Question 1

The use of barbiturates is absolutely contraindicated in patients with a positive family history of:

Accepted Answer

A)  high blood pressure. 
B)  diabetes. 
C)  porphyria. 
D)  adrenal insufficiency. 
A)  high blood pressure. 
B)  diabetes. 
C)  porphyria. 
D)  adrenal insufficiency. C

Question 2

Which of the following nonbenzodiazepine-benzodiazepine receptor agonists has the shortest half-life?

Accepted Answer

A)  Zolpidem (Ambien) 
B)  Zaleplon (Sonata) 
C)  Eszopiclone (Lunesta) 
A)  Zolpidem (Ambien) 
B)  Zaleplon (Sonata) 
C)  Eszopiclone (Lunesta) B

Question 3

Which of the following is the longest acting barbiturate?

Accepted Answer

A)  Methohexital (Brevital) 
B)  Pentobarbital (Nembutal) 
C)  Secobarbital (Seconal) 
D)  Phenobarbital (Luminal) 
A)  Methohexital (Brevital) 
B)  Pentobarbital (Nembutal) 
C)  Secobarbital (Seconal) 
D)  Phenobarbital (Luminal) D

Question 4

Which benzodiazepine is preferred for use in elderly patients?

Accepted Answer

A)  Benzodiazepines that require phase I metabolism and not phase II metabolism 
B)  Benzodiazepines that require phase II metabolism and not phase I metabolism 
C)  Benzodiazepines that require both phase I and phase II metabolism 
D)  Benzodiazepines that require neither phase I nor phase II metabolism 
A)  Benzodiazepines that require phase I metabolism and not phase II metabolism 
B)  Benzodiazepines that require phase II metabolism and not phase I metabolism 
C)  Benzodiazepines that require both phase I and phase II metabolism 
D)  Benzodiazepines that require neither phase I nor phase II metabolism

Question 5

Which of the following statements are true concerning the dental use of chloral hydrate? (Select all that apply.)

Accepted Answer

A)  Chloral hydrate is the most popular drug used in dentistry for the preoperative sedation of children. 
B)  Benzodiazepines are a safer choice for sedation of children. 
C)  Chloral hydrate is no longer available for use in the United States. 
D)  Chloral hydrate is a benzodiazepine. 
A)  Chloral hydrate is the most popular drug used in dentistry for the preoperative sedation of children. 
B)  Benzodiazepines are a safer choice for sedation of children. 
C)  Chloral hydrate is no longer available for use in the United States. 
D)  Chloral hydrate is a benzodiazepine.

Question 6

______ is the only intravenously (IV)administered benzodiazepine that is used for conscious sedation in oral health care.

Accepted Answer

A)  Chlordiazepoxide (Librium) 
B)  Lorazepam (Ativan) 
C)  Triazolam (Halcion) 
D)  Midazolam (Versed) 
A)  Chlordiazepoxide (Librium) 
B)  Lorazepam (Ativan) 
C)  Triazolam (Halcion) 
D)  Midazolam (Versed)

Question 7

Which of the following benzodiazepines is the drug of choice for treatment of repetitive, intractable seizures that require IV therapy?

Accepted Answer

A)  Chlordiazepoxide (Librium) 
B)  Diazepam (Valium) 
C)  Zolpidem (Ambien) 
D)  Eszopiclone (Lunesta) 
A)  Chlordiazepoxide (Librium) 
B)  Diazepam (Valium) 
C)  Zolpidem (Ambien) 
D)  Eszopiclone (Lunesta)

Question 8

Benzodiazepines are contraindicated in wide-angle glaucoma.

Accepted Answer

A) True 
 B)False

Question 9

Which of the following agents is a melatonin receptor agonist?

Accepted Answer

A)  Buspirone 
B)  Zaleplon 
C)  Chloral hydrate 
D)  Ramelteon 
E)  Tizanidine 
A)  Buspirone 
B)  Zaleplon 
C)  Chloral hydrate 
D)  Ramelteon 
E)  Tizanidine

Question 10

Sedatives potentiate analgesic agents.

Accepted Answer

A) True 
 B)False

Question 11

_____ may be used to reverse some of the effects of a benzodiazepine.

Accepted Answer

A)  Ramelteon (Rozerem) 
B)  Phenobarbital (Luminal) 
C)  Flumazenil (Romazicon) 
D)  Carisoprodol (Soma) 
A)  Ramelteon (Rozerem) 
B)  Phenobarbital (Luminal) 
C)  Flumazenil (Romazicon) 
D)  Carisoprodol (Soma)

Question 12

Which benzodiazepine would be most suitable for intramuscular (IM)administration?

Accepted Answer

A)  Midazolam 
B)  Diazepam 
C)  Alprazolam 
D)  Flurazepam 
A)  Midazolam 
B)  Diazepam 
C)  Alprazolam 
D)  Flurazepam

Question 13

When benzodiazepines are used in dentistry to produce conscious sedation, the appearance of __________ is used as an initial endpoint for the dose administered.

Accepted Answer

A)  flushed skin 
B)  miosis 
C)  ptosis 
D)  rapid eye movement 
A)  flushed skin 
B)  miosis 
C)  ptosis 
D)  rapid eye movement

Question 14

Which of the following muscle relaxants has peripheral rather than central action?

