Question 1

The amount of any drug prescribed for a depressed patient should not exceed a _____-day supply.

Accepted Answer

A)  1 
B)  3 
C)  7 
D)  14 
A)  1 
B)  3 
C)  7 
D)  14 C

Question 2

First-generation antipsychotic therapy must often be combined with _____ drugs such as benztropine to control excessive extrapyramidal stimulation.

Accepted Answer

A)  adrenergic 
B)  antiadrenergic 
C)  cholinergic 
D)  anticholinergic 
A)  adrenergic 
B)  antiadrenergic 
C)  cholinergic 
D)  anticholinergic D

Question 3

Which antidepressant drug carries a "black box" warning regarding its potential to cause life-threatening liver failure?

Accepted Answer

A)  Imipramine 
B)  Bupropion 
C)  Nefazodone 
D)  Mirtazapine 
E)  Venlafaxine 
A)  Imipramine 
B)  Bupropion 
C)  Nefazodone 
D)  Mirtazapine 
E)  Venlafaxine C

Question 4

Which of the following are adverse reactions associated with selective serotonin reuptake inhibitors (SSRIs)?

Accepted Answer

A)  Central nervous system (CNS)depression 
B)  Nausea and diarrhea in approximately 15% to 30% of patients 
C)  Xerostomia in 10% to 15% of the population 
D)  Both a and b 
E)  Both b and c 
A)  Central nervous system (CNS)depression 
B)  Nausea and diarrhea in approximately 15% to 30% of patients 
C)  Xerostomia in 10% to 15% of the population 
D)  Both a and b 
E)  Both b and c

Question 5

Which of the following medications is used to treat bipolar depression?

Accepted Answer

A)  Haloperidol 
B)  Lithium 
C)  Clozapine 
D)  Paroxetine 
A)  Haloperidol 
B)  Lithium 
C)  Clozapine 
D)  Paroxetine

Question 6

Of the tricyclic antidepressants listed, which one is most sedating?

Accepted Answer

A)  Imipramine 
B)  Nortriptyline 
C)  Protriptyline 
D)  Desipramine 
E)  Amitriptyline 
A)  Imipramine 
B)  Nortriptyline 
C)  Protriptyline 
D)  Desipramine 
E)  Amitriptyline

Question 7

Dental local anesthetic with vasoconstricting agents must be limited to the cardiac dose for patients taking:

Accepted Answer

A)  selective serotonin reuptake inhibitors (SSRIs). 
B)  serotonin norepinephrine reuptake inhibitors (SNRIs). 
C)  tricyclic antidepressants (TCAs). 
D)  trazodone (Desyrel). 
A)  selective serotonin reuptake inhibitors (SSRIs). 
B)  serotonin norepinephrine reuptake inhibitors (SNRIs). 
C)  tricyclic antidepressants (TCAs). 
D)  trazodone (Desyrel).

Question 8

All antidepressants will carry a boxed warning about the potential for patient suicide.

Accepted Answer

A) True 
 B)False

Question 9

Which of the following are true of second-generation antipsychotics in contrast to first-generation antipsychotics? (Select all that apply.)

Accepted Answer

A)  Second-generation antipsychotics are used more frequently than first-generation antipsychotics. 
B)  Second-generation antipsychotics are better tolerated than first-generation antipsychotics. 
C)  Second-generation antipsychotics are more effective against the negative effects of psychosis than first-generation antipsychotics. 
D)  Second-generation antipsychotics are primarily dopamine antagonists, whereas first-generation antipsychotics were dopamine agonists. 
A)  Second-generation antipsychotics are used more frequently than first-generation antipsychotics. 
B)  Second-generation antipsychotics are better tolerated than first-generation antipsychotics. 
C)  Second-generation antipsychotics are more effective against the negative effects of psychosis than first-generation antipsychotics. 
D)  Second-generation antipsychotics are primarily dopamine antagonists, whereas first-generation antipsychotics were dopamine agonists.

Question 10

Patients taking first-generation antipsychotics can experience severe intermittent temporomandibular joint (TMJ)pain. This pain is a consequence of:

Accepted Answer

A)  hyperalgesia produced by a-adrenergic blockade. 
B)  anticholinergic side effects. 
C)  dislocation of the mandible. 
D)  extrapyramidal side effects. 
A)  hyperalgesia produced by a-adrenergic blockade. 
B)  anticholinergic side effects. 
C)  dislocation of the mandible. 
D)  extrapyramidal side effects.

Question 11

All of the following symptoms are "negative" (passive)symptoms of psychoses except for which one?

