Question 1

A drug will generally inhibit multiplication of the bacteria so that the patient's immune defense mechanisms are no longer overwhelmed when:

Accepted Answer

A)  All the debris and necrotic cells are removed. 
B)  The drug concentration exceeds the MIC for the microbe. 
C)  The patient is not infected with a gram-negative rod. 
D)  Two synergistic drugs are used to kill the bacteria. 
A)  All the debris and necrotic cells are removed. 
B)  The drug concentration exceeds the MIC for the microbe. 
C)  The patient is not infected with a gram-negative rod. 
D)  Two synergistic drugs are used to kill the bacteria.

Question 2

What concentrations of antibiotics are tested in minimal inhibitory concentrations (MICs)?

Accepted Answer

A)  Serial fivefold dilution concentrations are tested. 
B)  Serial tenfold dilution concentrations are tested. 
C)  Serial onefold dilution concentrations are tested. 
D)  Serial twofold dilution concentrations are tested. 
A)  Serial fivefold dilution concentrations are tested. 
B)  Serial tenfold dilution concentrations are tested. 
C)  Serial onefold dilution concentrations are tested. 
D)  Serial twofold dilution concentrations are tested.

Question 3

The minimal inhibitory concentration (MIC)is:

Accepted Answer

A)  The lowest antibiotic concentration to slow the growth of an organism. 
B)  The highest antibiotic concentration to slow the growth of an organism. 
C)  The lowest antibiotic concentration to inhibit the growth of an organism. 
D)  The highest antibiotic concentration to inhibit the growth of an organism. 
A)  The lowest antibiotic concentration to slow the growth of an organism. 
B)  The highest antibiotic concentration to slow the growth of an organism. 
C)  The lowest antibiotic concentration to inhibit the growth of an organism. 
D)  The highest antibiotic concentration to inhibit the growth of an organism.

Question 4

What principle do most current automated antimicrobial susceptibility instruments use to read growth?

Accepted Answer

A)  Turbidimetric detection 
B)  Turbidity suppression 
C)  Hydrolysis of a fluorogenic growth substrate 
D)  Carbon dioxide concentration 
A)  Turbidimetric detection 
B)  Turbidity suppression 
C)  Hydrolysis of a fluorogenic growth substrate 
D)  Carbon dioxide concentration

Question 5

In this method of antimicrobial susceptibility testing,specific volumes of various concentrations of antimicrobial solutions are dispensed into premeasured volumes of molten and cooled agar,which is subsequently poured into standard Petri dishes.Organisms are inoculated onto the plate.What type of antimicrobial susceptibility testing is this?

Accepted Answer

A)  Macrodilution 
B)  Broth dilution 
C)  Disk diffusion 
D)  Agar dilution 
A)  Macrodilution 
B)  Broth dilution 
C)  Disk diffusion 
D)  Agar dilution

Exam 13: Antimicrobial Susceptibility Testing

A drug will generally inhibit multiplication of the bacteria so that the patient's immune defense mechanisms are no longer overwhelmed when:

What concentrations of antibiotics are tested in minimal inhibitory concentrations (MICs)?

The minimal inhibitory concentration (MIC)is:

What principle do most current automated antimicrobial susceptibility instruments use to read growth?

Bacterial Cell Structure, physiology, Metabolism, and Genetics

Host-Parasite Interaction

Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Infected Materials

Use of Colonial Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antibiotic Mechanisms of Action and Resistance

Staphylococci

Streptococcus, enterococcus, and Other Catalase-Negative Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio,aeromonas,plesiomonas and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

Spirochetes

Chlamydia and Rickettsia

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Other Nontuberculosis Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Clinical Virology

Agents of Bioterror

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Diseases

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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