Question 1

Which of the following statements is true of heart failure?

Accepted Answer

A)  Usually the right side fails first. 
B)  If the left side of the heart fails, the blood backs up into the pulmonary circulation. 
C)  If the right side of the heart fails, then the left ventricle is unable to remove all the blood from the right side of the heart. 
D)  Left-sided heart failure causes systemic congestion. 
A)  Usually the right side fails first. 
B)  If the left side of the heart fails, the blood backs up into the pulmonary circulation. 
C)  If the right side of the heart fails, then the left ventricle is unable to remove all the blood from the right side of the heart. 
D)  Left-sided heart failure causes systemic congestion.

Question 2

Patients taking antihypertensive agents who have been supine for some time should be slowly raised from that position. They should dangle their legs over the side of the chair and wiggle them before rising to the standing position.

Accepted Answer

A)  Both statements are true. 
B)  Both statements are false. 
C)  The first statement is true; the second statement is false. 
D)  The first statement is false; the second statement is true. 
A)  Both statements are true. 
B)  Both statements are false. 
C)  The first statement is true; the second statement is false. 
D)  The first statement is false; the second statement is true.

Question 3

Which of the following is a β-adrenergic blocking drug that also has a-receptor blocking activity?

Accepted Answer

A)  Atenolol 
B)  Labetalol 
C)  Doxazosin 
D)  Minoxidil 
A)  Atenolol 
B)  Labetalol 
C)  Doxazosin 
D)  Minoxidil

Question 4

β-Adrenergic blockers lower blood pressure primarily by:

Accepted Answer

A)  reducing peripheral resistance. 
B)  decreasing cardiac output. 
C)  lowering plasma volume. 
D)  lowering plasma renin levels. 
A)  reducing peripheral resistance. 
B)  decreasing cardiac output. 
C)  lowering plasma volume. 
D)  lowering plasma renin levels.

Question 5

All of the following agents inhibit platelet function except for which one?

Accepted Answer

A)  Clopidogrel 
B)  Dipyridamole 
C)  Ticlopidine 
D)  Aspirin 
A)  Clopidogrel 
B)  Dipyridamole 
C)  Ticlopidine 
D)  Aspirin

Question 6

The _____ has the fastest rate of depolarization and therefore directs all the other cells of the heart.

Accepted Answer

A)  sinoatrial (S
A) node 
B)  atrioventricular (AV)node 
C)  bundle of His 
D)  Purkinje fibers 
A)  sinoatrial (S
A) node 
B)  atrioventricular (AV)node 
C)  bundle of His 
D)  Purkinje fibers

Question 7

Which of the following is the primary type of drug recommended for patients who have edema or fluid retention with heart failure (HF)?

Accepted Answer

A)  Angiotensin converting enzyme inhibitor 
B)  Angiotensin receptor antagonist 
C)  Beta-blocker 
D)  Aldosterone antagonist 
E)  Diuretic 
A)  Angiotensin converting enzyme inhibitor 
B)  Angiotensin receptor antagonist 
C)  Beta-blocker 
D)  Aldosterone antagonist 
E)  Diuretic

Question 8

Which of the following classes of antiarrhythmics is associated with gingival enlargement?

Accepted Answer

A)  Amiodarone 
B)  Calcium channel blockers 
C)  Disopyramide 
D)  Procainamide 
E)  Quinidine 
A)  Amiodarone 
B)  Calcium channel blockers 
C)  Disopyramide 
D)  Procainamide 
E)  Quinidine

Question 9

One can prevent an attack of angina pectoris by administering nitrous oxide.

Accepted Answer

A) True 
 B)False

Question 10

Which of the following groups of diuretics are called the "puny" diuretics?

Accepted Answer

A)  Thiazide 
B)  Loop 
C)  Potassium-sparing 
D)  Both a and b 
E)  Both b and c 
A)  Thiazide 
B)  Loop 
C)  Potassium-sparing 
D)  Both a and b 
E)  Both b and c

Question 11

Nitroglycerine (NTG)is a(n)_____ that produces relaxation of vascular smooth muscle throughout the body.

Accepted Answer

A)  vasoconstrictor 
B)  vasodilator 
C)  beta-blocker 
D)  angiotensin-converting enzyme inhibitor 
E)  angiotensin receptor blocker 
A)  vasoconstrictor 
B)  vasodilator 
C)  beta-blocker 
D)  angiotensin-converting enzyme inhibitor 
E)  angiotensin receptor blocker

Question 12

_____ should not be given to persons taking potassium supplements because hyperkalemia will occur.

Accepted Answer

A)  Thiazides 
B)  β-Blockers 
C)  Angiotensin-converting enzyme inhibitors (ACEIs) 
D)  Angiotensin receptor blockers (ARBs) 
E)  Calcium channel blockers 
A)  Thiazides 
B)  β-Blockers 
C)  Angiotensin-converting enzyme inhibitors (ACEIs) 
D)  Angiotensin receptor blockers (ARBs) 
E)  Calcium channel blockers

Question 13

In a normally functioning heart, the bundle of His receives its electrical input from the:

Accepted Answer

A)  Purkinje fibers. 
B)  atrioventricular (AV)node. 
C)  sinoatrial (S
A) node. 
D)  cardiac muscle. 
A)  Purkinje fibers. 
B)  atrioventricular (AV)node. 
C)  sinoatrial (S
A) node. 
D)  cardiac muscle.

