Question 1

Synonyms for nonopioid analgesics include:

Accepted Answer

A)  narcotic. 
B)  central. 
C)  antipyretic. 
D)  strong. 
A)  narcotic. 
B)  central. 
C)  antipyretic. 
D)  strong.

Question 2

Caffeine is often combined with aspirin because caffeine potentiates the analgesic effect of aspirin and other analgesics.

Accepted Answer

A)  Both parts of the statement are true. 
B)  Both parts of the statement are false. 
C)  The first part of the statement is true; the second part is false. 
D)  The first part of the statement is false; the second part is true. 
A)  Both parts of the statement are true. 
B)  Both parts of the statement are false. 
C)  The first part of the statement is true; the second part is false. 
D)  The first part of the statement is false; the second part is true.

Question 3

Which of the following choices is currently the most popular COX II-specific agent on the market?

Accepted Answer

A)  Celecoxib 
B)  Rofecoxib 
C)  Valdecoxib 
D)  Indomethacin 
A)  Celecoxib 
B)  Rofecoxib 
C)  Valdecoxib 
D)  Indomethacin

Question 4

Salicylates' mechanism of action involves inhibiting prostaglandin synthesis.

Accepted Answer

A) True 
 B)False

Question 5

Aspirin should not be given to children until they are 18 years of age.

Accepted Answer

A) True 
 B)False

Question 6

NSAIDs carry "black box warnings" for which of the following types of events? (Select all that apply.)

Accepted Answer

A)  Respiratory 
B)  Gastrointestinal 
C)  Cardiovascular 
D)  Endocrine 
A)  Respiratory 
B)  Gastrointestinal 
C)  Cardiovascular 
D)  Endocrine

Question 7

An acute overdose with acetaminophen may damage the:

Accepted Answer

A)  eyes. 
B)  liver. 
C)  spleen. 
D)  kidney. 
A)  eyes. 
B)  liver. 
C)  spleen. 
D)  kidney.

Question 8

Which of the following NSAIDs is designated U.S. Food and Drug Administration (FDA)pregnancy category B?

Accepted Answer

A)  Naproxen (Naprosyn) 
B)  Diflunisal (Dolobid) 
C)  Tolmetin (Tolectin) 
D)  Mefanamic acid (Ponstel) 
A)  Naproxen (Naprosyn) 
B)  Diflunisal (Dolobid) 
C)  Tolmetin (Tolectin) 
D)  Mefanamic acid (Ponstel)

Question 9

Oral administration with _____ is indicated only as continuation to intravenous (IV)or intramuscular (IM)therapy.

Accepted Answer

A)  fenoprofen 
B)  ketorolac 
C)  naproxen sodium 
D)  diflunisal 
A)  fenoprofen 
B)  ketorolac 
C)  naproxen sodium 
D)  diflunisal

Question 10

Which of the following is the most common side effect from aspirin?

Accepted Answer

A)  Gastrointestinal effects 
B)  Bleeding 
C)  Hepatic and renal effects 
D)  Hypersensitivity 
A)  Gastrointestinal effects 
B)  Bleeding 
C)  Hepatic and renal effects 
D)  Hypersensitivity

Question 11

The incidence of true aspirin allergy is:

Accepted Answer

A)  approximately 10%. 
B)  between 2% and 5%. 
C)  less than 1%. 
D)  unknown; it has not ever been recorded. 
A)  approximately 10%. 
B)  between 2% and 5%. 
C)  less than 1%. 
D)  unknown; it has not ever been recorded.

Question 12

Which of the following NSAIDs is considered the drug of choice for management of dental pain when a NSAID is indicated?

Accepted Answer

A)  Naproxen 
B)  Naproxen sodium 
C)  Ibuprofen 
D)  Diflunisal 
A)  Naproxen 
B)  Naproxen sodium 
C)  Ibuprofen 
D)  Diflunisal

Question 13

Pain relief by nonopioid analgesics is mediated via action:

Accepted Answer

A)  at the central nervous system (CNS). 
B)  at the peripheral nervous system. 
C)  both centrally and peripherally. 
D)  None of the above are correct. 
A)  at the central nervous system (CNS). 
B)  at the peripheral nervous system. 
C)  both centrally and peripherally. 
D)  None of the above are correct.

