Question 1

What is used as the indicator in a complement fixation (CF)test?

Accepted Answer

A)  Latex particles 
B)  Horse red blood cells 
C)  Rabbit red blood cells 
D)  Sheep red blood cells 
A)  Latex particles 
B)  Horse red blood cells 
C)  Rabbit red blood cells 
D)  Sheep red blood cells D

Question 2

In precipitation assays,what is the precipitate made out of?

Accepted Answer

A)  Complement and protein complex 
B)  Antibody and protein complex 
C)  Antigen and antibody complex 
D)  Antigen and protein complex 
A)  Complement and protein complex 
B)  Antibody and protein complex 
C)  Antigen and antibody complex 
D)  Antigen and protein complex C

Question 3

What patients are highly susceptible to cytomegalovirus (CMV)infections?

Accepted Answer

A)  Immunosuppressed 
B)  Immunocompetent 
C)  Males 
D)  Females 
A)  Immunosuppressed 
B)  Immunocompetent 
C)  Males 
D)  Females A

Question 4

If a baby were exposed to hepatitis A in utero,what type of antibodies would be produced?

Accepted Answer

A)  IgD 
B)  IgE 
C)  IgG 
D)  IgM 
A)  IgD 
B)  IgE 
C)  IgG 
D)  IgM

Question 5

All of the following are congenital defects produced by rubella EXCEPT:

Accepted Answer

A)  Deafness 
B)  Blindness 
C)  Cataracts 
D)  Congenital heart disease 
A)  Deafness 
B)  Blindness 
C)  Cataracts 
D)  Congenital heart disease

Question 6

The advantages of latex agglutination include all the following EXCEPT:

Accepted Answer

A)  Availability of good quality reagents in complete kit form 
B)  Good sensitivity 
C)  Ease of performance 
D)  Subjectivity in reading endpoints 
A)  Availability of good quality reagents in complete kit form 
B)  Good sensitivity 
C)  Ease of performance 
D)  Subjectivity in reading endpoints

Question 7

Indirect agglutination is also referred to as:

Accepted Answer

A)  Passive agglutination 
B)  Incomplete agglutination 
C)  Active agglutination 
D)  Flocculation 
A)  Passive agglutination 
B)  Incomplete agglutination 
C)  Active agglutination 
D)  Flocculation

Question 8

What is ASO used for?

Accepted Answer

A)  To demonstrate serologic response to streptococcal antigen 
B)  To determine if a strep has been lysogenized 
C)  To determine if a strep produces a hemolysin 
D)  To demonstrate serologic response to Streptococcus pyogenes 
A)  To demonstrate serologic response to streptococcal antigen 
B)  To determine if a strep has been lysogenized 
C)  To determine if a strep produces a hemolysin 
D)  To demonstrate serologic response to Streptococcus pyogenes

Question 9

Which hepatitis virus leads to chronic hepatitis and cirrhosis,often requiring a liver transplant,and causes a high risk for development of liver cancer?

Accepted Answer

A)  Hepatitis A 
B)  Hepatitis D 
C)  Hepatitis C 
D)  Hepatitis E 
A)  Hepatitis A 
B)  Hepatitis D 
C)  Hepatitis C 
D)  Hepatitis E

Question 10

Latex agglutination kits are available for all the following bacterial antigens EXCEPT:

Accepted Answer

A)  Cryptococcus neoformans 
B)  Neisseria meningitidis 
C)  Haemophilus influenzae 
D)  Streptococcus pneumoniae 
A)  Cryptococcus neoformans 
B)  Neisseria meningitidis 
C)  Haemophilus influenzae 
D)  Streptococcus pneumoniae

Question 11

Which test is a confirmatory test of enzyme-linked immunosorbent assay (ELISA)HIV?

Accepted Answer

A)  Enzyme immunoassay (EI
A)  
B)  Northern blot 
C)  Southern blot 
D)  Western blot 
A)  Enzyme immunoassay (EI
A)  
B)  Northern blot 
C)  Southern blot 
D)  Western blot

Question 12

What is the name of the test used to detect rickettsial agents?

Accepted Answer

A)  Levy-Jennings 
B)  Mueller-Hinton 
C)  Weil-Felix 
D)  Watson-Crick 
A)  Levy-Jennings 
B)  Mueller-Hinton 
C)  Weil-Felix 
D)  Watson-Crick

Question 13

How is hepatitis B transmitted?