Accepted Answer

A)  Carisoprodol 
B)  Cyclobenzaprine 
C)  Tizanidine 
D)  Baclofen 
E)  Dantrolene 
A)  Carisoprodol 
B)  Cyclobenzaprine 
C)  Tizanidine 
D)  Baclofen 
E)  Dantrolene

Question 15

Which of the following parenteral benzodiazepines seems to have the greatest likelihood to produce amnesia?

Accepted Answer

A)  Diazepam (Valium) 
B)  Midazolam (Versed) 
C)  Triazolam (Halcion) 
D)  Eszopiclone (Lunesta) 
A)  Diazepam (Valium) 
B)  Midazolam (Versed) 
C)  Triazolam (Halcion) 
D)  Eszopiclone (Lunesta)

Question 16

Once a benzodiazepine is absorbed, the rate at which it reaches its site of action depends on which of the following? (Select all that apply.)

Accepted Answer

A)  Lipid solubility 
B)  Protein binding 
C)  Ionization 
D)  The Food and Drug Administration (FD
A) pregnancy category 
E)  First-order kinetics 
A)  Lipid solubility 
B)  Protein binding 
C)  Ionization 
D)  The Food and Drug Administration (FD
A) pregnancy category 
E)  First-order kinetics

Question 17

All of the following habits should be followed to minimize insomnia except for one. Which one is the exception?

Accepted Answer

A)  Light snack (warm milk)at bedtime 
B)  Awake at 6 AM even if sleep only began at 5 AM 
C)  Exercise within 3 hours of bedtime 
D)  Remaining in bed no longer than 20 minutes without sleeping 
E)  No smoking within 8 hours of bedtime 
A)  Light snack (warm milk)at bedtime 
B)  Awake at 6 AM even if sleep only began at 5 AM 
C)  Exercise within 3 hours of bedtime 
D)  Remaining in bed no longer than 20 minutes without sleeping 
E)  No smoking within 8 hours of bedtime

Question 18

Which agent has selective anxiolytic action without hypnotic, anticonvulsant, or muscle-relaxant properties?

Accepted Answer

A)  Zolpidem 
B)  Flumazenil 
C)  Meprobamate 
D)  Buspirone 
E)  Tizanidine 
A)  Zolpidem 
B)  Flumazenil 
C)  Meprobamate 
D)  Buspirone 
E)  Tizanidine

Question 19

Barbiturates have no significant analgesic effects.

Accepted Answer

A) True 
 B)False

Question 20

Which of the following statements are true concerning administration of benzodiazepines and pregnancy? (Select all that apply.)

Accepted Answer

A)  An increased risk of congenital malformation in infants of mothers taking benzodiazepines in the second trimester has been reported. 
B)  Most of the benzodiazepines are classified as U.S. Food and Drug Administration (FD
A) category D drugs; triazolam and temazepam are in FDA category X. 
C)  Near-term administration of benzodiazepines to the mother has resulted in floppy infant syndrome. 
D)  The administration of benzodiazepines is not a concern during pregnancy. 
A)  An increased risk of congenital malformation in infants of mothers taking benzodiazepines in the second trimester has been reported. 
B)  Most of the benzodiazepines are classified as U.S. Food and Drug Administration (FD
A) category D drugs; triazolam and temazepam are in FDA category X. 
C)  Near-term administration of benzodiazepines to the mother has resulted in floppy infant syndrome. 
D)  The administration of benzodiazepines is not a concern during pregnancy.

Exam 11: Antianxiety Agents

The use of barbiturates is absolutely contraindicated in patients with a positive family history of:

Which of the following nonbenzodiazepine-benzodiazepine receptor agonists has the shortest half-life?

Which of the following is the longest acting barbiturate?

Which benzodiazepine is preferred for use in elderly patients?

Which of the following statements are true concerning the dental use of chloral hydrate? (Select all that apply.)

______ is the only intravenously (IV)administered benzodiazepine that is used for conscious sedation in oral health care.

Which of the following benzodiazepines is the drug of choice for treatment of repetitive, intractable seizures that require IV therapy?

Benzodiazepines are contraindicated in wide-angle glaucoma.

Which of the following agents is a melatonin receptor agonist?

Sedatives potentiate analgesic agents.

_____ may be used to reverse some of the effects of a benzodiazepine.

Which benzodiazepine would be most suitable for intramuscular (IM)administration?

When benzodiazepines are used in dentistry to produce conscious sedation, the appearance of __________ is used as an initial endpoint for the dose administered.

Which of the following muscle relaxants has peripheral rather than central action?

Which of the following parenteral benzodiazepines seems to have the greatest likelihood to produce amnesia?

Once a benzodiazepine is absorbed, the rate at which it reaches its site of action depends on which of the following? (Select all that apply.)

All of the following habits should be followed to minimize insomnia except for one. Which one is the exception?

Which agent has selective anxiolytic action without hypnotic, anticonvulsant, or muscle-relaxant properties?

Barbiturates have no significant analgesic effects.

Which of the following statements are true concerning administration of benzodiazepines and pregnancy? (Select all that apply.)

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