Accepted Answer

A)  Flat affect 
B)  Vocalization of feelings of superhuman strength 
C)  Abstract thinking difficult 
D)  Social withdrawal 
E)  Thought and speech impaired 
A)  Flat affect 
B)  Vocalization of feelings of superhuman strength 
C)  Abstract thinking difficult 
D)  Social withdrawal 
E)  Thought and speech impaired

Question 12

Epinephrine should not be used to treat vasomotor collapse in patients taking first-generation antipsychotics because the first-generation antipsychotics are:

Accepted Answer

A)  α-adrenergic stimulators. 
B)  α-adrenergic blockers. 
C)  β-adrenergic stimulators. 
D)  β-adrenergic blockers. 
A)  α-adrenergic stimulators. 
B)  α-adrenergic blockers. 
C)  β-adrenergic stimulators. 
D)  β-adrenergic blockers.

Question 13

The chemoreceptor trigger zone (CTZ)is a site of action for prochlorperazine and promethazine.

Accepted Answer

A) True 
 B)False

Question 14

Extrapyramidal reactions such as an acute spasm of the mandible caused by first-generation antipsychotics such as phenothiazines:

Accepted Answer

A)  can be treated with anticholinergic agents. 
B)  are disorders of muscle control. 
C)  include akathisia. 
D)  All of the above are correct. 
A)  can be treated with anticholinergic agents. 
B)  are disorders of muscle control. 
C)  include akathisia. 
D)  All of the above are correct.

Question 15

First-generation antipsychotics would have little effect on which of the following symptoms of psychosis?

Accepted Answer

A)  Delusions 
B)  Unwanted thoughts 
C)  Flat affect 
D)  Agitation 
E)  Disorganized behavior 
A)  Delusions 
B)  Unwanted thoughts 
C)  Flat affect 
D)  Agitation 
E)  Disorganized behavior

Question 16

Second-generation antipsychotics have fewer side effects than first-generation antipsychotics.

Accepted Answer

A) True 
 B)False

Question 17

Which of the following second-generation antipsychotics is associated with agranulocytosis?

Accepted Answer

A)  Aripiprazole 
B)  Clozapine 
C)  Quetiapine 
D)  Risperidone 
E)  Ziprasidone 
A)  Aripiprazole 
B)  Clozapine 
C)  Quetiapine 
D)  Risperidone 
E)  Ziprasidone

Question 18

Which of the following agents is classified as an antipsychotic?

Accepted Answer

A)  Celexa 
B)  Cephalexin 
C)  Zyprexa 
D)  Lexapro 
E)  Bextra 
A)  Celexa 
B)  Cephalexin 
C)  Zyprexa 
D)  Lexapro 
E)  Bextra

Question 19

Tardive dyskinesia is characterized by:

Accepted Answer

A)  increased compulsive motor activity. 
B)  resting tremor and rigidity. 
C)  akinesia. 
D)  involuntary, repetitive body movements involving the tongue, lips, face, and jaw. 
A)  increased compulsive motor activity. 
B)  resting tremor and rigidity. 
C)  akinesia. 
D)  involuntary, repetitive body movements involving the tongue, lips, face, and jaw.

Question 20

Which of the following psychiatric disorders involves a loss of the perception of reality?

Accepted Answer

A)  Bipolar affective disorder 
B)  Schizophrenia 
C)  Panic disorder 
D)  Obsessive-compulsive disorder 
A)  Bipolar affective disorder 
B)  Schizophrenia 
C)  Panic disorder 
D)  Obsessive-compulsive disorder

Exam 17: Drugs for the Treatment of Central Nervous System Disorders

The amount of any drug prescribed for a depressed patient should not exceed a _____-day supply.

First-generation antipsychotic therapy must often be combined with _____ drugs such as benztropine to control excessive extrapyramidal stimulation.

Which antidepressant drug carries a "black box" warning regarding its potential to cause life-threatening liver failure?

Which of the following are adverse reactions associated with selective serotonin reuptake inhibitors (SSRIs)?

Which of the following medications is used to treat bipolar depression?

Of the tricyclic antidepressants listed, which one is most sedating?

Dental local anesthetic with vasoconstricting agents must be limited to the cardiac dose for patients taking:

All antidepressants will carry a boxed warning about the potential for patient suicide.

Which of the following are true of second-generation antipsychotics in contrast to first-generation antipsychotics? (Select all that apply.)

Patients taking first-generation antipsychotics can experience severe intermittent temporomandibular joint (TMJ)pain. This pain is a consequence of:

All of the following symptoms are "negative" (passive)symptoms of psychoses except for which one?

Epinephrine should not be used to treat vasomotor collapse in patients taking first-generation antipsychotics because the first-generation antipsychotics are:

The chemoreceptor trigger zone (CTZ)is a site of action for prochlorperazine and promethazine.

Extrapyramidal reactions such as an acute spasm of the mandible caused by first-generation antipsychotics such as phenothiazines:

First-generation antipsychotics would have little effect on which of the following symptoms of psychosis?

Second-generation antipsychotics have fewer side effects than first-generation antipsychotics.

Which of the following second-generation antipsychotics is associated with agranulocytosis?

Which of the following agents is classified as an antipsychotic?

Tardive dyskinesia is characterized by:

Which of the following psychiatric disorders involves a loss of the perception of reality?

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