Question 1

Which of the following statements is true of COX II?

Accepted Answer

A)  It is a widely distributed constitutive enzyme. 
B)  It is responsible for the adverse reactions of the NSAIDs. 
C)  It is synthesized only when inflammation occurs. 
D)  It is not an enzyme. 
A)  It is a widely distributed constitutive enzyme. 
B)  It is responsible for the adverse reactions of the NSAIDs. 
C)  It is synthesized only when inflammation occurs. 
D)  It is not an enzyme. C

Question 2

Which of the following raises the pain threshold?

Accepted Answer

A)  Emotional instability 
B)  Sympathy 
C)  Sleep 
D)  Both a and c 
E)  Both b and c 
A)  Emotional instability 
B)  Sympathy 
C)  Sleep 
D)  Both a and c 
E)  Both b and c E

Question 3

A person should _____ aspirin if he or she suspects he or she may be having a heart attack provided there is not an aspirin allergy, hypersensitivity, or another contraindication.

Accepted Answer

A)  completely avoid 
B)  chew one low dose 
C)  take the maximum daily recommended dose of 4,000 mg of 
D)  take 325 to 650 mg every 4 hours of 
A)  completely avoid 
B)  chew one low dose 
C)  take the maximum daily recommended dose of 4,000 mg of 
D)  take 325 to 650 mg every 4 hours of B

Question 4

Which of the following agents would be least useful in alleviating fever?

Accepted Answer

A)  Piroxicam 
B)  Acetaminophen 
C)  Diflunisal 
D)  Probenecid 
E)  Aspirin 
A)  Piroxicam 
B)  Acetaminophen 
C)  Diflunisal 
D)  Probenecid 
E)  Aspirin

Question 5

Which of the following agents is known to have a drug interaction with lithium?

Accepted Answer

A)  Aspirin 
B)  Naproxen 
C)  Acetaminophen 
D)  Oxycodone 
A)  Aspirin 
B)  Naproxen 
C)  Acetaminophen 
D)  Oxycodone

Question 6

A drug interaction between aspirin and _____ can result in significant bleeding.

Accepted Answer

A)  probenecid 
B)  warfarin 
C)  methotrexate 
D)  sulfonylureas 
A)  probenecid 
B)  warfarin 
C)  methotrexate 
D)  sulfonylureas

Question 7

Dental pain is best managed with which of the following choices?

Accepted Answer

A)  Codeine 60 mg 
B)  Ibuprofen 400 mg 
C)  Acetaminophen 650 mg 
D)  Aspirin 650 mg 
E)  Placebo 
A)  Codeine 60 mg 
B)  Ibuprofen 400 mg 
C)  Acetaminophen 650 mg 
D)  Aspirin 650 mg 
E)  Placebo

Question 8

Which of the following drugs can be substituted for aspirin in patients displaying the aspirin hypersensitivity triad?

Accepted Answer

A)  Ibuprofen 
B)  Naproxen 
C)  Codeine 
D)  Piroxicam 
A)  Ibuprofen 
B)  Naproxen 
C)  Codeine 
D)  Piroxicam

Question 9

Which of the following agents is intended to treat an acute attack of gout?

Accepted Answer

A)  Probenecid 
B)  Codeine 
C)  Colchicine 
D)  Acetaminophen 
E)  Both a and c 
A)  Probenecid 
B)  Codeine 
C)  Colchicine 
D)  Acetaminophen 
E)  Both a and c

Question 10

Alcohol consumption stimulates the breakdown of acetaminophen, thereby decreasing the toxic potential of acetaminophen use.

Accepted Answer

A)  Both parts of the statement are true. 
B)  Both parts of the statement are false. 
C)  The first part of the statement is true; the second part is false. 
D)  The first part of the statement is false; the second part is true. 
A)  Both parts of the statement are true. 
B)  Both parts of the statement are false. 
C)  The first part of the statement is true; the second part is false. 
D)  The first part of the statement is false; the second part is true.

Question 11

Pain:

Accepted Answer

A)  brings people to the dental office. 
B)  keeps people from the dental office. 
C)  can be effectively treated with inactive pills (placebos). 
D)  does all of the above. 
A)  brings people to the dental office. 
B)  keeps people from the dental office. 
C)  can be effectively treated with inactive pills (placebos). 
D)  does all of the above.

Question 12

All of the following are characteristics of aspirin toxicity (salicylism)except:

Accepted Answer

A)  dimness of vision. 
B)  hyperthermia. 
C)  electrolyte imbalance. 
D)  hepatic necrosis. 
E)  tinnitus. 
A)  dimness of vision. 
B)  hyperthermia. 
C)  electrolyte imbalance. 
D)  hepatic necrosis. 
E)  tinnitus.

Question 13

Prostacyclin _____ aggregation of platelets and thromboxane A₂ ____ aggregation of platelets.

