Exam 10: Nutritional Genomics

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What nutrient should the registered dietician counsel Mrs. G on how to achieve optimal levels in her diet or via supplementation to reduce her risk of such a disease?

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E

What kind of hereditary disease is cystic fibrosis?

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C

As opposed to monogenic diseases, complex diseases such as obesity, diabetes, cancer, and cardiovascular disease are _______________.

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​polygenic

The interaction between drugs and an individual's genome is referred to as:

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A copy of a specific gene situated in a given locus on a chromosome is called a(n):

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Colon cancer risk reduction in humans via intake of cruciferous vegetables is linked to glutathione S-transferase genotype.

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Briefly discuss the connection between folate intake and cancer risk.

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Several cancers have a clearly established genetic inheritance based on mutations in a single gene.

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The recommendation of one diet intervention in response to one polymorphism is likely to be effective.

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What chromosome number is linked to various disease states with nutritional implications including several cancers, type 1 diabetes, and Crohn's disease?

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Since oxidative DNA damage is thought to play a role in carcinogenesis, adequacy of _______________ is suggested to be anti-carcinogenic.

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The APOE gene variant that puts an individual at risk for CVD is also associated with a high risk of what other disease?

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Attention to nutritional genomics and pharmacogenomics has been escalating and this trend is likely to continue in the coming years.

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What year did Gregor Mendel discover the laws of genetics?

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One of the hottest areas of debate regarding the interplay between ethics and genetics has to do with direct-to-consumer marketing of _______________.

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How many genes are in the human genome?

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What chromosomes do human males have?

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The production of RNA from DNA is accomplished by what process?

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Environmental factors play a large role in regulating gene _______________.

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In what year did the International Human Genome Sequencing Consortium publish the finished version of the human genome sequence?

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