Question 1

Which of the following undergoes the most rapid acylation upon treatment with acetyl chloride and AlCl3?

Accepted Answer

A) benzene 
B) toluene 
C) chlorobenzene 
D) 1,4-dichlorobenzene 
A) benzene 
B) toluene 
C) chlorobenzene 
D) 1,4-dichlorobenzene

Question 2

Which of the following is the reactive intermediate formed in the electrophilic nitration of nitrobenzene with HNO3 and H2SO4?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 3

What is the role of AlCl3 in Friedel Crafts acylations using acid chlorides?

Accepted Answer

A) Lewis acid 
B) electrophile 
C) base 
D) nucleophile 
A) Lewis acid 
B) electrophile 
C) base 
D) nucleophile

Question 4

Which of the following sets of substituents are all deactivating groups in electrophilic aromatic substitution reactions?

Accepted Answer

A) Cl, OH, CH2CH3 
B) CH3, Br, COCH3 
C) CH3, NH2, OH 
D) COCH3, NO2, Br 
A) Cl, OH, CH2CH3 
B) CH3, Br, COCH3 
C) CH3, NH2, OH 
D) COCH3, NO2, Br

Question 5

In electrophilic aromatic substitution reactions, the following molecule are considered to be ______ reactive than benzene

Accepted Answer

The answer of In electrophilic aromatic substitution reactions, the following...

Question 6

What is the major organic product obtained from the following reaction?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 7

Which of the following substituents is ortho/para directing and deactivating in electrophilic aromatic substitution reactions?

Accepted Answer

A) COCH3 
B) NH3 
C) Br 
D) CH2CH3 
A) COCH3 
B) NH3 
C) Br 
D) CH2CH3

Question 8

What is the major organic product obtained from the following reaction?

Accepted Answer

The answer of What is the major organic product obtained...

Question 9

What is the major organic product obtained from the following reaction?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 10

Which of the following cannot be prepared from benzene in two synthetic steps?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 11

What is the major organic product obtained from the following reaction?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 12

All of the following can act as an electrophile in an electrophilic aromatic substitution reaction.
SO3 (CH3)3C+ NO2+

Accepted Answer

A) True 
 B)False

Question 13

Provide the structure (a single resonance contributor) of the key intermediate in the following reaction
.

Accepted Answer

The answer of Provide the structure (a single resonance contributor)...

Question 14

What is the major organic product obtained from the following sequence of reactions?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 15

Which of the following is not true about benzynes?

Accepted Answer

A) They are planar 
B) They are formed upon dehydrohalogenation of aryl halides 
C) They are aromatic 
D) They are intermediates in nucleophilic aromatic substitution reaction which take place by an addition-elimination mechanism 
A) They are planar 
B) They are formed upon dehydrohalogenation of aryl halides 
C) They are aromatic 
D) They are intermediates in nucleophilic aromatic substitution reaction which take place by an addition-elimination mechanism

Question 16

Which of the following is the reactive intermediate formed in the electrophilic bromination of toluene with Br2, FeBr3?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 17

MATCHING
MATCH a structure or term from the following list with each description below. Place the letter of the structure or term in the blank to the left of the description.
-______ The reactive electrophile in Friedel-Crafts acylation reactions.

Accepted Answer

A) benzyne 
B) "+NO2" 
C) R3C+ 
D) electron-donating 
E) "+NO"
F)Meisenheimer complex
G) 
H)electron-withdrawing 
A) benzyne 
B) "+NO2" 
C) R3C+ 
D) electron-donating 
E) "+NO"
F)Meisenheimer complex
G) 
H)electron-withdrawing

Question 18

The number of mononitro products that can be produced when the following reactant is treated with nitric and sulfuric acids is _______.

Accepted Answer

The answer of The number of mononitro products that can...

Question 19

What is the electrophile in the reaction of benzene with a mixture of nitric acid and sulfuric acid?