Accepted Answer

A)  Contaminated food and water 
B)  Blood and body fluids 
C)  Respiratory droplets 
D)  Airborne 
A)  Contaminated food and water 
B)  Blood and body fluids 
C)  Respiratory droplets 
D)  Airborne

Question 14

Enzyme immunoassay (EIA)differs from immunofluorescent tests by:

Accepted Answer

A)  Using a different fluorescent label 
B)  Using a enzymes and a chromogenic substrate 
C)  Being valid for direct testing only 
D)  All of the above 
A)  Using a different fluorescent label 
B)  Using a enzymes and a chromogenic substrate 
C)  Being valid for direct testing only 
D)  All of the above

Question 15

How does Clostridium difficile produce pseudomembranous colitis and antibiotic-associated diarrhea?

Accepted Answer

A)  Endotoxin 
B)  Hyaluronidase 
C)  Toxin A and toxin B (exotoxins) 
D)  Protease 
A)  Endotoxin 
B)  Hyaluronidase 
C)  Toxin A and toxin B (exotoxins) 
D)  Protease

Question 16

All of the following are antigens present in a hepatitis B infection EXCEPT:

Accepted Answer

A)  HBsAg 
B)  HBcAg 
C)  HBeAg 
D)  VCNA 
A)  HBsAg 
B)  HBcAg 
C)  HBeAg 
D)  VCNA

Question 17

Infection with cytomegalovirus (CMV)in nonimmune pregnant women can cause:

Accepted Answer

A)  Misshapen limbs 
B)  Congenital heart defects 
C)  Liver problems 
D)  Microencephalopathy 
A)  Misshapen limbs 
B)  Congenital heart defects 
C)  Liver problems 
D)  Microencephalopathy

Question 18

Streptozyme detects all of the following EXCEPT:

Accepted Answer

A)  Streptokinase 
B)  Hyaluronidase 
C)  Streptolysin-O 
D)  Hippurate hydrolysis 
A)  Streptokinase 
B)  Hyaluronidase 
C)  Streptolysin-O 
D)  Hippurate hydrolysis

Question 19

What is the earliest serologic marker detected in hepatitis B?

Accepted Answer

A)  HAV 
B)  HBsAg 
C)  HBcAg 
D)  HBeAg 
A)  HAV 
B)  HBsAg 
C)  HBcAg 
D)  HBeAg

Question 20

What can cause a false-positive IgM serologic test?

Accepted Answer

A)  The presence of IgG antibodies 
B)  The presence of rheumatoid factors 
C)  The presence of Rh factor 
D)  The presence of cytomegalovirus (CMV) antibodies 
A)  The presence of IgG antibodies 
B)  The presence of rheumatoid factors 
C)  The presence of Rh factor 
D)  The presence of cytomegalovirus (CMV) antibodies

Exam 10: Immunodiagnosis of Infectious Diseases

What is used as the indicator in a complement fixation (CF)test?

In precipitation assays,what is the precipitate made out of?

What patients are highly susceptible to cytomegalovirus (CMV)infections?

If a baby were exposed to hepatitis A in utero,what type of antibodies would be produced?

All of the following are congenital defects produced by rubella EXCEPT:

The advantages of latex agglutination include all the following EXCEPT:

Indirect agglutination is also referred to as:

What is ASO used for?

Which hepatitis virus leads to chronic hepatitis and cirrhosis,often requiring a liver transplant,and causes a high risk for development of liver cancer?

Latex agglutination kits are available for all the following bacterial antigens EXCEPT:

Which test is a confirmatory test of enzyme-linked immunosorbent assay (ELISA)HIV?

What is the name of the test used to detect rickettsial agents?

How is hepatitis B transmitted?

Enzyme immunoassay (EIA)differs from immunofluorescent tests by:

How does Clostridium difficile produce pseudomembranous colitis and antibiotic-associated diarrhea?

All of the following are antigens present in a hepatitis B infection EXCEPT:

Infection with cytomegalovirus (CMV)in nonimmune pregnant women can cause:

Streptozyme detects all of the following EXCEPT:

What is the earliest serologic marker detected in hepatitis B?

What can cause a false-positive IgM serologic test?

Bacterial Cell Structure, physiology, Metabolism, and Genetics

Host-Parasite Interaction

Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Infected Materials

Use of Colonial Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Applications of Molecular Diagnostics

Antibiotic Mechanisms of Action and Resistance

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, enterococcus, and Other Catalase-Negative Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio,aeromonas,plesiomonas and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

Spirochetes

Chlamydia and Rickettsia

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Other Nontuberculosis Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Clinical Virology

Agents of Bioterror

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Diseases

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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