Question 14

Which β-adrenergic blocking agent has partial agonist activity and causes some b-stimulation while blocking catecholamine action?

Accepted Answer

A)  Atenolol 
B)  Acebutolol 
C)  Metoprolol 
D)  Carvedilol 
A)  Atenolol 
B)  Acebutolol 
C)  Metoprolol 
D)  Carvedilol

Question 15

Which of the following choices are effects of digoxin on the heart?

Accepted Answer

A)  Digoxin accelerates atrioventricular (AV)conduction. 
B)  Digoxin prolongs the refractory period of the atrioventricular (AV)node. 
C)  Digoxin increases the rate of the sinoatrial (S
A) node. 
D)  Both a and b are effects. 
E)  Both b and c are effects. 
A)  Digoxin accelerates atrioventricular (AV)conduction. 
B)  Digoxin prolongs the refractory period of the atrioventricular (AV)node. 
C)  Digoxin increases the rate of the sinoatrial (S
A) node. 
D)  Both a and b are effects. 
E)  Both b and c are effects.

Question 16

There is a danger of _____ if the dose of anticoagulant is too small.

Accepted Answer

A)  embolism 
B)  hemorrhage 
C)  chronic obstructive pulmonary disease 
D)  angina 
A)  embolism 
B)  hemorrhage 
C)  chronic obstructive pulmonary disease 
D)  angina

Question 17

The newest guidelines from the ACC/AHA recommend using HMG-coA reductase inhibitors (statins)as the drugs of first choice for treating patients with atherosclerotic cardiovascular disease based on:

Accepted Answer

A)  a total cholesterol level of over 240 mg/dL. 
B)  a low-density lipoprotein level over 190 mg/dL. 
C)  the patient's estimated 10-year atherosclerotic cardiovascular disease risk. 
D)  poor lifestyle factors such as being overweight and smoking. 
A)  a total cholesterol level of over 240 mg/dL. 
B)  a low-density lipoprotein level over 190 mg/dL. 
C)  the patient's estimated 10-year atherosclerotic cardiovascular disease risk. 
D)  poor lifestyle factors such as being overweight and smoking.

Question 18

When a physician finds out that his female patient wishes to start a family, he decides to change her cholesterol-lowering medication. He changes her medication from:

Accepted Answer

A)  niacin to simvastatin. 
B)  simvastatin to atorvastatin. 
C)  simvastatin to niacin. 
D)  gemfibrozil to candesartan. 
A)  niacin to simvastatin. 
B)  simvastatin to atorvastatin. 
C)  simvastatin to niacin. 
D)  gemfibrozil to candesartan.

Question 19

Which of the following agents can worsen asthma?

Accepted Answer

A)  Propranolol (Inderal) 
B)  Calcium channel blocker 
C)  ACEIs 
D)  Anticholinergics 
A)  Propranolol (Inderal) 
B)  Calcium channel blocker 
C)  ACEIs 
D)  Anticholinergics

Question 20

Common adverse reactions associated with thiazides include:

Accepted Answer

A)  hypokalemia and hypouricemia. 
B)  hyperkalemia and hypouricemia. 
C)  hypokalemia and hyperuricemia. 
D)  hyperkalemia and hyperuricemia. 
A)  hypokalemia and hypouricemia. 
B)  hyperkalemia and hypouricemia. 
C)  hypokalemia and hyperuricemia. 
D)  hyperkalemia and hyperuricemia.

Exam 14: Drugs for the Treatment of Cardiovascular Disease

Which of the following statements is true of heart failure?

Patients taking antihypertensive agents who have been supine for some time should be slowly raised from that position. They should dangle their legs over the side of the chair and wiggle them before rising to the standing position.

Which of the following is a β-adrenergic blocking drug that also has a-receptor blocking activity?

β-Adrenergic blockers lower blood pressure primarily by:

All of the following agents inhibit platelet function except for which one?

The _____ has the fastest rate of depolarization and therefore directs all the other cells of the heart.

Which of the following is the primary type of drug recommended for patients who have edema or fluid retention with heart failure (HF)?

Which of the following classes of antiarrhythmics is associated with gingival enlargement?

One can prevent an attack of angina pectoris by administering nitrous oxide.

Which of the following groups of diuretics are called the "puny" diuretics?

Nitroglycerine (NTG)is a(n)_____ that produces relaxation of vascular smooth muscle throughout the body.

_____ should not be given to persons taking potassium supplements because hyperkalemia will occur.

In a normally functioning heart, the bundle of His receives its electrical input from the:

Which β-adrenergic blocking agent has partial agonist activity and causes some b-stimulation while blocking catecholamine action?

Which of the following choices are effects of digoxin on the heart?

There is a danger of _____ if the dose of anticoagulant is too small.

The newest guidelines from the ACC/AHA recommend using HMG-coA reductase inhibitors (statins)as the drugs of first choice for treating patients with atherosclerotic cardiovascular disease based on:

When a physician finds out that his female patient wishes to start a family, he decides to change her cholesterol-lowering medication. He changes her medication from:

Which of the following agents can worsen asthma?

Common adverse reactions associated with thiazides include:

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