Accepted Answer

A) HONO 
B) NO+ 
C) NO2+ 
D) benzene 
A) HONO 
B) NO+ 
C) NO2+ 
D) benzene

Question 20

What type of intermediate is formed upon treatment of 1-chloro-2,4-dinitrobenzene with sodium hydroxide to give 2,4-dinitrophenol?

Accepted Answer

A) Meisenheimer complex 
B) benzyne 
C) cyclohexadienyl cation 
D) benzyl radical 
A) Meisenheimer complex 
B) benzyne 
C) cyclohexadienyl cation 
D) benzyl radical

Exam 22: Reactions of Benzene and Its Derivatives

Which of the following undergoes the most rapid acylation upon treatment with acetyl chloride and AlCl3?

Which of the following is the reactive intermediate formed in the electrophilic nitration of nitrobenzene with HNO3 and H2SO4?

What is the role of AlCl3 in Friedel Crafts acylations using acid chlorides?

Which of the following sets of substituents are all deactivating groups in electrophilic aromatic substitution reactions?

In electrophilic aromatic substitution reactions, the following molecule are considered to be ______ reactive than benzene

What is the major organic product obtained from the following reaction?

Which of the following substituents is ortho/para directing and deactivating in electrophilic aromatic substitution reactions?

What is the major organic product obtained from the following reaction?

What is the major organic product obtained from the following reaction?

Which of the following cannot be prepared from benzene in two synthetic steps?

What is the major organic product obtained from the following reaction?

All of the following can act as an electrophile in an electrophilic aromatic substitution reaction. SO3 (CH3)3C+ NO2+

Provide the structure (a single resonance contributor) of the key intermediate in the following reaction .

What is the major organic product obtained from the following sequence of reactions?

Which of the following is not true about benzynes?

Which of the following is the reactive intermediate formed in the electrophilic bromination of toluene with Br2, FeBr3?

MATCHING MATCH a structure or term from the following list with each description below. Place the letter of the structure or term in the blank to the left of the description. -______ The reactive electrophile in Friedel-Crafts acylation reactions.

The number of mononitro products that can be produced when the following reactant is treated with nitric and sulfuric acids is _______.

What is the electrophile in the reaction of benzene with a mixture of nitric acid and sulfuric acid?

What type of intermediate is formed upon treatment of 1-chloro-2,4-dinitrobenzene with sodium hydroxide to give 2,4-dinitrophenol?

Covalent Bonding and Shapes of Molecules

Alkanes and Cycloalkanes

Stereoisomerism and Chirality

Acids and Bases

Alkenes: Bonding, Nomenclature, and Properties

Reactions of Alkenes

Alkynes

Haloalkanes, Halogenation, and Radical Reactions

Nucleophilic Substitution and Beta-Elimination

Alcohols

Ethers, Epoxides, and Sulfides

Infrared Spectroscopy

Nuclear Magnetic Resonance Spectroscopy

Mass Spectrometry

An Introduction to Organometallic Compounds

Aldehydes and Ketones

Carboxylic Acids

Functional Derivatives of Carboxylic Acids

Enolate Anions and Enamines

Dienes, Conjugated Systems, and Pericyclic Reactions

Benzene and the Concept of Aromaticity

Amines

Catalytic Carbon-Carbon Bond Formation

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids

Organic Polymer Chemistry

Filters

Which of the following undergoes the most rapid acylation upon treatment with acetyl chloride and AlCl₃?

Which of the following is the reactive intermediate formed in the electrophilic nitration of nitrobenzene with HNO₃ and H₂SO₄?

What is the role of AlCl₃ in Friedel Crafts acylations using acid chlorides?

All of the following can act as an electrophile in an electrophilic aromatic substitution reaction. SO₃(CH₃)₃C⁺ NO₂⁺

Which of the following is the reactive intermediate formed in the electrophilic bromination of toluene with Br₂, FeBr₃?