex I,otherwise known as

Accepted Answer

A)  ATP synthase. 
B)  NADH-ubiquinone oxidoreductase. 
C)  succinate dehydrogenase. 
D)  cytochrome c oxidase. 
A)  ATP synthase. 
B)  NADH-ubiquinone oxidoreductase. 
C)  succinate dehydrogenase. 
D)  cytochrome c oxidase.

Question 12

For each molecule below,list the number of ATP obtained assuming that the electron transport chain and oxidative phosphorylation are active.
NADH (from the TCA cycle)
FADH2 (from the TCA cycle)
NADH (from the cytoplasm,malate aspartate shuttle)
NAD+ (from the mitochondria)

Accepted Answer

NADH (from the TCA cycle)2.5
F

Question 13

For one electron entering the electron transport chain at complex I,how many times is it handed off between redox active cofactors on its way through the enzyme complexes to end up on O2?

Accepted Answer

A)  ~2000 
B)  ~200 
C)  ~20 
D)  ~2 
A)  ~2000 
B)  ~200 
C)  ~20 
D)  ~2

Question 14

How many ATPs are obtained from one acetyl-CoA run once through the TCA cycle,assuming that all resulting NADH and FADH2 is used by the electron transport chain and oxidative phosphorylation to make ATP?

Accepted Answer

A)  6.5 
B)  9 
C)  10 
D)  11 
A)  6.5 
B)  9 
C)  10 
D)  11

Question 15

If the mitochondrial ATP synthase were inhibited,but the electron transport chain was allowed to run continuously,the pH of the cytoplasm would

Accepted Answer

A)  decrease. 
B)  increase. 
C)  remain unchanged. 
D)  increase immediately and then decrease. 
A)  decrease. 
B)  increase. 
C)  remain unchanged. 
D)  increase immediately and then decrease.

Question 16

The ATP synthase enzyme contains a central stalk embedded in the mitochondrial membrane.What part of this stalk rotates?

Accepted Answer

A)  the  3   3 ring 
B)  the F1 subunit 
C)  the d, h, and OSCP subunits 
D)  the ring of c subunits 
A)  the  3   3 ring 
B)  the F1 subunit 
C)  the d, h, and OSCP subunits 
D)  the ring of c subunits

Question 17

Approximately how many more ATPs are made from one glucose molecule under aerobic conditions with oxidative phosphorylation than under anaerobic conditions?

Accepted Answer

A)  0 
B)  2 
C)  30 
D)  104 
A)  0 
B)  2 
C)  30 
D)  104

Question 18

The role of brown adipose tissue is to

Accepted Answer

A)  efficiently generate ATP from fat tissue. 
B)  metabolize excess fat calories. 
C)  store excess calories as fat. 
D)  generate heat for the organism. 
A)  efficiently generate ATP from fat tissue. 
B)  metabolize excess fat calories. 
C)  store excess calories as fat. 
D)  generate heat for the organism.

Which statement is true of the mitochondrial electron transport system?

As electrons from NADH pass through the electron transport system,

The last enzyme in the electron transport system,where O₂ is reduced to water,is called

Studies of the inner mitochondrial membrane reveal its composition to be approximately 20% lipid bilayer and 80% protein.What is true of these proteins?

What is the driving force for ATP synthesis by the ATP synthase enzyme?

The free energy released from the electron transport system reaction NADH + ¹/₂ O₂ + H⁺ H₂O + NAD⁺ is '= -220 kJ/mol.How many moles of ATP could theoretically be made assuming 100% efficiency in energy coupling through the chemiosmotic theory,and that ADP+P_i ATP '= 30.5 kJ/mol?

The __________ causes the catalytic headpiece of ATP synthase to change conformation.

What is the fate of NADH after it donates its electrons to the electron transport system?

Use the table below to answer the question. In the direction indicated,which of the following reactions are thermodynamically favored? I.NAD⁺ + H₂O O₂ + NADH II.FADH₂ + H₂O O₂ + FAD III.NADH + O₂ H₂O + NAD⁺

The first enzyme in the electron transport system is referred to as complex I,otherwise known as

For each molecule below,list the number of ATP obtained assuming that the electron transport chain and oxidative phosphorylation are active. NADH (from the TCA cycle) FADH₂ (from the TCA cycle) NADH (from the cytoplasm,malate aspartate shuttle) NAD⁺ (from the mitochondria)

For one electron entering the electron transport chain at complex I,how many times is it handed off between redox active cofactors on its way through the enzyme complexes to end up on O₂?