Question 14

The action of nonopioid analgesics is related to their ability to inhibit:

Accepted Answer

A)  the CNS. 
B)  prostaglandin synthesis. 
C)  release of epinephrine. 
D)  release of acetylcholine. 
A)  the CNS. 
B)  prostaglandin synthesis. 
C)  release of epinephrine. 
D)  release of acetylcholine.

Question 15

Acetaminophen does not possess any of these clinically significant _____ effects: (1)antipyretic, (2)antiinflammatory, (3)analgesic.

Accepted Answer

A)  1, 2, 3 
B)  1 and 2 
C)  1 and 3 
D)  1 
E)  2 
A)  1, 2, 3 
B)  1 and 2 
C)  1 and 3 
D)  1 
E)  2

Question 16

Which of the following statements is true regarding aspirin and the clotting mechanism?

Accepted Answer

A)  Aspirin reversibly interferes with the clotting mechanism by reducing platelet adhesiveness. 
B)  Replacement of all of the affected platelets is required to produce normal clotting. 
C)  With lower doses of aspirin, 1 1/2 days should elapse to obtain normal clotting. 
D)  Aspirin stimulates production of prothrombin. 
A)  Aspirin reversibly interferes with the clotting mechanism by reducing platelet adhesiveness. 
B)  Replacement of all of the affected platelets is required to produce normal clotting. 
C)  With lower doses of aspirin, 1 1/2 days should elapse to obtain normal clotting. 
D)  Aspirin stimulates production of prothrombin.

Question 17

Raising the pain threshold increases one's reaction to pain.

Accepted Answer

A) True 
 B)False

Question 18

What is the usual adult dosage of aspirin for the treatment of pain or fever?

Accepted Answer

A)  250 mg every 4 hours 
B)  3 to 6 g per day 
C)  650 mg every 4 hours 
D)  800 mg every 4 hours 
E)  160 mg per day 
A)  250 mg every 4 hours 
B)  3 to 6 g per day 
C)  650 mg every 4 hours 
D)  800 mg every 4 hours 
E)  160 mg per day

Question 19

Which of the following agents is a xanthine oxidase inhibitor?

Accepted Answer

A)  Colchicine 
B)  Ibuprofen 
C)  Allopurinol 
D)  Probenecid 
A)  Colchicine 
B)  Ibuprofen 
C)  Allopurinol 
D)  Probenecid

Question 20

Which of the following is true regarding these pharmacologic effects of therapeutic doses of acetaminophen?
(1)No effect on the cardiovascular system
(2)Does not produce gastric bleeding
(3)Does not affect platelet adhesiveness
(4)Does not affect uric acid excretion

Accepted Answer

A)  1, 2, 3, 4 
B)  1, 2, 3 
C)  2, 3, 4 
D)  1 only 
A)  1, 2, 3, 4 
B)  1, 2, 3 
C)  2, 3, 4 
D)  1 only

Exam 5: Nonopioid (Nonnarcotic)Analgesics

Synonyms for nonopioid analgesics include:

Caffeine is often combined with aspirin because caffeine potentiates the analgesic effect of aspirin and other analgesics.

Which of the following choices is currently the most popular COX II-specific agent on the market?

Salicylates' mechanism of action involves inhibiting prostaglandin synthesis.

Aspirin should not be given to children until they are 18 years of age.

NSAIDs carry "black box warnings" for which of the following types of events? (Select all that apply.)

An acute overdose with acetaminophen may damage the:

Which of the following NSAIDs is designated U.S. Food and Drug Administration (FDA)pregnancy category B?

Oral administration with _____ is indicated only as continuation to intravenous (IV)or intramuscular (IM)therapy.

Which of the following is the most common side effect from aspirin?

The incidence of true aspirin allergy is:

Which of the following NSAIDs is considered the drug of choice for management of dental pain when a NSAID is indicated?

Pain relief by nonopioid analgesics is mediated via action:

The action of nonopioid analgesics is related to their ability to inhibit:

Acetaminophen does not possess any of these clinically significant _____ effects: (1)antipyretic, (2)antiinflammatory, (3)analgesic.

Which of the following statements is true regarding aspirin and the clotting mechanism?

Raising the pain threshold increases one's reaction to pain.

What is the usual adult dosage of aspirin for the treatment of pain or fever?

Which of the following agents is a xanthine oxidase inhibitor?

Which of the following is true regarding these pharmacologic effects of therapeutic doses of acetaminophen? (1)No effect on the cardiovascular system (2)Does not produce gastric bleeding (3)Does not affect platelet adhesiveness (4)Does not affect uric acid excretion

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