Accepted Answer

A)  stimulates; stimulates 
B)  stimulates; inhibits 
C)  inhibits; stimulates 
D)  inhibits; inhibits 
A)  stimulates; stimulates 
B)  stimulates; inhibits 
C)  inhibits; stimulates 
D)  inhibits; inhibits

Question 14

Low-dose aspirin therapy is recommended for which of the following? (Select all that apply.)

Accepted Answer

A)  People who have had heart bypass surgery 
B)  Men aged 45 to 79 with no history of heart disease 
C)  Women aged 55 to 79 with no history of heart disease 
D)  A person with gastroesophageal reflux disease (GER
D)  
A)  People who have had heart bypass surgery 
B)  Men aged 45 to 79 with no history of heart disease 
C)  Women aged 55 to 79 with no history of heart disease 
D)  A person with gastroesophageal reflux disease (GER
D)

Question 15

The pain threshold varies greatly in individuals because of different perceptions of pain.

Accepted Answer

A)  Both parts of the statements are true. 
B)  Both parts of the statements are false. 
C)  The first part of the statement is true; the second part is false. 
D)  The first part of the statement is false; the second part is true. 
A)  Both parts of the statements are true. 
B)  Both parts of the statements are false. 
C)  The first part of the statement is true; the second part is false. 
D)  The first part of the statement is false; the second part is true.

Question 16

Which of the following is true concerning NSAIDs?

Accepted Answer

A)  Many authors agree that the NSAIDs are the most useful drug group for the treatment of dental pain. 
B)  Unlike aspirin, NSAIDs do not inhibit the enzyme cyclooxygenase (COX). 
C)  Most NSAIDs reach a peak blood level in approximately 20 minutes. 
D)  NSAIDs do not have a significant antiinflammatory effect. 
A)  Many authors agree that the NSAIDs are the most useful drug group for the treatment of dental pain. 
B)  Unlike aspirin, NSAIDs do not inhibit the enzyme cyclooxygenase (COX). 
C)  Most NSAIDs reach a peak blood level in approximately 20 minutes. 
D)  NSAIDs do not have a significant antiinflammatory effect.

Question 17

Probenecid and allopurinol both inhibit the synthesis of uric acid.

Accepted Answer

A) True 
 B)False

Question 18

Two components of pain include perception and reaction.

Accepted Answer

A) True 
 B)False

Question 19

Who is most likely to experience the most cases of accidental overdose with acetaminophen?

Accepted Answer

A)  Infants 
B)  Children 
C)  Young adults 
D)  Older adults 
A)  Infants 
B)  Children 
C)  Young adults 
D)  Older adults

Question 20

Aspirin can be used most safely in patients who:

Accepted Answer

A)  have arthritis. 
B)  have gout. 
C)  have ulcers. 
D)  are pregnant. 
A)  have arthritis. 
B)  have gout. 
C)  have ulcers. 
D)  are pregnant.

Exam 5: Nonopioid (Nonnarcotic)Analgesics

Which of the following statements is true of COX II?

Which of the following raises the pain threshold?

A person should _____ aspirin if he or she suspects he or she may be having a heart attack provided there is not an aspirin allergy, hypersensitivity, or another contraindication.

Which of the following agents would be least useful in alleviating fever?

Which of the following agents is known to have a drug interaction with lithium?

A drug interaction between aspirin and _____ can result in significant bleeding.

Dental pain is best managed with which of the following choices?

Which of the following drugs can be substituted for aspirin in patients displaying the aspirin hypersensitivity triad?

Which of the following agents is intended to treat an acute attack of gout?

Alcohol consumption stimulates the breakdown of acetaminophen, thereby decreasing the toxic potential of acetaminophen use.

Pain:

All of the following are characteristics of aspirin toxicity (salicylism)except:

Prostacyclin _____ aggregation of platelets and thromboxane A₂ ____ aggregation of platelets.

Low-dose aspirin therapy is recommended for which of the following? (Select all that apply.)

The pain threshold varies greatly in individuals because of different perceptions of pain.

Which of the following is true concerning NSAIDs?

Probenecid and allopurinol both inhibit the synthesis of uric acid.

Two components of pain include perception and reaction.

Who is most likely to experience the most cases of accidental overdose with acetaminophen?

Aspirin can be used most safely in patients who:

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Adverse Reactions

Autonomic Drugs

Opioid (Narcotic)Analgesics and Antagonists

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Local Anesthetics

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Oral Conditions and Their Treatment

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Drugs for the Treatment of Cardiovascular Disease

Drugs for the Treatment of Gastrointestinal Disorders

Drugs for the Treatment of Seizure Disorders

Drugs for the Treatment of Central Nervous System Disorders

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Drugs for the Treatment of Respiratory Disorders

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Filters

Prostacyclin _ aggregation of platelets and thromboxane A₂ aggregation of platelets.