How many ATPs are obtained from one acetyl-CoA run once through the TCA cycle,assuming that all resulting NADH and FADH₂ is used by the electron transport chain and oxidative phosphorylation to make ATP?

If the mitochondrial ATP synthase were inhibited,but the electron transport chain was allowed to run continuously,the pH of the cytoplasm would

The ATP synthase enzyme contains a central stalk embedded in the mitochondrial membrane.What part of this stalk rotates?

Approximately how many more ATPs are made from one glucose molecule under aerobic conditions with oxidative phosphorylation than under anaerobic conditions?

The role of brown adipose tissue is to

Principles of Biochemistry

Physical Biochemistry: Energy Conversion,water,and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Metabolic Integration

Dna Replication, repair, and Recombination

Rna Synthesis, processing, and Gene Silencing

Protein Synthesis, posttranslational Modification, and Transport

Gene Regulation

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Exam 11: Oxidative Phosphorylation

Which statement is true of the mitochondrial electron transport system?

As electrons from NADH pass through the electron transport system,

The last enzyme in the electron transport system,where O2 is reduced to water,is called

Studies of the inner mitochondrial membrane reveal its composition to be approximately 20% lipid bilayer and 80% protein.What is true of these proteins?

What is the driving force for ATP synthesis by the ATP synthase enzyme?

The free energy released from the electron transport system reaction NADH + 1/2 O2 + H+ H2O + NAD+ is '= -220 kJ/mol.How many moles of ATP could theoretically be made assuming 100% efficiency in energy coupling through the chemiosmotic theory,and that ADP+Pi ATP '= 30.5 kJ/mol?

The __________ causes the catalytic headpiece of ATP synthase to change conformation.

What is the fate of NADH after it donates its electrons to the electron transport system?

Use the table below to answer the question. In the direction indicated,which of the following reactions are thermodynamically favored? I.NAD+ + H2O O2 + NADH II.FADH2 + H2O O2 + FAD III.NADH + O2 H2O + NAD+

The first enzyme in the electron transport system is referred to as complex I,otherwise known as

For each molecule below,list the number of ATP obtained assuming that the electron transport chain and oxidative phosphorylation are active. NADH (from the TCA cycle) FADH2 (from the TCA cycle) NADH (from the cytoplasm,malate aspartate shuttle) NAD+ (from the mitochondria)

For one electron entering the electron transport chain at complex I,how many times is it handed off between redox active cofactors on its way through the enzyme complexes to end up on O2?

How many ATPs are obtained from one acetyl-CoA run once through the TCA cycle,assuming that all resulting NADH and FADH2 is used by the electron transport chain and oxidative phosphorylation to make ATP?

If the mitochondrial ATP synthase were inhibited,but the electron transport chain was allowed to run continuously,the pH of the cytoplasm would

The ATP synthase enzyme contains a central stalk embedded in the mitochondrial membrane.What part of this stalk rotates?

Approximately how many more ATPs are made from one glucose molecule under aerobic conditions with oxidative phosphorylation than under anaerobic conditions?

The role of brown adipose tissue is to

Principles of Biochemistry

Physical Biochemistry: Energy Conversion,water,and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Metabolic Integration

Dna Replication, repair, and Recombination

Rna Synthesis, processing, and Gene Silencing

Protein Synthesis, posttranslational Modification, and Transport

Gene Regulation

Filters

The last enzyme in the electron transport system,where O₂ is reduced to water,is called

The free energy released from the electron transport system reaction NADH + ¹/₂ O₂ + H⁺ H₂O + NAD⁺ is '= -220 kJ/mol.How many moles of ATP could theoretically be made assuming 100% efficiency in energy coupling through the chemiosmotic theory,and that ADP+P_i ATP '= 30.5 kJ/mol?

Use the table below to answer the question. In the direction indicated,which of the following reactions are thermodynamically favored? I.NAD⁺ + H₂O O₂ + NADH II.FADH₂ + H₂O O₂ + FAD III.NADH + O₂ H₂O + NAD⁺

For each molecule below,list the number of ATP obtained assuming that the electron transport chain and oxidative phosphorylation are active. NADH (from the TCA cycle) FADH₂ (from the TCA cycle) NADH (from the cytoplasm,malate aspartate shuttle) NAD⁺ (from the mitochondria)

For one electron entering the electron transport chain at complex I,how many times is it handed off between redox active cofactors on its way through the enzyme complexes to end up on O₂?

How many ATPs are obtained from one acetyl-CoA run once through the TCA cycle,assuming that all resulting NADH and FADH₂ is used by the electron transport chain and oxidative phosphorylation to make ATP?